209 related articles for article (PubMed ID: 37720104)
1. The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in
Johannessen JA; Formica M; Haukeland ALC; Bråthen NR; Al Outa A; Aarsund M; Therrien M; Enserink JM; Knævelsrud H
iScience; 2023 Oct; 26(10):107726. PubMed ID: 37720104
[No Abstract] [Full Text] [Related]
2. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.
Wu F; Nie S; Yao Y; Huo T; Li X; Wu X; Zhao J; Lin YL; Zhang Y; Mo Q; Song Y
Theranostics; 2021; 11(17):8172-8184. PubMed ID: 34373735
[TBL] [Abstract][Full Text] [Related]
3. Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
Thomas M; Gessner A; Vornlocher HP; Hadwiger P; Greil J; Heidenreich O
Blood; 2005 Nov; 106(10):3559-66. PubMed ID: 16046533
[TBL] [Abstract][Full Text] [Related]
4. Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.
Barve A; Vega A; Shah PP; Ghare S; Casson L; Wunderlich M; Siskind LJ; Beverly LJ
Cells; 2019 Oct; 8(11):. PubMed ID: 31717699
[TBL] [Abstract][Full Text] [Related]
5. MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia.
Kerry J; Godfrey L; Repapi E; Tapia M; Blackledge NP; Ma H; Ballabio E; O'Byrne S; Ponthan F; Heidenreich O; Roy A; Roberts I; Konopleva M; Klose RJ; Geng H; Milne TA
Cell Rep; 2017 Jan; 18(2):482-495. PubMed ID: 28076791
[TBL] [Abstract][Full Text] [Related]
6. H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Krivtsov AV; Feng Z; Lemieux ME; Faber J; Vempati S; Sinha AU; Xia X; Jesneck J; Bracken AP; Silverman LB; Kutok JL; Kung AL; Armstrong SA
Cancer Cell; 2008 Nov; 14(5):355-68. PubMed ID: 18977325
[TBL] [Abstract][Full Text] [Related]
7. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.
Bueno C; Montes R; Catalina P; Rodríguez R; Menendez P
Leukemia; 2011 Mar; 25(3):400-10. PubMed ID: 21135858
[TBL] [Abstract][Full Text] [Related]
8. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
[TBL] [Abstract][Full Text] [Related]
9. A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification.
Bueno C; Montes R; Melen GJ; Ramos-Mejia V; Real PJ; Ayllón V; Sanchez L; Ligero G; Gutierrez-Aranda I; Fernández AF; Fraga MF; Moreno-Gimeno I; Burks D; Plaza-Calonge Mdel C; Rodríguez-Manzaneque JC; Menendez P
Cell Res; 2012 Jun; 22(6):986-1002. PubMed ID: 22212479
[TBL] [Abstract][Full Text] [Related]
10. circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression.
Huang W; Fang K; Chen TQ; Zeng ZC; Sun YM; Han C; Sun LY; Chen ZH; Yang QQ; Pan Q; Luo XQ; Wang WT; Chen YQ
J Hematol Oncol; 2019 Oct; 12(1):103. PubMed ID: 31623653
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia.
Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
Onco Targets Ther; 2013; 6():1153-60. PubMed ID: 24009426
[TBL] [Abstract][Full Text] [Related]
12. Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.
van der Linden MH; Seslija L; Schneider P; Driessen EM; Castro PG; Stumpel DJ; van Roon E; de Boer J; Williams O; Pieters R; Stam RW
PLoS One; 2015; 10(3):e0120326. PubMed ID: 25793396
[TBL] [Abstract][Full Text] [Related]
13. Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.
Montes R; Ayllón V; Gutierrez-Aranda I; Prat I; Hernández-Lamas MC; Ponce L; Bresolin S; Te Kronnie G; Greaves M; Bueno C; Menendez P
Blood; 2011 May; 117(18):4746-58. PubMed ID: 21389315
[TBL] [Abstract][Full Text] [Related]
14. H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells.
Godfrey L; Crump NT; O'Byrne S; Lau IJ; Rice S; Harman JR; Jackson T; Elliott N; Buck G; Connor C; Thorne R; Knapp DJHF; Heidenreich O; Vyas P; Menendez P; Inglott S; Ancliff P; Geng H; Roberts I; Roy A; Milne TA
Leukemia; 2021 Jan; 35(1):90-106. PubMed ID: 32242051
[TBL] [Abstract][Full Text] [Related]
15. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
Gessner A; Thomas M; Castro PG; Büchler L; Scholz A; Brümmendorf TH; Soria NM; Vormoor J; Greil J; Heidenreich O
Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
[TBL] [Abstract][Full Text] [Related]
16. MicroRNA-142-3p inhibits cell proliferation in human acute lymphoblastic leukemia by targeting the MLL-AF4 oncogene.
Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
Mol Biol Rep; 2013 Dec; 40(12):6811-9. PubMed ID: 24057258
[TBL] [Abstract][Full Text] [Related]
17. The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis.
Yang L; Liu L; Gao H; Pinnamaneni JP; Sanagasetti D; Singh VP; Wang K; Mathison M; Zhang Q; Chen F; Mo Q; Rosengart T; Yang J
J Hematol Oncol; 2017 Oct; 10(1):159. PubMed ID: 28974232
[TBL] [Abstract][Full Text] [Related]
18. The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34
Prieto C; Marschalek R; Kühn A; Bursen A; Bueno C; Menéndez P
Oncotarget; 2017 Oct; 8(47):81936-81941. PubMed ID: 29137234
[TBL] [Abstract][Full Text] [Related]
19. Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology.
Muyrers-Chen I; Rozovskaia T; Lee N; Kersey JH; Nakamura T; Canaani E; Paro R
Oncogene; 2004 Nov; 23(53):8639-48. PubMed ID: 15378024
[TBL] [Abstract][Full Text] [Related]
20. Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.
Okuda H; Stanojevic B; Kanai A; Kawamura T; Takahashi S; Matsui H; Takaori-Kondo A; Yokoyama A
J Clin Invest; 2017 May; 127(5):1918-1931. PubMed ID: 28394257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]