Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 37758718)

  • 1. Targeted inhibition of the methyltransferase SETD8 synergizes with the Wee1 inhibitor adavosertib in restraining glioblastoma growth.
    Della Monica R; Buonaiuto M; Cuomo M; Pagano C; Trio F; Costabile D; de Riso G; Cicala FS; Raia M; Franca RA; Del Basso De Caro M; Sorrentino D; Navarra G; Coppola L; Tripodi L; Pastore L; Hench J; Frank S; Schonauer C; Catapano G; Bifulco M; Chiariotti L; Visconti R
    Cell Death Dis; 2023 Sep; 14(9):638. PubMed ID: 37758718
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma.
    Mir SE; De Witt Hamer PC; Krawczyk PM; Balaj L; Claes A; Niers JM; Van Tilborg AA; Zwinderman AH; Geerts D; Kaspers GJ; Peter Vandertop W; Cloos J; Tannous BA; Wesseling P; Aten JA; Noske DP; Van Noorden CJ; Würdinger T
    Cancer Cell; 2010 Sep; 18(3):244-57. PubMed ID: 20832752
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer.
    Wada M; Kukita A; Sone K; Hamamoto R; Kaneko S; Komatsu M; Takahashi Y; Inoue F; Kojima M; Honjoh H; Taguchi A; Kashiyama T; Miyamoto Y; Tanikawa M; Tsuruga T; Mori-Uchino M; Wada-Hiraike O; Osuga Y; Fujii T
    Biomolecules; 2020 Dec; 10(12):. PubMed ID: 33339442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence.
    Shih CT; Chang YF; Chen YT; Ma CP; Chen HW; Yang CC; Lu JC; Tsai YS; Chen HC; Tan BC
    Aging Cell; 2017 Aug; 16(4):797-813. PubMed ID: 28514051
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma.
    Wu S; Wang S; Gao F; Li L; Zheng S; Yung WKA; Koul D
    Neuro Oncol; 2018 Jan; 20(1):78-91. PubMed ID: 29016926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Chk1 inhibitor SAR-020106 sensitizes human glioblastoma cells to irradiation, to temozolomide, and to decitabine treatment.
    Patties I; Kallendrusch S; Böhme L; Kendzia E; Oppermann H; Gaunitz F; Kortmann RD; Glasow A
    J Exp Clin Cancer Res; 2019 Oct; 38(1):420. PubMed ID: 31639020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting WEE1 by adavosertib inhibits the malignant phenotypes of hepatocellular carcinoma.
    Chen J; Jia X; Li Z; Song W; Jin C; Zhou M; Xie H; Zheng S; Song P
    Biochem Pharmacol; 2021 Jun; 188():114494. PubMed ID: 33684390
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death.
    Del Nagro CJ; Choi J; Xiao Y; Rangell L; Mohan S; Pandita A; Zha J; Jackson PK; O'Brien T
    Cell Cycle; 2014; 13(2):303-14. PubMed ID: 24247149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells.
    Cetin MH; Rieckmann T; Hoffer K; Riepen B; Christiansen S; Gatzemeier F; Feyerabend S; Schoof M; Schüller U; Petersen C; Mynarek M; Rothkamm K; Kriegs M; Struve N
    Radiat Oncol; 2023 Jan; 18(1):19. PubMed ID: 36709315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeted inhibition of the WEE1 kinase as a novel therapeutic strategy in neuroendocrine neoplasms.
    Weindl L; Atreya I; Dietrich P; Neubeck S; Neurath MF; Pavel M
    Endocr Relat Cancer; 2021 Jul; 28(9):605-620. PubMed ID: 34128828
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells.
    Ahmed SU; Carruthers R; Gilmour L; Yildirim S; Watts C; Chalmers AJ
    Cancer Res; 2015 Oct; 75(20):4416-28. PubMed ID: 26282173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.
    Bajbouj K; Mawrin C; Hartig R; Schulze-Luehrmann J; Wilisch-Neumann A; Roessner A; Schneider-Stock R
    J Neurooncol; 2012 May; 107(3):503-16. PubMed ID: 22270849
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.
    Veschi V; Liu Z; Voss TC; Ozbun L; Gryder B; Yan C; Hu Y; Ma A; Jin J; Mazur SJ; Lam N; Souza BK; Giannini G; Hager GL; Arrowsmith CH; Khan J; Appella E; Thiele CJ
    Cancer Cell; 2017 Jan; 31(1):50-63. PubMed ID: 28073004
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1-Oxoeudesm-11(13)-eno-12,8a-lactone induces G2/M arrest and apoptosis of human glioblastoma cells in vitro.
    Liu SS; Wang YF; Ma LS; Zheng BB; Li L; Xie WD; Li X
    Acta Pharmacol Sin; 2013 Feb; 34(2):271-81. PubMed ID: 23160341
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
    Herviou L; Ovejero S; Izard F; Karmous-Gadacha O; Gourzones C; Bellanger C; De Smedt E; Ma A; Vincent L; Cartron G; Jin J; De Bruyne E; Grimaud C; Julien E; Moreaux J
    Clin Epigenetics; 2021 Sep; 13(1):174. PubMed ID: 34530900
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells.
    Wang Y; Liu Q; Liu Z; Li B; Sun Z; Zhou H; Zhang X; Gong Y; Shao C
    Mutat Res; 2012 Jun; 734(1-2):20-9. PubMed ID: 22561209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Mar; 61(5):1957-63. PubMed ID: 11280752
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.