186 related articles for article (PubMed ID: 37723181)
1. Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR; Johansen MD; Balka KR; Ambrose RL; Gearing LJ; Roest J; Vivian JP; Sapkota S; Jayasekara WSN; Wenholz DS; Aldilla VR; Zeng J; Miemczyk S; Nguyen DH; Hansbro NG; Venkatraman R; Kang JH; Pang ES; Thomas BJ; Alharbi AS; Rezwan R; O'Keeffe M; Donald WA; Ellyard JI; Wong W; Kumar N; Kile BT; Vinuesa CG; Kelly GE; Laczka OF; Hansbro PM; De Nardo D; Gantier MP
Nat Commun; 2023 Sep; 14(1):5666. PubMed ID: 37723181
[TBL] [Abstract][Full Text] [Related]
2. The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε.
He TS; Huang J; Chen T; Zhang Z; Cai K; Yu J; Xu LG
Microbiol Spectr; 2021 Dec; 9(3):e0145821. PubMed ID: 34908452
[TBL] [Abstract][Full Text] [Related]
3. TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Balka KR; Louis C; Saunders TL; Smith AM; Calleja DJ; D'Silva DB; Moghaddas F; Tailler M; Lawlor KE; Zhan Y; Burns CJ; Wicks IP; Miner JJ; Kile BT; Masters SL; De Nardo D
Cell Rep; 2020 Apr; 31(1):107492. PubMed ID: 32268090
[TBL] [Abstract][Full Text] [Related]
4. ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3.
Yu C; Wang B; Zhu Y; Zhang C; Ren L; Lei X; Xiang Z; Zhou Z; Huang H; Wang J; Zhao Z
Sci Signal; 2022 Jan; 15(715):eabh0068. PubMed ID: 34982578
[TBL] [Abstract][Full Text] [Related]
5. SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L; Zhao Y; Wang W; Wu P; Wang Z; Yu Y; Hou Z; Tan G; Liu Q
Front Immunol; 2021; 12():662989. PubMed ID: 34084167
[TBL] [Abstract][Full Text] [Related]
6. SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex.
Chen X; Yang X; Zheng Y; Yang Y; Xing Y; Chen Z
Protein Cell; 2014 May; 5(5):369-81. PubMed ID: 24622840
[TBL] [Abstract][Full Text] [Related]
7. DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Zhang K; Zhang Y; Xue J; Meng Q; Liu H; Bi C; Li C; Hu L; Yu H; Xiong T; Yang Y; Cui S; Bu Z; He X; Li J; Huang L; Weng C
Cell Rep; 2019 Jan; 26(5):1258-1272.e4. PubMed ID: 30699353
[TBL] [Abstract][Full Text] [Related]
8. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.
Clark K; Plater L; Peggie M; Cohen P
J Biol Chem; 2009 May; 284(21):14136-46. PubMed ID: 19307177
[TBL] [Abstract][Full Text] [Related]
9. Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.
tenOever BR; Sharma S; Zou W; Sun Q; Grandvaux N; Julkunen I; Hemmi H; Yamamoto M; Akira S; Yeh WC; Lin R; Hiscott J
J Virol; 2004 Oct; 78(19):10636-49. PubMed ID: 15367631
[TBL] [Abstract][Full Text] [Related]
10. Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.
Siu KL; Kok KH; Ng MJ; Poon VKM; Yuen KY; Zheng BJ; Jin DY
J Biol Chem; 2009 Jun; 284(24):16202-16209. PubMed ID: 19380580
[TBL] [Abstract][Full Text] [Related]
11. IKKε and TBK1 prevent RIPK1 dependent and independent inflammation.
Eren RO; Kaya GG; Schwarzer R; Pasparakis M
Nat Commun; 2024 Jan; 15(1):130. PubMed ID: 38167258
[TBL] [Abstract][Full Text] [Related]
12. Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study.
Lork M; Kreike M; Staal J; Beyaert R
Front Cell Dev Biol; 2018; 6():40. PubMed ID: 29755980
[TBL] [Abstract][Full Text] [Related]
13. Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis.
Hammaker D; Boyle DL; Firestein GS
Rheumatology (Oxford); 2012 Apr; 51(4):610-8. PubMed ID: 21613249
[TBL] [Abstract][Full Text] [Related]
14. SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.
Deng J; Zheng Y; Zheng SN; Nan ML; Han L; Zhang J; Jin Y; Pan JA; Gao C; Wang PH
J Med Virol; 2023 Mar; 95(3):e28561. PubMed ID: 36755358
[TBL] [Abstract][Full Text] [Related]
15. TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Fischer FA; Mies LFM; Nizami S; Pantazi E; Danielli S; Demarco B; Ohlmeyer M; Lee MSJ; Coban C; Kagan JC; Di Daniel E; Bezbradica JS
Proc Natl Acad Sci U S A; 2021 Sep; 118(38):. PubMed ID: 34518217
[TBL] [Abstract][Full Text] [Related]
16. Functionally distinct effects of the C-terminal regions of IKKε and TBK1 on type I IFN production.
Nakatsu Y; Matsuoka M; Chang TH; Otsuki N; Noda M; Kimura H; Sakai K; Kato H; Takeda M; Kubota T
PLoS One; 2014; 9(4):e94999. PubMed ID: 24722368
[TBL] [Abstract][Full Text] [Related]
17. Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets.
Yang Y; Ye F; Zhu N; Wang W; Deng Y; Zhao Z; Tan W
Sci Rep; 2015 Dec; 5():17554. PubMed ID: 26631542
[TBL] [Abstract][Full Text] [Related]
18. Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.
Huang L; Xiong T; Yu H; Zhang Q; Zhang K; Li C; Hu L; Zhang Y; Zhang L; Liu Q; Wang S; He X; Bu Z; Cai X; Cui S; Li J; Weng C
Biochem J; 2017 Jun; 474(12):2051-2065. PubMed ID: 28487378
[TBL] [Abstract][Full Text] [Related]
19. IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling.
Carr M; Mamand S; Chapman KL; Perrior T; Wagner SD
J Cell Mol Med; 2020 Oct; 24(19):11573-11582. PubMed ID: 32858764
[TBL] [Abstract][Full Text] [Related]
20. Crosstalk between TBK1/IKKε and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury.
Córdoba-David G; García-Giménez J; Cardoso Castelo-Branco R; Carrasco S; Cannata P; Ortiz A; Ramos AM
Front Pharmacol; 2022; 13():987979. PubMed ID: 36386242
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]