BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 37767768)

  • 1. Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.
    Welsh SJ; Barwick BG; Meermeier EW; Riggs DL; Shi CX; Zhu YX; Sharik ME; Du MT; Abrego Rocha LD; Garbitt VM; Stein CK; Petit JL; Meurice N; Tafoya Alvarado Y; Fonseca R; Todd KT; Brown S; Hammond ZJ; Cuc NH; Wittenberg C; Herzog C; Roschke AV; Demchenko YN; Chen WD; Li P; Liao W; Leonard WJ; Lonial S; Bahlis NJ; Neri P; Boise LH; Chesi M; Bergsagel PL
    Blood Cancer Discov; 2024 Jan; 5(1):34-55. PubMed ID: 37767768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.
    Neri P; Barwick BG; Jung D; Patton JC; Maity R; Tagoug I; Stein CK; Tilmont R; Leblay N; Ahn S; Lee H; Welsh SJ; Riggs DL; Stong N; Flynt E; Thakurta A; Keats JJ; Lonial S; Bergsagel PL; Boise LH; Bahlis NJ
    Blood Cancer Discov; 2024 Jan; 5(1):56-73. PubMed ID: 37934799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional Plasticity Drives IMiD and p300 Inhibitor Resistance in Multiple Myeloma.
    Yun S; Cleveland JL
    Blood Cancer Discov; 2024 Jan; 5(1):5-7. PubMed ID: 38085608
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma.
    Patil A; Manzano M; Gottwein E
    Blood; 2018 Aug; 132(6):577-586. PubMed ID: 29954751
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma.
    Osada N; Kikuchi J; Iha H; Yasui H; Ikeda S; Takahashi N; Furukawa Y
    Clin Transl Med; 2023 Aug; 13(8):e1364. PubMed ID: 37581569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of immunomodulatory drug resistance and novel therapeutic strategies in multiple myeloma.
    Zuo X; Liu D
    Hematology; 2022 Dec; 27(1):1110-1121. PubMed ID: 36121114
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MYC Inhibition Potentiates CD8+ T Cells Against Multiple Myeloma and Overcomes Immunomodulatory Drug Resistance.
    Davis LN; Walker ZJ; Reiman LT; Parzych SE; Stevens BM; Jordan CT; Forsberg PA; Sherbenou DW
    Clin Cancer Res; 2024 May; ():. PubMed ID: 38723281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The IKZF1-IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages.
    Mougiakakos D; Bach C; Böttcher M; Beier F; Röhner L; Stoll A; Rehli M; Gebhard C; Lischer C; Eberhardt M; Vera J; Büttner-Herold M; Bitterer K; Balzer H; Leffler M; Jitschin S; Hundemer M; Awwad MHS; Busch M; Stenger S; Völkl S; Schütz C; Krönke J; Mackensen A; Bruns H
    Cancer Immunol Res; 2021 Mar; 9(3):265-278. PubMed ID: 33563611
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4.
    Zhu YX; Shi CX; Bruins LA; Wang X; Riggs DL; Porter B; Ahmann JM; de Campos CB; Braggio E; Bergsagel PL; Stewart AK
    Blood Cancer J; 2019 Feb; 9(2):19. PubMed ID: 30741931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation of a lenalidomide-sensitive syngeneic murine in vivo multiple myeloma model by expression of Crbn
    Röhner L; Ng YLD; Scheffold A; Lindner S; Köpff S; Brandl A; Beilhack A; Krönke J
    Exp Hematol; 2021 Jan; 93():61-69.e4. PubMed ID: 33186626
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation.
    Zhou N; Gutierrez-Uzquiza A; Zheng XY; Chang R; Vogl DT; Garfall AL; Bernabei L; Saraf A; Florens L; Washburn MP; Illendula A; Bushweller JH; Busino L
    Leukemia; 2019 Aug; 33(8):2006-2021. PubMed ID: 30760870
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma.
    Dimopoulos K; Fibiger Munch-Petersen H; Winther Eskelund C; Dissing Sjö L; Ralfkiaer E; Gimsing P; Grønbaek K
    Leuk Lymphoma; 2019 Jan; 60(1):180-188. PubMed ID: 29718735
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Durvalumab Combined with Immunomodulatory Drugs (IMiD) Overcomes Suppression of Antitumor Responses due to IMiD-induced PD-L1 Upregulation on Myeloma Cells.
    Ishibashi M; Yamamoto J; Ito T; Handa H; Sunakawa-Kii M; Inokuchi K; Morita R; Tamura H
    Mol Cancer Ther; 2021 Jul; 20(7):1283-1294. PubMed ID: 33879556
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors.
    Gopalakrishnan R; Matta H; Tolani B; Triche T; Chaudhary PM
    Oncogene; 2016 Apr; 35(14):1797-810. PubMed ID: 26119939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploiting Protein Translation Dependence in Multiple Myeloma with Omacetaxine-Based Therapy.
    Walker ZJ; Idler BM; Davis LN; Stevens BM; VanWyngarden MJ; Ohlstrom D; Bearrows SC; Hammes A; Smith CA; Jordan CT; Mark TM; Forsberg PA; Sherbenou DW
    Clin Cancer Res; 2021 Feb; 27(3):819-830. PubMed ID: 33109736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of Label-Free Impedimetric Immunosensors for IKZF1 and IKZF3 Femtomolar Detection for Monitoring Multiple Myeloma Patients Treated with Lenalidomide.
    Abdulkarim H; Zourob M; Siaj M
    Sci Rep; 2020 Jun; 10(1):10424. PubMed ID: 32591583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pan-PIM kinase inhibitors enhance Lenalidomide's anti-myeloma activity via cereblon-IKZF1/3 cascade.
    Zheng J; Sha Y; Roof L; Foreman O; Lazarchick J; Venkta JK; Kozlowski C; Gasparetto C; Chao N; Ebens A; Hu J; Kang Y
    Cancer Lett; 2019 Jan; 440-441():1-10. PubMed ID: 30312729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4.
    Bjorklund CC; Lu L; Kang J; Hagner PR; Havens CG; Amatangelo M; Wang M; Ren Y; Couto S; Breider M; Ning Y; Gandhi AK; Daniel TO; Chopra R; Klippel A; Thakurta AG
    Blood Cancer J; 2015 Oct; 5(10):e354. PubMed ID: 26430725
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IMiD resistance in multiple myeloma: current understanding of the underpinning biology and clinical impact.
    Bird S; Pawlyn C
    Blood; 2023 Jul; 142(2):131-140. PubMed ID: 36929172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation.
    Yamanaka S; Furihata H; Yanagihara Y; Taya A; Nagasaka T; Usui M; Nagaoka K; Shoya Y; Nishino K; Yoshida S; Kosako H; Tanokura M; Miyakawa T; Imai Y; Shibata N; Sawasaki T
    Nat Commun; 2023 Aug; 14(1):4683. PubMed ID: 37596276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.