BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 37684382)

  • 1. Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
    Yang ZX; Zhang Y; Wang Q; Zhang L; Liu YF; Zhang Y; Ren Y; Zhou C; Gao HW; Zhang NX; Feng LY
    Acta Pharmacol Sin; 2024 Jan; 45(1):36-51. PubMed ID: 37684382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein.
    Merghani MM; Ardah MT; Al Shamsi M; Kitada T; Haque ME
    Neurotoxicology; 2021 May; 84():41-52. PubMed ID: 33549656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reelin protects against pathological α-synuclein accumulation and dopaminergic neurodegeneration after environmental enrichment in Parkinson's disease.
    Cho E; Kim K; Kim H; Cho SR
    Neurobiol Dis; 2022 Dec; 175():105898. PubMed ID: 36270619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice.
    Kishimoto Y; Zhu W; Hosoda W; Sen JM; Mattson MP
    Neuromolecular Med; 2019 Sep; 21(3):239-249. PubMed ID: 31079293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
    Zhang Y; Wu Q; Zhang L; Wang Q; Yang Z; Liu J; Feng L
    Pharmacol Res; 2019 Dec; 150():104538. PubMed ID: 31707034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
    Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
    Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nigral overexpression of α-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome.
    O'Donovan SM; Crowley EK; Brown JR; O'Sullivan O; O'Leary OF; Timmons S; Nolan YM; Clarke DJ; Hyland NP; Joyce SA; Sullivan AM; O'Neill C
    Neurogastroenterol Motil; 2020 Jan; 32(1):e13726. PubMed ID: 31576631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cholecystokinin and glucagon-like peptide-1 analogues regulate intestinal tight junction, inflammation, dopaminergic neurons and α-synuclein accumulation in the colon of two Parkinson's disease mouse models.
    Su Y; Liu N; Zhang Z; Li H; Ma J; Yuan Y; Shi M; Liu J; Zhao Z; Zhang Z; Holscher C
    Eur J Pharmacol; 2022 Jul; 926():175029. PubMed ID: 35584709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson's disease mice.
    Karikari AA; McFleder RL; Ribechini E; Blum R; Bruttel V; Knorr S; Gehmeyr M; Volkmann J; Brotchie JM; Ahsan F; Haack B; Monoranu CM; Keber U; Yeghiazaryan R; Pagenstecher A; Heckel T; Bischler T; Wischhusen J; Koprich JB; Lutz MB; Ip CW
    Brain Behav Immun; 2022 Mar; 101():194-210. PubMed ID: 35032575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson's disease.
    Lu J; Wang C; Cheng X; Wang R; Yan X; He P; Chen H; Yu Z
    J Neuroinflammation; 2022 May; 19(1):113. PubMed ID: 35599331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.
    Castro-Sánchez S; García-Yagüe ÁJ; López-Royo T; Casarejos M; Lanciego JL; Lastres-Becker I
    Glia; 2018 Aug; 66(8):1752-1762. PubMed ID: 29624735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease.
    Geng L; Gao W; Saiyin H; Li Y; Zeng Y; Zhang Z; Li X; Liu Z; Gao Q; An P; Jiang N; Yu X; Chen X; Li S; Chen L; Lu B; Li A; Chen G; Shen Y; Zhang H; Tian M; Zhang Z; Li J
    Mol Neurodegener; 2023 Dec; 18(1):94. PubMed ID: 38041169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson's Disease.
    Ma SX; Seo BA; Kim D; Xiong Y; Kwon SH; Brahmachari S; Kim S; Kam TI; Nirujogi RS; Kwon SH; Dawson VL; Dawson TM; Pandey A; Na CH; Ko HS
    J Proteome Res; 2021 Jul; 20(7):3428-3443. PubMed ID: 34061533
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
    Brendza R; Gao X; Stark KL; Lin H; Lee SH; Hu C; Cai H; DiCara D; Hsiao YC; Ngu H; Foreman O; Baca M; Dohse M; Fortin JP; Corpuz R; Seshasayee D; Easton A; Ayalon G; Hötzel I; Chih B
    Neurobiol Dis; 2023 Feb; 177():105969. PubMed ID: 36535551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
    Richter F; Gao F; Medvedeva V; Lee P; Bove N; Fleming SM; Michaud M; Lemesre V; Patassini S; De La Rosa K; Mulligan CK; Sioshansi PC; Zhu C; Coppola G; Bordet T; Pruss RM; Chesselet MF
    Neurobiol Dis; 2014 Sep; 69():263-75. PubMed ID: 24844147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson's Disease Models.
    Verma DK; Seo BA; Ghosh A; Ma SX; Hernandez-Quijada K; Andersen JK; Ko HS; Kim YH
    Cells; 2021 Jul; 10(7):. PubMed ID: 34359864
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
    Mao X; Ou MT; Karuppagounder SS; Kam TI; Yin X; Xiong Y; Ge P; Umanah GE; Brahmachari S; Shin JH; Kang HC; Zhang J; Xu J; Chen R; Park H; Andrabi SA; Kang SU; Gonçalves RA; Liang Y; Zhang S; Qi C; Lam S; Keiler JA; Tyson J; Kim D; Panicker N; Yun SP; Workman CJ; Vignali DA; Dawson VL; Ko HS; Dawson TM
    Science; 2016 Sep; 353(6307):. PubMed ID: 27708076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
    Wegrzynowicz M; Bar-On D; Calo' L; Anichtchik O; Iovino M; Xia J; Ryazanov S; Leonov A; Giese A; Dalley JW; Griesinger C; Ashery U; Spillantini MG
    Acta Neuropathol; 2019 Oct; 138(4):575-595. PubMed ID: 31165254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
    Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
    Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparison between α-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model.
    Lu J; Sun F; Ma H; Qing H; Deng Y
    Biochem Biophys Res Commun; 2015 Sep; 464(4):988-993. PubMed ID: 26192120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.