197 related articles for article (PubMed ID: 37759202)
1. Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.
Das ND; Chang JC; Hon CC; Kelly ST; Ito S; Lizio M; Kaczkowski B; Watanabe H; Katsushima K; Natsume A; Koseki H; Kondo Y; Minoda A; Umehara T
BMC Genomics; 2023 Sep; 24(1):574. PubMed ID: 37759202
[TBL] [Abstract][Full Text] [Related]
2. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
Handoko L; Kaczkowski B; Hon CC; Lizio M; Wakamori M; Matsuda T; Ito T; Jeyamohan P; Sato Y; Sakamoto K; Yokoyama S; Kimura H; Minoda A; Umehara T
Epigenetics; 2018; 13(4):410-431. PubMed ID: 30080437
[TBL] [Abstract][Full Text] [Related]
3. Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.
Jung M; Philpott M; Müller S; Schulze J; Badock V; Eberspächer U; Moosmayer D; Bader B; Schmees N; Fernández-Montalván A; Haendler B
J Biol Chem; 2014 Mar; 289(13):9304-19. PubMed ID: 24497639
[TBL] [Abstract][Full Text] [Related]
4. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma.
Sengupta D; Kannan A; Kern M; Moreno MA; Vural E; Stack B; Suen JY; Tackett AJ; Gao L
Epigenetics; 2015; 10(6):460-6. PubMed ID: 25941994
[TBL] [Abstract][Full Text] [Related]
5. Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma.
Kfoury N; Qi Z; Prager BC; Wilkinson MN; Broestl L; Berrett KC; Moudgil A; Sankararaman S; Chen X; Gertz J; Rich JN; Mitra RD; Rubin JB
Proc Natl Acad Sci U S A; 2021 Apr; 118(16):. PubMed ID: 33850013
[TBL] [Abstract][Full Text] [Related]
6. Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells.
Zhang W; Prakash C; Sum C; Gong Y; Li Y; Kwok JJ; Thiessen N; Pettersson S; Jones SJ; Knapp S; Yang H; Chin KC
J Biol Chem; 2012 Dec; 287(51):43137-55. PubMed ID: 23086925
[TBL] [Abstract][Full Text] [Related]
7. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells.
Gonzales-Cope M; Sidoli S; Bhanu NV; Won KJ; Garcia BA
BMC Genomics; 2016 Feb; 17():95. PubMed ID: 26847871
[TBL] [Abstract][Full Text] [Related]
8. miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4.
Gen Y; Muramatsu T; Inoue J; Inazawa J
Cancer Res; 2021 Oct; 81(20):5190-5201. PubMed ID: 34353856
[TBL] [Abstract][Full Text] [Related]
9. HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
Morozov VM; Riva A; Sarwar S; Kim WJ; Li J; Zhou L; Licht JD; Daaka Y; Ishov AM
Nucleic Acids Res; 2023 Oct; 51(19):10194-10217. PubMed ID: 37638746
[TBL] [Abstract][Full Text] [Related]
10. BET bromodomain proteins are required for glioblastoma cell proliferation.
Pastori C; Daniel M; Penas C; Volmar CH; Johnstone AL; Brothers SP; Graham RM; Allen B; Sarkaria JN; Komotar RJ; Wahlestedt C; Ayad NG
Epigenetics; 2014 Apr; 9(4):611-20. PubMed ID: 24496381
[TBL] [Abstract][Full Text] [Related]
11. Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
Chen Y; Ying Y; Ma W; Ma H; Shi L; Gao X; Jia M; Li M; Song X; Kong W; Chen W; Zheng X; Muluh TA; Wang X; Wang M; Shu XS
Cancer Res; 2024 Apr; 84(8):1237-1251. PubMed ID: 38241700
[TBL] [Abstract][Full Text] [Related]
12. Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.
Wiese M; Hamdan FH; Kubiak K; Diederichs C; Gielen GH; Nussbaumer G; Carcaboso AM; Hulleman E; Johnsen SA; Kramm CM
Cell Death Dis; 2020 Aug; 11(8):673. PubMed ID: 32826850
[TBL] [Abstract][Full Text] [Related]
13. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.
Dey A; Chitsaz F; Abbasi A; Misteli T; Ozato K
Proc Natl Acad Sci U S A; 2003 Jul; 100(15):8758-63. PubMed ID: 12840145
[TBL] [Abstract][Full Text] [Related]
14. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
Devaiah BN; Case-Borden C; Gegonne A; Hsu CH; Chen Q; Meerzaman D; Dey A; Ozato K; Singer DS
Nat Struct Mol Biol; 2016 Jun; 23(6):540-8. PubMed ID: 27159561
[TBL] [Abstract][Full Text] [Related]
15. Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.
Olp MD; Zhu N; Smith BC
Biochemistry; 2017 Oct; 56(41):5485-5495. PubMed ID: 28945351
[TBL] [Abstract][Full Text] [Related]
16. Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression.
Hu X; Lu X; Liu R; Ai N; Cao Z; Li Y; Liu J; Yu B; Liu K; Wang H; Zhou C; Wang Y; Han A; Ding F; Chen R
J Biol Chem; 2014 Aug; 289(33):23154-23167. PubMed ID: 24939842
[TBL] [Abstract][Full Text] [Related]
17. Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.
Khan YM; Kirkham P; Barnes PJ; Adcock IM
PLoS One; 2014; 9(4):e95051. PubMed ID: 24759736
[TBL] [Abstract][Full Text] [Related]
18. Nanog requires BRD4 to maintain murine embryonic stem cell pluripotency and is suppressed by bromodomain inhibitor JQ1 together with Lefty1.
Horne GA; Stewart HJ; Dickson J; Knapp S; Ramsahoye B; Chevassut T
Stem Cells Dev; 2015 Apr; 24(7):879-91. PubMed ID: 25393219
[TBL] [Abstract][Full Text] [Related]
19. Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails.
Liu Y; Wang X; Zhang J; Huang H; Ding B; Wu J; Shi Y
Biochemistry; 2008 Jun; 47(24):6403-17. PubMed ID: 18500820
[TBL] [Abstract][Full Text] [Related]
20. BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver.
Yamada A; Honma K; Mochizuki K; Goda T
Metabolism; 2016 Oct; 65(10):1478-88. PubMed ID: 27621183
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]