These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 37759202)

  • 1. Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.
    Das ND; Chang JC; Hon CC; Kelly ST; Ito S; Lizio M; Kaczkowski B; Watanabe H; Katsushima K; Natsume A; Koseki H; Kondo Y; Minoda A; Umehara T
    BMC Genomics; 2023 Sep; 24(1):574. PubMed ID: 37759202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
    Handoko L; Kaczkowski B; Hon CC; Lizio M; Wakamori M; Matsuda T; Ito T; Jeyamohan P; Sato Y; Sakamoto K; Yokoyama S; Kimura H; Minoda A; Umehara T
    Epigenetics; 2018; 13(4):410-431. PubMed ID: 30080437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma.
    Sengupta D; Kannan A; Kern M; Moreno MA; Vural E; Stack B; Suen JY; Tackett AJ; Gao L
    Epigenetics; 2015; 10(6):460-6. PubMed ID: 25941994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma.
    Kfoury N; Qi Z; Prager BC; Wilkinson MN; Broestl L; Berrett KC; Moudgil A; Sankararaman S; Chen X; Gertz J; Rich JN; Mitra RD; Rubin JB
    Proc Natl Acad Sci U S A; 2021 Apr; 118(16):. PubMed ID: 33850013
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells.
    Zhang W; Prakash C; Sum C; Gong Y; Li Y; Kwok JJ; Thiessen N; Pettersson S; Jones SJ; Knapp S; Yang H; Chin KC
    J Biol Chem; 2012 Dec; 287(51):43137-55. PubMed ID: 23086925
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells.
    Gonzales-Cope M; Sidoli S; Bhanu NV; Won KJ; Garcia BA
    BMC Genomics; 2016 Feb; 17():95. PubMed ID: 26847871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4.
    Gen Y; Muramatsu T; Inoue J; Inazawa J
    Cancer Res; 2021 Oct; 81(20):5190-5201. PubMed ID: 34353856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
    Morozov VM; Riva A; Sarwar S; Kim WJ; Li J; Zhou L; Licht JD; Daaka Y; Ishov AM
    Nucleic Acids Res; 2023 Oct; 51(19):10194-10217. PubMed ID: 37638746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BET bromodomain proteins are required for glioblastoma cell proliferation.
    Pastori C; Daniel M; Penas C; Volmar CH; Johnstone AL; Brothers SP; Graham RM; Allen B; Sarkaria JN; Komotar RJ; Wahlestedt C; Ayad NG
    Epigenetics; 2014 Apr; 9(4):611-20. PubMed ID: 24496381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
    Chen Y; Ying Y; Ma W; Ma H; Shi L; Gao X; Jia M; Li M; Song X; Kong W; Chen W; Zheng X; Muluh TA; Wang X; Wang M; Shu XS
    Cancer Res; 2024 Apr; 84(8):1237-1251. PubMed ID: 38241700
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.
    Wiese M; Hamdan FH; Kubiak K; Diederichs C; Gielen GH; Nussbaumer G; Carcaboso AM; Hulleman E; Johnsen SA; Kramm CM
    Cell Death Dis; 2020 Aug; 11(8):673. PubMed ID: 32826850
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.
    Dey A; Chitsaz F; Abbasi A; Misteli T; Ozato K
    Proc Natl Acad Sci U S A; 2003 Jul; 100(15):8758-63. PubMed ID: 12840145
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
    Devaiah BN; Case-Borden C; Gegonne A; Hsu CH; Chen Q; Meerzaman D; Dey A; Ozato K; Singer DS
    Nat Struct Mol Biol; 2016 Jun; 23(6):540-8. PubMed ID: 27159561
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.
    Olp MD; Zhu N; Smith BC
    Biochemistry; 2017 Oct; 56(41):5485-5495. PubMed ID: 28945351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression.
    Hu X; Lu X; Liu R; Ai N; Cao Z; Li Y; Liu J; Yu B; Liu K; Wang H; Zhou C; Wang Y; Han A; Ding F; Chen R
    J Biol Chem; 2014 Aug; 289(33):23154-23167. PubMed ID: 24939842
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.
    Khan YM; Kirkham P; Barnes PJ; Adcock IM
    PLoS One; 2014; 9(4):e95051. PubMed ID: 24759736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nanog requires BRD4 to maintain murine embryonic stem cell pluripotency and is suppressed by bromodomain inhibitor JQ1 together with Lefty1.
    Horne GA; Stewart HJ; Dickson J; Knapp S; Ramsahoye B; Chevassut T
    Stem Cells Dev; 2015 Apr; 24(7):879-91. PubMed ID: 25393219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails.
    Liu Y; Wang X; Zhang J; Huang H; Ding B; Wu J; Shi Y
    Biochemistry; 2008 Jun; 47(24):6403-17. PubMed ID: 18500820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver.
    Yamada A; Honma K; Mochizuki K; Goda T
    Metabolism; 2016 Oct; 65(10):1478-88. PubMed ID: 27621183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BRD4 in physiology and pathology: ''BET'' on its partners.
    Liang Y; Tian J; Wu T
    Bioessays; 2021 Dec; 43(12):e2100180. PubMed ID: 34697817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.