BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 37741606)

  • 21. CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes.
    Olschok K; Han L; de Toledo MAS; Böhnke J; Graßhoff M; Costa IG; Theocharides A; Maurer A; Schüler HM; Buhl EM; Pannen K; Baumeister J; Kalmer M; Gupta S; Boor P; Gezer D; Brümmendorf TH; Zenke M; Chatain N; Koschmieder S
    Stem Cell Reports; 2021 Nov; 16(11):2768-2783. PubMed ID: 34678208
    [TBL] [Abstract][Full Text] [Related]  

  • 22. PAK1 overexpression promotes cell proliferation in cutaneous T cell lymphoma via suppression of PUMA and p21.
    Wang Y; Gu X; Li W; Zhang Q; Zhang C
    J Dermatol Sci; 2018 Apr; 90(1):60-67. PubMed ID: 29307600
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells.
    Ong CC; Jubb AM; Haverty PM; Zhou W; Tran V; Truong T; Turley H; O'Brien T; Vucic D; Harris AL; Belvin M; Friedman LS; Blackwood EM; Koeppen H; Hoeflich KP
    Proc Natl Acad Sci U S A; 2011 Apr; 108(17):7177-82. PubMed ID: 21482786
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of p21-activated kinase 1 in regulating the migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients.
    Fu D; Yang Y; Xiao Y; Lin H; Ye Y; Zhan Z; Liang L; Yang X; Sun L; Xu H
    Rheumatology (Oxford); 2012 Jul; 51(7):1170-80. PubMed ID: 22416254
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W; Lodish HF
    J Exp Med; 2004 Sep; 200(5):569-80. PubMed ID: 15337790
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis.
    Han Y; Yue L; Wei M; Ren X; Shao Z; Zhang L; Levine RL; Epling-Burnette PK
    PLoS One; 2017; 12(1):e0166014. PubMed ID: 28135282
    [TBL] [Abstract][Full Text] [Related]  

  • 27. EXEL-8232, a small-molecule JAK2 inhibitor, effectively treats thrombocytosis and extramedullary hematopoiesis in a murine model of myeloproliferative neoplasm induced by MPLW515L.
    Wernig G; Kharas MG; Mullally A; Leeman DS; Okabe R; George T; Clary DO; Gilliland DG
    Leukemia; 2012 Apr; 26(4):720-7. PubMed ID: 22005786
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Tyrosine 625 plays a key role and cooperates with tyrosine 630 in MPL W515L-induced signaling and myeloproliferative neoplasms.
    Yu C; Yang Q; Chen Y; Wang D; Levine R; Crispino J; Wen Q; Huang Z
    Cell Biosci; 2016; 6():34. PubMed ID: 27222706
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity.
    Song P; Song B; Liu J; Wang X; Nan X; Wang J
    Clin Transl Oncol; 2021 Apr; 23(4):892-901. PubMed ID: 32974862
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder.
    Harms FL; Kloth K; Bley A; Denecke J; Santer R; Lessel D; Hempel M; Kutsche K
    Am J Hum Genet; 2018 Oct; 103(4):579-591. PubMed ID: 30290153
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Myeloproliferative neoplasm stem cells.
    Mead AJ; Mullally A
    Blood; 2017 Mar; 129(12):1607-1616. PubMed ID: 28159736
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion.
    Han L; Schubert C; Köhler J; Schemionek M; Isfort S; Brümmendorf TH; Koschmieder S; Chatain N
    J Hematol Oncol; 2016 May; 9(1):45. PubMed ID: 27177927
    [TBL] [Abstract][Full Text] [Related]  

  • 33. LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain.
    Deguchi A; Miyoshi H; Kojima Y; Okawa K; Aoki M; Taketo MM
    J Biol Chem; 2010 Jun; 285(24):18283-90. PubMed ID: 20400510
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall remodeling.
    Kundumani-Sridharan V; Singh NK; Kumar S; Gadepalli R; Rao GN
    J Biol Chem; 2013 Jul; 288(30):22150-62. PubMed ID: 23737530
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Heat shock protein 90 inhibitors induce cell differentiation via the ubiquitin-dependent aurora kinase A degradation in a MPLW515L mouse model of primary myelofibrosis.
    Wang F; Zhang H; He B; Liu Z; Wu X; Liu Y; Xu X; Gou X; Wang H; Yang Q
    Hematol Oncol; 2023 Aug; 41(3):474-486. PubMed ID: 36422297
    [TBL] [Abstract][Full Text] [Related]  

  • 36. PAK1 Inhibition Suppresses the Proliferation, Migration and Invasion of Glioma Cells.
    Yi Q; Chen T; Zhou K; Ma Q; Sun Z; Shi H
    Curr Protein Pept Sci; 2023; 24(2):178-189. PubMed ID: 36573046
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dual targeting of JAK2 and ERK interferes with the myeloproliferative neoplasm clone and enhances therapeutic efficacy.
    Brkic S; Stivala S; Santopolo A; Szybinski J; Jungius S; Passweg JR; Tsakiris D; Dirnhofer S; Hutter G; Leonards K; Lischer HEL; Dettmer MS; Neel BG; Levine RL; Meyer SC
    Leukemia; 2021 Oct; 35(10):2875-2884. PubMed ID: 34480104
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis.
    Rojnuckarin P; Drachman JG; Kaushansky K
    Blood; 1999 Aug; 94(4):1273-82. PubMed ID: 10438715
    [TBL] [Abstract][Full Text] [Related]  

  • 39. FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine.
    Yeo D; He H; Patel O; Lowy AM; Baldwin GS; Nikfarjam M
    BMC Cancer; 2016 Jan; 16():24. PubMed ID: 26774265
    [TBL] [Abstract][Full Text] [Related]  

  • 40. p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer.
    Li Q; Mullins SR; Sloane BF; Mattingly RR
    Neoplasia; 2008 Apr; 10(4):314-29. PubMed ID: 18392133
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.