112 related articles for article (PubMed ID: 37710084)
1. Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia.
Yamazaki T; Mimura I; Kurata Y; Tanaka T; Nangaku M
Physiol Rep; 2023 Sep; 11(17):e15810. PubMed ID: 37710084
[TBL] [Abstract][Full Text] [Related]
2. Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.
Mimura I; Hirakawa Y; Kanki Y; Nakaki R; Suzuki Y; Tanaka T; Aburatani H; Nangaku M
Sci Rep; 2018 Feb; 8(1):3779. PubMed ID: 29491489
[TBL] [Abstract][Full Text] [Related]
3. Targeting enhancer of zeste homolog 2 protects against acute kidney injury.
Zhou X; Zang X; Guan Y; Tolbert T; Zhao TC; Bayliss G; Zhuang S
Cell Death Dis; 2018 Oct; 9(11):1067. PubMed ID: 30341286
[TBL] [Abstract][Full Text] [Related]
4. Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Li YM; Zhang J; Su LJ; Kellum JA; Peng ZY
Biochim Biophys Acta Mol Basis Dis; 2019 Mar; 1865(3):558-569. PubMed ID: 30562560
[TBL] [Abstract][Full Text] [Related]
5. TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
Jiang N; Huang R; Zhang J; Xu D; Li T; Sun Z; Su L; Peng Z
FASEB J; 2022 Apr; 36(4):e22228. PubMed ID: 35218571
[TBL] [Abstract][Full Text] [Related]
6. Long noncoding RNA MEG3 silencing protects against hypoxia-induced pheochromocytoma-12 cell injury through inhibition of TIMP2 promoter methylation.
Zheng XY; Lei BX; Lin YY; Sui MH; Zhang ML; Zhuang ZQ; Dong JT; Jin DM; Yan TB
J Cell Physiol; 2020 Feb; 235(2):1649-1662. PubMed ID: 31392726
[TBL] [Abstract][Full Text] [Related]
7. 3-deazaneplanocin A protects against cisplatin-induced renal tubular cell apoptosis and acute kidney injury by restoration of E-cadherin expression.
Ni J; Hou X; Wang X; Shi Y; Xu L; Zheng X; Liu N; Qiu A; Zhuang S
Cell Death Dis; 2019 May; 10(5):355. PubMed ID: 31043583
[TBL] [Abstract][Full Text] [Related]
8. EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion.
Yi X; Guo J; Guo J; Sun S; Yang P; Wang J; Li Y; Xie L; Cai J; Wang Z
Sci Rep; 2017 Jun; 7(1):3568. PubMed ID: 28620234
[TBL] [Abstract][Full Text] [Related]
9. EZH2 plays a crucial role in ischemia/reperfusion-induced acute kidney injury by regulating p38 signaling.
Liang H; Huang Q; Liao MJ; Xu F; Zhang T; He J; Zhang L; Liu HZ
Inflamm Res; 2019 Apr; 68(4):325-336. PubMed ID: 30820607
[TBL] [Abstract][Full Text] [Related]
10. Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia.
Sánchez-Navarro A; Pérez-Villalva R; Murillo-de-Ozores AR; Martínez-Rojas MÁ; Rodríguez-Aguilera JR; González N; Castañeda-Bueno M; Gamba G; Recillas-Targa F; Bobadilla NA
Sci Rep; 2021 Apr; 11(1):8769. PubMed ID: 33888767
[TBL] [Abstract][Full Text] [Related]
11. A chromatin modifier regulates Sertoli cell response to mono-(2-ethylhexyl) phthalate (MEHP) via tissue inhibitor of metalloproteinase 2 (TIMP2) signaling.
Zhang C; Lai JH; Hu B; Zhang S; Zhao J; Li W
Biochim Biophys Acta; 2014 Nov; 1839(11):1170-82. PubMed ID: 25153068
[TBL] [Abstract][Full Text] [Related]
12. 3-deazaneplanocin A, a histone methyltransferase inhibitor, improved the chemoresistance induced under hypoxia in melanoma cells.
Hosokawa M; Tetsumoto S; Yasui M; Kono Y; Ogawara KI
Biochem Biophys Res Commun; 2023 Oct; 677():26-30. PubMed ID: 37542772
[TBL] [Abstract][Full Text] [Related]
13. A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.
Zeybel M; Luli S; Sabater L; Hardy T; Oakley F; Leslie J; Page A; Moran Salvador E; Sharkey V; Tsukamoto H; Chu DCK; Singh US; Ponzoni M; Perri P; Di Paolo D; Mendivil EJ; Mann J; Mann DA
Mol Ther; 2017 Jan; 25(1):218-231. PubMed ID: 28129116
[TBL] [Abstract][Full Text] [Related]
14. Histone Methylation Inhibitor DZNep Ameliorated the Renal Ischemia-Reperfusion Injury
Li J; Qiu Y; Li L; Wang J; Cheuk YC; Sang R; Jia Y; Wang J; Zhang Y; Rong R
Front Med (Lausanne); 2020; 7():305. PubMed ID: 32754604
[TBL] [Abstract][Full Text] [Related]
15. Mechanisms Underlying Increased TIMP2 and IGFBP7 Urinary Excretion in Experimental AKI.
Johnson ACM; Zager RA
J Am Soc Nephrol; 2018 Aug; 29(8):2157-2167. PubMed ID: 29980651
[TBL] [Abstract][Full Text] [Related]
16. DZNep, inhibitor of S-adenosylhomocysteine hydrolase, down-regulates expression of SETDB1 H3K9me3 HMTase in human lung cancer cells.
Lee JK; Kim KC
Biochem Biophys Res Commun; 2013 Sep; 438(4):647-52. PubMed ID: 23933322
[TBL] [Abstract][Full Text] [Related]
17. 3-Deazaneplanocin A suppresses aggressive phenotype-related gene expression in an oral squamous cell carcinoma cell line.
Hatta M; Naganuma K; Kato K; Yamazaki J
Biochem Biophys Res Commun; 2015 Dec 4-11; 468(1-2):269-73. PubMed ID: 26505792
[TBL] [Abstract][Full Text] [Related]
18. Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells.
Nakagawa S; Sakamoto Y; Okabe H; Hayashi H; Hashimoto D; Yokoyama N; Tokunaga R; Sakamoto K; Kuroki H; Mima K; Beppu T; Baba H
Oncol Rep; 2014 Feb; 31(2):983-8. PubMed ID: 24337160
[TBL] [Abstract][Full Text] [Related]
19. Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Shi Y; Tao M; Wang Y; Zang X; Ma X; Qiu A; Zhuang S; Liu N
J Pathol; 2020 Jan; 250(1):79-94. PubMed ID: 31579944
[TBL] [Abstract][Full Text] [Related]
20. Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells.
Kikuchi J; Takashina T; Kinoshita I; Kikuchi E; Shimizu Y; Sakakibara-Konishi J; Oizumi S; Marquez VE; Nishimura M; Dosaka-Akita H
Lung Cancer; 2012 Nov; 78(2):138-43. PubMed ID: 22925699
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
