206 related articles for article (PubMed ID: 37707950)
1. Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis.
Jalan-Sakrikar N; Anwar A; Yaqoob U; Gan C; Lagnado AB; Wixom AQ; Jurk D; Huebert RC
JCI Insight; 2023 Oct; 8(20):. PubMed ID: 37707950
[TBL] [Abstract][Full Text] [Related]
2. Cellular senescence in the cholangiopathies: a driver of immunopathology and a novel therapeutic target.
Trussoni CE; O'Hara SP; LaRusso NF
Semin Immunopathol; 2022 Jul; 44(4):527-544. PubMed ID: 35178659
[TBL] [Abstract][Full Text] [Related]
3. Downregulation of p16 Decreases Biliary Damage and Liver Fibrosis in the Mdr2
Kyritsi K; Francis H; Zhou T; Ceci L; Wu N; Yang Z; Meng F; Chen L; Baiocchi L; Kundu D; Kennedy L; Liangpunsakul S; Wu C; Glaser S; Alpini G
Gene Expr; 2020 Nov; 20(2):89-103. PubMed ID: 32393417
[TBL] [Abstract][Full Text] [Related]
4. Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2
Zhou T; Kyritsi K; Wu N; Francis H; Yang Z; Chen L; O'Brien A; Kennedy L; Ceci L; Meadows V; Kusumanchi P; Wu C; Baiocchi L; Skill NJ; Saxena R; Sybenga A; Xie L; Liangpunsakul S; Meng F; Alpini G; Glaser S
EBioMedicine; 2019 Oct; 48():130-142. PubMed ID: 31522982
[TBL] [Abstract][Full Text] [Related]
5. Genetic or pharmacological reduction of cholangiocyte senescence improves inflammation and fibrosis in the
Alsuraih M; O'Hara SP; Woodrum JE; Pirius NE; LaRusso NF
JHEP Rep; 2021 Jun; 3(3):100250. PubMed ID: 33870156
[TBL] [Abstract][Full Text] [Related]
6. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2
Meadows V; Kennedy L; Hargrove L; Demieville J; Meng F; Virani S; Reinhart E; Kyritsi K; Invernizzi P; Yang Z; Wu N; Liangpunsakul S; Alpini G; Francis H
Biochim Biophys Acta Mol Basis Dis; 2019 Dec; 1865(12):165557. PubMed ID: 31521820
[TBL] [Abstract][Full Text] [Related]
7. Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis.
Loarca L; De Assuncao TM; Jalan-Sakrikar N; Bronk S; Krishnan A; Huang B; Morton L; Trussoni C; Bonilla LM; Krueger E; O'Hara S; Splinter P; Shi G; Pisarello MJL; Gores GJ; Huebert RC; LaRusso NF
Lab Invest; 2017 Nov; 97(11):1385-1396. PubMed ID: 28892096
[TBL] [Abstract][Full Text] [Related]
8. Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma.
Chung BK; Karlsen TH; Folseraas T
Biochim Biophys Acta Mol Basis Dis; 2018 Apr; 1864(4 Pt B):1390-1400. PubMed ID: 28844951
[TBL] [Abstract][Full Text] [Related]
9. Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis, and Angiogenesis in a Model of Cholangitis.
Owen T; Carpino G; Chen L; Kundu D; Wills P; Ekser B; Onori P; Gaudio E; Alpini G; Francis H; Kennedy L
Cell Mol Gastroenterol Hepatol; 2023; 16(4):513-540. PubMed ID: 37336290
[TBL] [Abstract][Full Text] [Related]
10. ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.
