BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 37762644)

  • 21. Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas.
    Drexler HG; Gignac SM; von Wasielewski R; Werner M; Dirks WG
    Leukemia; 2000 Sep; 14(9):1533-59. PubMed ID: 10994999
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.
    Voena C; Conte C; Ambrogio C; Boeri Erba E; Boccalatte F; Mohammed S; Jensen ON; Palestro G; Inghirami G; Chiarle R
    Cancer Res; 2007 May; 67(9):4278-86. PubMed ID: 17483340
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma.
    Hamedani FS; Cinar M; Mo Z; Cervania MA; Amin HM; Alkan S
    Leuk Res; 2014 Apr; 38(4):503-8. PubMed ID: 24486291
    [TBL] [Abstract][Full Text] [Related]  

  • 24. De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.
    Babin L; Darchen A; Robert E; Aid Z; Borry R; Soudais C; Piganeau M; De Cian A; Giovannangeli C; Bawa O; Rigaud C; Scoazec JY; Couronné L; Veleanu L; Cieslak A; Asnafi V; Sibon D; Lamant L; Meggetto F; Mercher T; Brunet E
    Mol Cancer; 2022 Mar; 21(1):65. PubMed ID: 35246138
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Precision therapy with anaplastic lymphoma kinase inhibitor ceritinib in ALK-rearranged anaplastic large cell lymphoma.
    Subbiah V; Kuravi S; Ganguly S; Welch DR; Vivian CJ; Mushtaq MU; Hegde A; Iyer S; Behrang A; Ali SM; Madison RW; Venstrom JM; Jensen RA; McGuirk JP; Amin HM; Balusu R
    ESMO Open; 2021 Aug; 6(4):100172. PubMed ID: 34242968
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular characterization of the t(2;5) (p23; q35) translocation in anaplastic large cell lymphoma (Ki-1) and Hodgkin's disease.
    Yee HT; Ponzoni M; Merson A; Goldstein M; Scarpa A; Chilosi M; Menestrina F; Pittaluga S; de Wolf-Peeters C; Shiota M; Mori S; Frizzera G; Inghirami G
    Blood; 1996 Feb; 87(3):1081-8. PubMed ID: 8562933
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Activation of IGF-1R pathway and NPM-ALK G1269A mutation confer resistance to crizotinib treatment in NPM-ALK positive lymphoma.
    Li Y; Wang K; Song N; Hou K; Che X; Zhou Y; Liu Y; Zhang J
    Invest New Drugs; 2020 Jun; 38(3):599-609. PubMed ID: 31177400
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of a novel crosstalk between casein kinase 2α and NPM-ALK in ALK-positive anaplastic large cell lymphoma.
    Armanious H; Gelebart P; Anand M; Lai R
    Cell Signal; 2013 Feb; 25(2):381-8. PubMed ID: 23153582
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Hammerhead ribozyme-mediated cleavage of the fusion transcript NPM-ALK associated with anaplastic large-cell lymphoma.
    Hübinger G; Wehnes E; Xue L; Morris SW; Maurer U
    Exp Hematol; 2003 Mar; 31(3):226-33. PubMed ID: 12644020
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The ALK inhibitor ASP3026 eradicates NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model.
    George SK; Vishwamitra D; Manshouri R; Shi P; Amin HM
    Oncotarget; 2014 Jul; 5(14):5750-63. PubMed ID: 25026277
    [TBL] [Abstract][Full Text] [Related]  

  • 31. IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.
    Shi P; Lai R; Lin Q; Iqbal AS; Young LC; Kwak LW; Ford RJ; Amin HM
    Blood; 2009 Jul; 114(2):360-70. PubMed ID: 19423729
    [TBL] [Abstract][Full Text] [Related]  

  • 32. NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair.
    Bone KM; Wang P; Wu F; Wu C; Li L; Bacani JT; Andrew SE; Lai R
    Blood Cancer J; 2015 May; 5(5):e311. PubMed ID: 25978431
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The t(2;5) in human lymphomas.
    Kadin ME; Morris SW
    Leuk Lymphoma; 1998 Apr; 29(3-4):249-56. PubMed ID: 9684923
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Methotrexate significantly induces apoptosis by inhibiting STAT3 activation in NPM-ALK-positive ALCL cells.
    Uchihara Y; Komori R; Tago K; Tamura H; Funakoshi-Tago M
    Biochem Pharmacol; 2019 Dec; 170():113666. PubMed ID: 31654627
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma.
    Fuchs S; Naderi J; Meggetto F
    Int J Mol Sci; 2019 Apr; 20(9):. PubMed ID: 31052302
    [TBL] [Abstract][Full Text] [Related]  

  • 36. ALK kinase domain mutations in primary anaplastic large cell lymphoma: consequences on NPM-ALK activity and sensitivity to tyrosine kinase inhibitors.
    Lovisa F; Cozza G; Cristiani A; Cuzzolin A; Albiero A; Mussolin L; Pillon M; Moro S; Basso G; Rosolen A; Bonvini P
    PLoS One; 2015; 10(4):e0121378. PubMed ID: 25874976
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway.
    Bai RY; Ouyang T; Miething C; Morris SW; Peschel C; Duyster J
    Blood; 2000 Dec; 96(13):4319-27. PubMed ID: 11110708
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein.
    Young LC; Bone KM; Wang P; Wu F; Adam BA; Hegazy S; Gelebart P; Holovati J; Li L; Andrew SE; Lai R
    Am J Pathol; 2011 Jul; 179(1):411-21. PubMed ID: 21703420
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma.
    Wu C; Zhang HF; Gupta N; Alshareef A; Wang Q; Huang YH; Lewis JT; Douglas DN; Kneteman NM; Lai R
    J Hematol Oncol; 2016 Nov; 9(1):120. PubMed ID: 27821172
    [TBL] [Abstract][Full Text] [Related]  

  • 40. BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL.
    Garland GD; Ducray SP; Jahangiri L; Pucci P; Amos Burke GA; Monahan J; Lai R; Merkel O; Schiefer AI; Kenner L; Bannister AJ; Turner SD
    Cancers (Basel); 2021 Dec; 14(1):. PubMed ID: 35008316
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.