205 related articles for article (PubMed ID: 37765003)
1. Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole- and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer's Disease.
Angelova VT; Georgiev B; Pencheva T; Pajeva I; Rangelov M; Todorova N; Zheleva-Dimitrova D; Kalcheva-Yovkova E; Valkova IV; Vassilev N; Mihaylova R; Stefanova D; Petrov B; Voynikov Y; Tzankova V
Pharmaceuticals (Basel); 2023 Aug; 16(9):. PubMed ID: 37765003
[TBL] [Abstract][Full Text] [Related]
2. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors:
Makhaeva GF; Kovaleva NV; Boltneva NP; Rudakova EV; Lushchekina SV; Astakhova TY; Serkov IV; Proshin AN; Radchenko EV; Palyulin VA; Korabecny J; Soukup O; Bachurin SO; Richardson RJ
Molecules; 2022 Feb; 27(3):. PubMed ID: 35164325
[TBL] [Abstract][Full Text] [Related]
3. Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease.
Brunetti L; Leuci R; Carrieri A; Catto M; Occhineri S; Vinci G; Gambacorta L; Baltrukevich H; Chaves S; Laghezza A; Altomare CD; Tortorella P; Santos MA; Loiodice F; Piemontese L
Eur J Med Chem; 2022 Jul; 237():114358. PubMed ID: 35462163
[TBL] [Abstract][Full Text] [Related]
4. Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.
Manzoor S; Prajapati SK; Majumdar S; Raza MK; Gabr MT; Kumar S; Pal K; Rashid H; Kumar S; Krishnamurthy S; Hoda N
Eur J Med Chem; 2021 Apr; 215():113224. PubMed ID: 33582578
[TBL] [Abstract][Full Text] [Related]
5. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.
Singh YP; Shankar G; Jahan S; Singh G; Kumar N; Barik A; Upadhyay P; Singh L; Kamble K; Singh GK; Tiwari S; Garg P; Gupta S; Modi G
Bioorg Med Chem; 2021 Sep; 46():116385. PubMed ID: 34481338
[TBL] [Abstract][Full Text] [Related]
6. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
Makhaeva GF; Lushchekina SV; Kovaleva NV; Yu Astakhova T; Boltneva NP; Rudakova EV; Serebryakova OG; Proshin AN; Serkov IV; Trofimova TP; Tafeenko VA; Radchenko EV; Palyulin VA; Fisenko VP; Korábečný J; Soukup O; Richardson RJ
Bioorg Chem; 2021 Jul; 112():104974. PubMed ID: 34029971
[TBL] [Abstract][Full Text] [Related]
7. Design, Synthesis, and Biological Evaluation of Piperazine and
Waiker DK; Verma A; Akhilesh ; A GT; Singh N; Roy A; Dilnashin H; Tiwari V; Trigun SK; Singh SP; Krishnamurthy S; Lama P; Davisson VJ; Shrivastava SK
ACS Chem Neurosci; 2023 Jun; 14(11):2217-2242. PubMed ID: 37216500
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Macedo Vaz S; de Freitas Silva M; Dos Reis Rosa Franco G; Jorge R Guimarães M; Motta R da Silva F; Gonçalves Castro N; Alvim Guedes I; Dardenne LE; Amaral Alves M; Garrett da Costa R; Beserra Pinheiro G; Germino Veras L; Renata Mortari M; Pruccoli L; Tarozzi A; Viegas C
Bioorg Med Chem; 2022 Oct; 71():116952. PubMed ID: 35930852
[TBL] [Abstract][Full Text] [Related]
9. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
Cai P; Fang SQ; Yang HL; Yang XL; Liu QH; Kong LY; Wang XB
Eur J Med Chem; 2018 Sep; 157():161-176. PubMed ID: 30096650
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and molecular docking and ADME studies of novel hydrazone derivatives for AChE inhibitory, BBB permeability and antioxidant effects.
Osmaniye D; Ahmad I; Sağlık BN; Levent S; Patel HM; Ozkay Y; Kaplancıklı ZA
J Biomol Struct Dyn; 2023; 41(18):9022-9038. PubMed ID: 36325982
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J; Gallardo-Garrido C; Mallea M; Bustos V; Osorio R; Hödar-Salazar M; Chung H; Araya-Maturana R; Lorca M; Pessoa-Mahana CD; Mella-Raipán J; Saitz C; Jaque P; Reyes-Parada M; Iturriaga-Vásquez P; Pessoa-Mahana H
Eur J Med Chem; 2020 Jul; 198():112368. PubMed ID: 32388114
[TBL] [Abstract][Full Text] [Related]
13. Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
Makhaeva GF; Kovaleva NV; Rudakova EV; Boltneva NP; Grishchenko MV; Lushchekina SV; Astakhova TY; Serebryakova OG; Timokhina EN; Zhilina EF; Shchegolkov EV; Ulitko MV; Radchenko EV; Palyulin VA; Burgart YV; Saloutin VI; Bachurin SO; Richardson RJ
Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768608
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.
Mishra CB; Kumari S; Manral A; Prakash A; Saini V; Lynn AM; Tiwari M
Eur J Med Chem; 2017 Jan; 125():736-750. PubMed ID: 27721157
[TBL] [Abstract][Full Text] [Related]
15. Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease.
Carocci A; Barbarossa A; Leuci R; Carrieri A; Brunetti L; Laghezza A; Catto M; Limongelli F; Chaves S; Tortorella P; Altomare CD; Santos MA; Loiodice F; Piemontese L
Antioxidants (Basel); 2022 Aug; 11(9):. PubMed ID: 36139705
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, crystal structure,
Kausar N; Murtaza S; Arshad MN; Zaib Saleem RS; Asiri AM; Kausar S; Altaf AA; Tatheer A; Elnaggar AY; El-Bahy SM
RSC Adv; 2021 Dec; 12(1):154-167. PubMed ID: 35424495
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease.
Eissa KI; Kamel MM; Mohamed LW; Doghish AS; Alnajjar R; Al-Karmalawy AA; Kassab AE
Drug Dev Res; 2023 Aug; 84(5):937-961. PubMed ID: 37067008
[TBL] [Abstract][Full Text] [Related]
18. Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Ortiz CJC; Damasio CM; Pruccoli L; Nadur NF; de Azevedo LL; Guedes IA; Dardenne LE; Kümmerle AE; Tarozzi A; Viegas C
Neurochem Res; 2020 Dec; 45(12):3003-3020. PubMed ID: 33079324
[TBL] [Abstract][Full Text] [Related]
19. Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer's disease: Quinolotacrine hybrids.
Sadafi Kohnehshahri M; Chehardoli G; Bahiraei M; Akbarzadeh T; Ranjbar A; Rastegari A; Najafi Z
Mol Divers; 2022 Feb; 26(1):489-503. PubMed ID: 34491490
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Sang Z; Pan W; Wang K; Ma Q; Yu L; Yang Y; Bai P; Leng C; Xu Q; Li X; Tan Z; Liu W
Eur J Med Chem; 2017 Apr; 130():379-392. PubMed ID: 28279845
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]