O'Hara SP; Splinter PL; Trussoni CE; Pisarello MJ; Loarca L; Splinter NS; Schutte BF; LaRusso NF
J Biol Chem; 2017 Mar; 292(12):4833-4846. PubMed ID: 28184004
[TBL] [Abstract][Full Text] [Related]
11. Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
Reich M; Spomer L; Klindt C; Fuchs K; Stindt J; Deutschmann K; Höhne J; Liaskou E; Hov JR; Karlsen TH; Beuers U; Verheij J; Ferreira-Gonzalez S; Hirschfield G; Forbes SJ; Schramm C; Esposito I; Nierhoff D; Fickert P; Fuchs CD; Trauner M; García-Beccaria M; Gabernet G; Nahnsen S; Mallm JP; Vogel M; Schoonjans K; Lautwein T; Köhrer K; Häussinger D; Luedde T; Heikenwalder M; Keitel V
J Hepatol; 2021 Sep; 75(3):634-646. PubMed ID: 33872692
[TBL] [Abstract][Full Text] [Related]
12. Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.
Elßner C; Goeppert B; Longerich T; Scherr AL; Stindt J; Nanduri LK; Rupp C; Kather JN; Schmitt N; Kautz N; Breuhahn K; Ismail L; Heide D; Hetzer J; García-Beccaria M; Hövelmeyer N; Waisman A; Urbanik T; Mueller S; Gdynia G; Banales JM; Roessler S; Schirmacher P; Jäger D; Schölch S; Keitel V; Heikenwalder M; Schulze-Bergkamen H; Köhler BC
Gastroenterology; 2019 Mar; 156(4):1190-1205.e14. PubMed ID: 30445013
[TBL] [Abstract][Full Text] [Related]
13. Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis.
Tabibian JH; O'Hara SP; Splinter PL; Trussoni CE; LaRusso NF
Hepatology; 2014 Jun; 59(6):2263-75. PubMed ID: 24390753
[TBL] [Abstract][Full Text] [Related]
14. The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1.
Kang JH; Splinter PL; Trussoni CE; Pirius NE; Gores GJ; LaRusso NF; O'Hara SP
Gastroenterology; 2023 Jul; 165(1):228-243.e2. PubMed ID: 37059338
[TBL] [Abstract][Full Text] [Related]
15. Knockout of the Tachykinin Receptor 1 in the Mdr2
Ceci L; Francis H; Zhou T; Giang T; Yang Z; Meng F; Wu N; Kennedy L; Kyritsi K; Meadows V; Wu C; Liangpunsakul S; Franchitto A; Sybenga A; Ekser B; Mancinelli R; Onori P; Gaudio E; Glaser S; Alpini G
Am J Pathol; 2020 Nov; 190(11):2251-2266. PubMed ID: 32712019
[TBL] [Abstract][Full Text] [Related]
16. Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation.
Wu N; Meng F; Zhou T; Han Y; Kennedy L; Venter J; Francis H; DeMorrow S; Onori P; Invernizzi P; Bernuzzi F; Mancinelli R; Gaudio E; Franchitto A; Glaser S; Alpini G
FASEB J; 2017 Oct; 31(10):4305-4324. PubMed ID: 28634212
[TBL] [Abstract][Full Text] [Related]
17. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice.
Guicciardi ME; Krishnan A; Bronk SF; Hirsova P; Griffith TS; Gores GJ
Cell Death Dis; 2017 Jan; 8(1):e2535. PubMed ID: 28055006
[TBL] [Abstract][Full Text] [Related]
18. Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis.
Tabibian JH; Trussoni CE; O'Hara SP; Splinter PL; Heimbach JK; LaRusso NF
Lab Invest; 2014 Oct; 94(10):1126-33. PubMed ID: 25046437
[TBL] [Abstract][Full Text] [Related]
19. Cholangiocyte senescence in primary sclerosing cholangitis is associated with disease severity and prognosis.
Cazzagon N; Sarcognato S; Floreani A; Corrà G; De Martin S; Guzzardo V; Russo FP; Guido M
JHEP Rep; 2021 Jun; 3(3):100286. PubMed ID: 34041468
[TBL] [Abstract][Full Text] [Related]
20. Immune-mediated cholangiopathies in children: the need to better understand the pathophysiology for finding the future possible treatment targets.
Grama A; Mititelu A; Sîrbe C; Benţa G; Pop TL
Front Immunol; 2023; 14():1206025. PubMed ID: 37928553
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]