169 related articles for article (PubMed ID: 37761914)
1. Non-Viral Episomal Vector Mediates Efficient Gene Transfer of the β-Globin Gene into K562 and Human Haematopoietic Progenitor Cells.
Lazaris VM; Simantirakis E; Stavrou EF; Verras M; Sgourou A; Keramida MK; Vassilopoulos G; Athanassiadou A
Genes (Basel); 2023 Sep; 14(9):. PubMed ID: 37761914
[TBL] [Abstract][Full Text] [Related]
2. Episomal vectors based on S/MAR and the β-globin Replicator, encoding a synthetic transcriptional activator, mediate efficient γ-globin activation in haematopoietic cells.
Stavrou EF; Simantirakis E; Verras M; Barbas C; Vassilopoulos G; Peterson KR; Athanassiadou A
Sci Rep; 2019 Dec; 9(1):19765. PubMed ID: 31874995
[TBL] [Abstract][Full Text] [Related]
3. The β-globin Replicator greatly enhances the potential of S/MAR based episomal vectors for gene transfer into human haematopoietic progenitor cells.
Stavrou EF; Lazaris VM; Giannakopoulos A; Papapetrou E; Spyridonidis A; Zoumbos NC; Gkountis A; Athanassiadou A
Sci Rep; 2017 Jan; 7():40673. PubMed ID: 28106085
[TBL] [Abstract][Full Text] [Related]
4. Comparative analysis of FV vectors with human α- or β-globin gene regulatory elements for the correction of β-thalassemia.
Morianos I; Siapati EK; Pongas G; Vassilopoulos G
Gene Ther; 2012 Mar; 19(3):303-11. PubMed ID: 21734726
[TBL] [Abstract][Full Text] [Related]
5. Physiological levels of HBB transgene expression from S/MAR element-based replicating episomal vectors.
Sgourou A; Routledge S; Spathas D; Athanassiadou A; Antoniou MN
J Biotechnol; 2009 Aug; 143(2):85-94. PubMed ID: 19559736
[TBL] [Abstract][Full Text] [Related]
6. Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia.
Nualkaew T; Sii-Felice K; Giorgi M; McColl B; Gouzil J; Glaser A; Voon HPJ; Tee HY; Grigoriadis G; Svasti S; Fucharoen S; Hongeng S; Leboulch P; Payen E; Vadolas J
Mol Ther; 2021 Sep; 29(9):2841-2853. PubMed ID: 33940155
[TBL] [Abstract][Full Text] [Related]
7. Gene Therapy for beta-thalassemia.
Malik P; Arumugam PI
Hematology Am Soc Hematol Educ Program; 2005; ():45-50. PubMed ID: 16304358
[TBL] [Abstract][Full Text] [Related]
8. Safe mobilization of CD34+ cells in adults with β-thalassemia and validation of effective globin gene transfer for clinical investigation.
Boulad F; Wang X; Qu J; Taylor C; Ferro L; Karponi G; Bartido S; Giardina P; Heller G; Prockop SE; Maggio A; Sadelain M; Rivière I
Blood; 2014 Mar; 123(10):1483-6. PubMed ID: 24429337
[TBL] [Abstract][Full Text] [Related]
9. The functional role of S/MARs in episomal vectors as defined by the stress-induced destabilization profile of the vector sequences.
Giannakopoulos A; Stavrou EF; Zarkadis I; Zoumbos N; Thrasher AJ; Athanassiadou A
J Mol Biol; 2009 Apr; 387(5):1239-49. PubMed ID: 19248788
[TBL] [Abstract][Full Text] [Related]
10. Successful correction of the human Cooley's anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator.
Malik P; Arumugam PI; Yee JK; Puthenveetil G
Ann N Y Acad Sci; 2005; 1054():238-49. PubMed ID: 16339671
[TBL] [Abstract][Full Text] [Related]
11. The new self-inactivating lentiviral vector for thalassemia gene therapy combining two HPFH activating elements corrects human thalassemic hematopoietic stem cells.
Papanikolaou E; Georgomanoli M; Stamateris E; Panetsos F; Karagiorga M; Tsaftaridis P; Graphakos S; Anagnou NP
Hum Gene Ther; 2012 Jan; 23(1):15-31. PubMed ID: 21875313
[TBL] [Abstract][Full Text] [Related]
12. The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number.
Persons DA; Hargrove PW; Allay ER; Hanawa H; Nienhuis AW
Blood; 2003 Mar; 101(6):2175-83. PubMed ID: 12411297
[TBL] [Abstract][Full Text] [Related]
13. Globin vector regulatory elements are active in early hematopoietic progenitor cells.
Cabriolu A; Odak A; Zamparo L; Yuan H; Leslie CS; Sadelain M
Mol Ther; 2022 Jun; 30(6):2199-2209. PubMed ID: 35247584
[TBL] [Abstract][Full Text] [Related]
14. Recombinant AAV2-mediated β-globin expression in human fetal hematopoietic cells from the aborted fetuses with β-thalassemia major.
Tian J; Wang F; Xue JF; Zhao F; Song LJ; Tan MQ
Int J Hematol; 2011 Jun; 93(6):691-699. PubMed ID: 21617888
[TBL] [Abstract][Full Text] [Related]
15. Engineered U7 snRNA mediates sustained splicing correction in erythroid cells from β-thalassemia/HbE patients.
Preedagasamzin S; Nualkaew T; Pongrujikorn T; Jinawath N; Kole R; Fucharoen S; Jearawiriyapaisarn N; Svasti S
Biochem Biophys Res Commun; 2018 Apr; 499(1):86-92. PubMed ID: 29550480
[TBL] [Abstract][Full Text] [Related]
16. Genetic therapy for beta-thalassemia: from the bench to the bedside.
Arumugam P; Malik P
Hematology Am Soc Hematol Educ Program; 2010; 2010():445-50. PubMed ID: 21239833
[TBL] [Abstract][Full Text] [Related]
17. Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia.
Hanawa H; Hargrove PW; Kepes S; Srivastava DK; Nienhuis AW; Persons DA
Blood; 2004 Oct; 104(8):2281-90. PubMed ID: 15198957
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.
Breda L; Casu C; Gardenghi S; Bianchi N; Cartegni L; Narla M; Yazdanbakhsh K; Musso M; Manwani D; Little J; Gardner LB; Kleinert DA; Prus E; Fibach E; Grady RW; Giardina PJ; Gambari R; Rivella S
PLoS One; 2012; 7(3):e32345. PubMed ID: 22479321
[TBL] [Abstract][Full Text] [Related]
19. [Optimization of β-globin Stable Expression Using the Third Generation Lentiviral Vector for β-thalassemia Therapy].
Yu Z; Tong S; Bai Y; Zhong XS
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2022 Jun; 30(3):844-850. PubMed ID: 35680815
[TBL] [Abstract][Full Text] [Related]
20. Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.
Zhao H; Pestina TI; Nasimuzzaman M; Mehta P; Hargrove PW; Persons DA
Blood; 2009 Jun; 113(23):5747-56. PubMed ID: 19365082
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]