223 related articles for article (PubMed ID: 37712417)
1. Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation.
Stamateris RE; Landa-Galvan HV; Sharma RB; Darko C; Redmond D; Rane SG; Alonso LC
J Clin Invest; 2023 Sep; 133(18):. PubMed ID: 37712417
[TBL] [Abstract][Full Text] [Related]
2. Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
Marzo N; Mora C; Fabregat ME; Martín J; Usac EF; Franco C; Barbacid M; Gomis R
Diabetologia; 2004 Apr; 47(4):686-94. PubMed ID: 15298346
[TBL] [Abstract][Full Text] [Related]
3. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.
Kitamura T; Nakae J; Kitamura Y; Kido Y; Biggs WH; Wright CV; White MF; Arden KC; Accili D
J Clin Invest; 2002 Dec; 110(12):1839-47. PubMed ID: 12488434
[TBL] [Abstract][Full Text] [Related]
4. Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.
Tanabe K; Liu Z; Patel S; Doble BW; Li L; Cras-Méneur C; Martinez SC; Welling CM; White MF; Bernal-Mizrachi E; Woodgett JR; Permutt MA
PLoS Biol; 2008 Feb; 6(2):e37. PubMed ID: 18288891
[TBL] [Abstract][Full Text] [Related]
5. Involvement of the STAT5-cyclin D/CDK4-pRb pathway in β-cell proliferation stimulated by prolactin during pregnancy.
Zhao X; Xu Y; Wu Y; Zhang H; Shi H; Zhu H; Woo M; Wu X
Am J Physiol Endocrinol Metab; 2019 Jan; 316(1):E135-E144. PubMed ID: 30512986
[TBL] [Abstract][Full Text] [Related]
6. Cyclin-Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin.
Chirivella L; Kirstein M; Ferrón SR; Domingo-Muelas A; Durupt FC; Acosta-Umanzor C; Cano-Jaimez M; Pérez-Sánchez F; Barbacid M; Ortega S; Burks DJ; Fariñas I
Stem Cells; 2017 Dec; 35(12):2403-2416. PubMed ID: 28833887
[TBL] [Abstract][Full Text] [Related]
7. Pdx1 restores beta cell function in Irs2 knockout mice.
Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CV; Montminy MR; White MF
J Clin Invest; 2002 May; 109(9):1193-201. PubMed ID: 11994408
[TBL] [Abstract][Full Text] [Related]
8. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia.
Rane SG; Dubus P; Mettus RV; Galbreath EJ; Boden G; Reddy EP; Barbacid M
Nat Genet; 1999 May; 22(1):44-52. PubMed ID: 10319860
[TBL] [Abstract][Full Text] [Related]
9. XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.
Lee K; Chan JY; Liang C; Ip CK; Shi YC; Herzog H; Hughes WE; Bensellam M; Delghingaro-Augusto V; Koina ME; Nolan CJ; Laybutt DR
Diabetologia; 2022 Jun; 65(6):984-996. PubMed ID: 35316840
[TBL] [Abstract][Full Text] [Related]
10. An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
Casteels T; Zhang Y; Frogne T; Sturtzel C; Lardeau CH; Sen I; Liu X; Hong S; Pauler FM; Penz T; Brandstetter M; Barbieux C; Berishvili E; Heuser T; Bock C; Riedel CG; Meyer D; Distel M; Hecksher-Sørensen J; Li J; Kubicek S
Mol Metab; 2021 Dec; 54():101329. PubMed ID: 34454092
[TBL] [Abstract][Full Text] [Related]
11. The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.
Kim SY; Rane SG
Development; 2011 May; 138(10):1903-12. PubMed ID: 21490060
[TBL] [Abstract][Full Text] [Related]
12. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.
Nakae J; Biggs WH; Kitamura T; Cavenee WK; Wright CV; Arden KC; Accili D
Nat Genet; 2002 Oct; 32(2):245-53. PubMed ID: 12219087
[TBL] [Abstract][Full Text] [Related]
13. Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.
Kushner JA; Simpson L; Wartschow LM; Guo S; Rankin MM; Parsons R; White MF
J Biol Chem; 2005 Nov; 280(47):39388-93. PubMed ID: 16170201
[TBL] [Abstract][Full Text] [Related]
14. CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S; Lopez-Mejia IC; Denechaud PD; Escoté X; Castillo-Armengol J; Jimenez V; Chavey C; Giralt A; Lai Q; Zhang L; Martinez-Carreres L; Delacuisine B; Annicotte JS; Blanchet E; Huré S; Abella A; Tinahones FJ; Vendrell J; Dubus P; Bosch F; Kahn CR; Fajas L
J Clin Invest; 2016 Jan; 126(1):335-48. PubMed ID: 26657864
[TBL] [Abstract][Full Text] [Related]
15. Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.
Fiori JL; Shin YK; Kim W; Krzysik-Walker SM; González-Mariscal I; Carlson OD; Sanghvi M; Moaddel R; Farhang K; Gadkaree SK; Doyle ME; Pearson KJ; Mattison JA; de Cabo R; Egan JM
Diabetes; 2013 Oct; 62(10):3500-13. PubMed ID: 23884882
[TBL] [Abstract][Full Text] [Related]
16. Transgenic expression of a mutated cyclin-dependent kinase 4 (CDK4/R24C) in pancreatic beta-cells prevents progression of diabetes in db/db mice.
Miyawaki K; Inoue H; Keshavarz P; Mizuta K; Sato A; Sakamoto Y; Moritani M; Kunika K; Tanahashi T; Itakura M
Diabetes Res Clin Pract; 2008 Oct; 82(1):33-41. PubMed ID: 18678431
[TBL] [Abstract][Full Text] [Related]
17. FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice.
Kobayashi M; Kikuchi O; Sasaki T; Kim HJ; Yokota-Hashimoto H; Lee YS; Amano K; Kitazumi T; Susanti VY; Kitamura YI; Kitamura T
Am J Physiol Endocrinol Metab; 2012 Mar; 302(5):E603-13. PubMed ID: 22215655
[TBL] [Abstract][Full Text] [Related]
18. Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1.
Wang K; Cui X; Li F; Xia L; Wei T; Liu J; Fu W; Yang J; Hong T; Wei R
Am J Physiol Endocrinol Metab; 2023 Jan; 324(1):E97-E113. PubMed ID: 36383639
[TBL] [Abstract][Full Text] [Related]
19. The CDK4-pRB-E2F1 pathway controls insulin secretion.
Annicotte JS; Blanchet E; Chavey C; Iankova I; Costes S; Assou S; Teyssier J; Dalle S; Sardet C; Fajas L
Nat Cell Biol; 2009 Aug; 11(8):1017-23. PubMed ID: 19597485
[TBL] [Abstract][Full Text] [Related]
20. RNA-Seq Analysis of Islets to Characterise the Dedifferentiation in Type 2 Diabetes Model Mice db/db.
Neelankal John A; Ram R; Jiang FX
Endocr Pathol; 2018 Sep; 29(3):207-221. PubMed ID: 29542001
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
