201 related articles for article (PubMed ID: 37759469)
1. Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy.
Castillo Bautista CM; Eismann K; Gentzel M; Pelucchi S; Mertens J; Walters HE; Yun MH; Sterneckert J
Cells; 2023 Sep; 12(18):. PubMed ID: 37759469
[TBL] [Abstract][Full Text] [Related]
2. FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Marrone L; Drexler HCA; Wang J; Tripathi P; Distler T; Heisterkamp P; Anderson EN; Kour S; Moraiti A; Maharana S; Bhatnagar R; Belgard TG; Tripathy V; Kalmbach N; Hosseinzadeh Z; Crippa V; Abo-Rady M; Wegner F; Poletti A; Troost D; Aronica E; Busskamp V; Weis J; Pandey UB; Hyman AA; Alberti S; Goswami A; Sterneckert J
Acta Neuropathol; 2019 Jul; 138(1):67-84. PubMed ID: 30937520
[TBL] [Abstract][Full Text] [Related]
3. Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L; Poser I; Casci I; Japtok J; Reinhardt P; Janosch A; Andree C; Lee HO; Moebius C; Koerner E; Reinhardt L; Cicardi ME; Hackmann K; Klink B; Poletti A; Alberti S; Bickle M; Hermann A; Pandey UB; Hyman AA; Sterneckert JL
Stem Cell Reports; 2018 Feb; 10(2):375-389. PubMed ID: 29358088
[TBL] [Abstract][Full Text] [Related]
4. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T; Suzuki N; Ishikawa M; Fujimori K; Sone T; Kawada J; Funayama R; Fujishima F; Mitsuzawa S; Ikeda K; Ono H; Shijo T; Osana S; Shirota M; Nakagawa T; Kitajima Y; Nishiyama A; Izumi R; Morimoto S; Okada Y; Kamei T; Nishida M; Nogami M; Kaneda S; Ikeuchi Y; Mitsuhashi H; Nakayama K; Fujii T; Warita H; Okano H; Aoki M
EBioMedicine; 2019 Jul; 45():362-378. PubMed ID: 31262712
[TBL] [Abstract][Full Text] [Related]
5. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
6. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
7. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
Lenzi J; De Santis R; de Turris V; Morlando M; Laneve P; Calvo A; Caliendo V; Chiò A; Rosa A; Bozzoni I
Dis Model Mech; 2015 Jul; 8(7):755-66. PubMed ID: 26035390
[TBL] [Abstract][Full Text] [Related]
8. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
[TBL] [Abstract][Full Text] [Related]
9. M
Di Timoteo G; Giuliani A; Setti A; Biagi MC; Lisi M; Santini T; Grandioso A; Mariani D; Castagnetti F; Perego E; Zappone S; Lattante S; Sabatelli M; Rotili D; Vicidomini G; Bozzoni I
Nat Commun; 2024 Jun; 15(1):5033. PubMed ID: 38866783
[TBL] [Abstract][Full Text] [Related]
10. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
Harley J; Patani R
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
[TBL] [Abstract][Full Text] [Related]
11. Disrupted autophagy and neuronal dysfunction in C. elegans knockin models of FUS amyotrophic lateral sclerosis.
Baskoylu SN; Chapkis N; Unsal B; Lins J; Schuch K; Simon J; Hart AC
Cell Rep; 2022 Jan; 38(4):110195. PubMed ID: 35081350
[TBL] [Abstract][Full Text] [Related]
12. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
Ichiyanagi N; Fujimori K; Yano M; Ishihara-Fujisaki C; Sone T; Akiyama T; Okada Y; Akamatsu W; Matsumoto T; Ishikawa M; Nishimoto Y; Ishihara Y; Sakuma T; Yamamoto T; Tsuiji H; Suzuki N; Warita H; Aoki M; Okano H
Stem Cell Reports; 2016 Apr; 6(4):496-510. PubMed ID: 26997647
[TBL] [Abstract][Full Text] [Related]
13. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
[TBL] [Abstract][Full Text] [Related]
14. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
Groen EJ; Fumoto K; Blokhuis AM; Engelen-Lee J; Zhou Y; van den Heuvel DM; Koppers M; van Diggelen F; van Heest J; Demmers JA; Kirby J; Shaw PJ; Aronica E; Spliet WG; Veldink JH; van den Berg LH; Pasterkamp RJ
Hum Mol Genet; 2013 Sep; 22(18):3690-704. PubMed ID: 23681068
[TBL] [Abstract][Full Text] [Related]
15. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W; Naujock M; Fumagalli L; Vandoorne T; Baatsen P; Boon R; Ordovás L; Patel A; Welters M; Vanwelden T; Geens N; Tricot T; Benoy V; Steyaert J; Lefebvre-Omar C; Boesmans W; Jarpe M; Sterneckert J; Wegner F; Petri S; Bohl D; Vanden Berghe P; Robberecht W; Van Damme P; Verfaillie C; Van Den Bosch L
Nat Commun; 2017 Oct; 8(1):861. PubMed ID: 29021520
[TBL] [Abstract][Full Text] [Related]
16. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
[TBL] [Abstract][Full Text] [Related]
17. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
[TBL] [Abstract][Full Text] [Related]
18. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
[TBL] [Abstract][Full Text] [Related]
19. FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS.
Harley J; Hagemann C; Serio A; Patani R
Brain; 2020 Dec; 143(12):e103. PubMed ID: 33253377
[No Abstract] [Full Text] [Related]
20. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]