155 related articles for article (PubMed ID: 37728788)
1. Biophysical Characterization of p51 and p66 Monomers of HIV-1 Reverse Transcriptase with Their Inhibitors.
Seetaha S; Kamonsutthipaijit N; Yagi-Utsumi M; Seako Y; Yamaguchi T; Hannongbua S; Kato K; Choowongkomon K
Protein J; 2023 Dec; 42(6):741-752. PubMed ID: 37728788
[TBL] [Abstract][Full Text] [Related]
2. Homodimerization of the p51 subunit of HIV-1 reverse transcriptase.
Zheng X; Mueller GA; Cuneo MJ; Derose EF; London RE
Biochemistry; 2010 Apr; 49(13):2821-33. PubMed ID: 20180596
[TBL] [Abstract][Full Text] [Related]
3. Relative domain orientation of the L289K HIV-1 reverse transcriptase monomer.
Xi Z; Ilina TV; Guerrero M; Fan L; Sluis-Cremer N; Wang YX; Ishima R
Protein Sci; 2022 May; 31(5):e4307. PubMed ID: 35481647
[TBL] [Abstract][Full Text] [Related]
4. p66/p51 and p51/p51 recombinant forms of reverse transcriptase from human immunodeficiency virus type 1--interactions with primer tRNA(Lys3), initiation of cDNA synthesis, and effect of inhibitors.
Dufour E; El Dirani-Diab R; Boulmé F; Fournier M; Nevinsky G; Tarrago-Litvak L; Litvak S; Andreola ML
Eur J Biochem; 1998 Jan; 251(1-2):487-95. PubMed ID: 9492322
[TBL] [Abstract][Full Text] [Related]
5. Efavirenz binding site in HIV-1 reverse transcriptase monomers.
Braz VA; Barkley MD; Jockusch RA; Wintrode PL
Biochemistry; 2010 Dec; 49(49):10565-73. PubMed ID: 21090588
[TBL] [Abstract][Full Text] [Related]
6. Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.
Hsiou Y; Ding J; Das K; Clark AD; Hughes SH; Arnold E
Structure; 1996 Jul; 4(7):853-60. PubMed ID: 8805568
[TBL] [Abstract][Full Text] [Related]
7. The HIV-1 p66 homodimeric RT exhibits different conformations in the binding-competent and -incompetent NNRTI site.
Sharaf NG; Xi Z; Ishima R; Gronenborn AM
Proteins; 2017 Dec; 85(12):2191-2197. PubMed ID: 28905420
[TBL] [Abstract][Full Text] [Related]
8. Collective motions in HIV-1 reverse transcriptase: examination of flexibility and enzyme function.
Bahar I; Erman B; Jernigan RL; Atilgan AR; Covell DG
J Mol Biol; 1999 Jan; 285(3):1023-37. PubMed ID: 9887265
[TBL] [Abstract][Full Text] [Related]
9. Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.
Wang J; Smerdon SJ; Jäger J; Kohlstaedt LA; Rice PA; Friedman JM; Steitz TA
Proc Natl Acad Sci U S A; 1994 Jul; 91(15):7242-6. PubMed ID: 7518928
[TBL] [Abstract][Full Text] [Related]
10. Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
Das K; Ding J; Hsiou Y; Clark AD; Moereels H; Koymans L; Andries K; Pauwels R; Janssen PA; Boyer PL; Clark P; Smith RH; Kroeger Smith MB; Michejda CJ; Hughes SH; Arnold E
J Mol Biol; 1996 Dec; 264(5):1085-100. PubMed ID: 9000632
[TBL] [Abstract][Full Text] [Related]
11. Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.
Mulky A; Sarafianos SG; Arnold E; Wu X; Kappes JC
J Virol; 2004 Jul; 78(13):7089-96. PubMed ID: 15194785
[TBL] [Abstract][Full Text] [Related]
12. The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.
Schuckmann MM; Marchand B; Hachiya A; Kodama EN; Kirby KA; Singh K; Sarafianos SG
J Biol Chem; 2010 Dec; 285(49):38700-9. PubMed ID: 20876531
[TBL] [Abstract][Full Text] [Related]
13. Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)] (TSAO) derivatives is determined by the mutation Glu138-->Lys on the p51 subunit.
Jonckheere H; Taymans JM; Balzarini J; Velázquez S; Camarasa MJ; Desmyter J; De Clercq E; Anné J
J Biol Chem; 1994 Oct; 269(41):25255-8. PubMed ID: 7523383
[TBL] [Abstract][Full Text] [Related]
14. Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation.
Sluis-Cremer N; Arion D; Abram ME; Parniak MA
Int J Biochem Cell Biol; 2004 Sep; 36(9):1836-47. PubMed ID: 15183348
[TBL] [Abstract][Full Text] [Related]
15. The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors.
Balzarini J; Auwerx J; Rodríguez-Barrios F; Chedad A; Farkas V; Ceccherini-Silberstein F; García-Aparicio C; Velázquez S; De Clercq E; Perno CF; Camarasa MJ; Gago F
Mol Pharmacol; 2005 Jul; 68(1):49-60. PubMed ID: 15833734
[TBL] [Abstract][Full Text] [Related]
16. Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization.
Tachedjian G; Aronson HE; de los Santos M; Seehra J; McCoy JM; Goff SP
J Mol Biol; 2003 Feb; 326(2):381-96. PubMed ID: 12559908
[TBL] [Abstract][Full Text] [Related]
17. Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR.
Schmidt T; Schwieters CD; Clore GM
Proc Natl Acad Sci U S A; 2019 Sep; 116(36):17809-17816. PubMed ID: 31383767
[TBL] [Abstract][Full Text] [Related]
18. Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase.
Boyer PL; Ding J; Arnold E; Hughes SH
Antimicrob Agents Chemother; 1994 Sep; 38(9):1909-14. PubMed ID: 7529011
[TBL] [Abstract][Full Text] [Related]
19. The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.
Auwerx J; Van Nieuwenhove J; Rodríguez-Barrios F; de Castro S; Velázquez S; Ceccherini-Silberstein F; De Clercq E; Camarasa MJ; Perno CF; Gago F; Balzarini J
FEBS Lett; 2005 Apr; 579(11):2294-300. PubMed ID: 15848161
[TBL] [Abstract][Full Text] [Related]
20. Binding kinetics and affinities of heterodimeric versus homodimeric HIV-1 reverse transcriptase on DNA-DNA substrates at the single-molecule level.
Marko RA; Liu HW; Ablenas CJ; Ehteshami M; Götte M; Cosa G
J Phys Chem B; 2013 Apr; 117(16):4560-7. PubMed ID: 23305243
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
