126 related articles for article (PubMed ID: 37770316)
1. Harnessing UBR5 for targeted protein degradation of key transcriptional regulators.
Taherbhoy AM; Daniels DL
Trends Pharmacol Sci; 2023 Nov; 44(11):758-761. PubMed ID: 37770316
[TBL] [Abstract][Full Text] [Related]
2. Modulation of myocardin function by the ubiquitin E3 ligase UBR5.
Hu G; Wang X; Saunders DN; Henderson M; Russell AJ; Herring BP; Zhou J
J Biol Chem; 2010 Apr; 285(16):11800-9. PubMed ID: 20167605
[TBL] [Abstract][Full Text] [Related]
3. Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.
Schukur L; Zimmermann T; Niewoehner O; Kerr G; Gleim S; Bauer-Probst B; Knapp B; Galli GG; Liang X; Mendiola A; Reece-Hoyes J; Rapti M; Barbosa I; Reschke M; Radimerski T; Thoma CR
Sci Rep; 2020 Nov; 10(1):20044. PubMed ID: 33208877
[TBL] [Abstract][Full Text] [Related]
4. Ligandability of E3 Ligases for Targeted Protein Degradation Applications.
Belcher BP; Ward CC; Nomura DK
Biochemistry; 2023 Feb; 62(3):588-600. PubMed ID: 34473924
[TBL] [Abstract][Full Text] [Related]
5. Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
Hodáková Z; Grishkovskaya I; Brunner HL; Bolhuis DL; Belačić K; Schleiffer A; Kotisch H; Brown NG; Haselbach D
EMBO J; 2023 Aug; 42(16):e113348. PubMed ID: 37409633
[TBL] [Abstract][Full Text] [Related]
6. UBR5 Acts as an Antiviral Host Factor against MERS-CoV via Promoting Ubiquitination and Degradation of ORF4b.
Zhou Y; Zheng R; Liu D; Liu S; Disoma C; Li S; Liao Y; Chen Z; Du A; Dong Z; Zhang Y; Liu P; Razzaq A; Chen D; Chen X; Zhong X; Liu S; Tao S; Liu Y; Xu L; Deng X; Li J; Jiang T; Zhao J; Li S; Xia Z
J Virol; 2022 Sep; 96(17):e0074122. PubMed ID: 35980206
[TBL] [Abstract][Full Text] [Related]
7. The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.
Muñoz-Escobar J; Matta-Camacho E; Kozlov G; Gehring K
J Biol Chem; 2015 Sep; 290(37):22841-50. PubMed ID: 26224628
[TBL] [Abstract][Full Text] [Related]
8. UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Tsai JM; Aguirre JD; Li YD; Brown J; Focht V; Kater L; Kempf G; Sandoval B; Schmitt S; Rutter JC; Galli P; Sandate CR; Cutler JA; Zou C; Donovan KA; Lumpkin RJ; Cavadini S; Park PMC; Sievers Q; Hatton C; Ener E; Regalado BD; Sperling MT; Słabicki M; Kim J; Zon R; Zhang Z; Miller PG; Belizaire R; Sperling AS; Fischer ES; Irizarry R; Armstrong SA; Thomä NH; Ebert BL
Mol Cell; 2023 Aug; 83(15):2753-2767.e10. PubMed ID: 37478846
[TBL] [Abstract][Full Text] [Related]
9. Characterization of interaction and ubiquitination of phosphoenolpyruvate carboxykinase by E3 ligase UBR5.
Shen Q; Qiu Z; Wu W; Zheng J; Jia Z
Biol Open; 2018 Dec; 7(12):. PubMed ID: 30552140
[TBL] [Abstract][Full Text] [Related]
10. UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy.
Seaborne RA; Hughes DC; Turner DC; Owens DJ; Baehr LM; Gorski P; Semenova EA; Borisov OV; Larin AK; Popov DV; Generozov EV; Sutherland H; Ahmetov II; Jarvis JC; Bodine SC; Sharples AP
J Physiol; 2019 Jul; 597(14):3727-3749. PubMed ID: 31093990
[TBL] [Abstract][Full Text] [Related]
11. To be (in a transcriptional complex) or not to be (promoting UBR5 ubiquitylation): That is an answer to how degradation controls gene expression.
Hehl LA; Schulman BA
Mol Cell; 2023 Aug; 83(15):2616-2618. PubMed ID: 37541216
[TBL] [Abstract][Full Text] [Related]
12. Hijacking Methyl Reader Proteins for Nuclear-Specific Protein Degradation.
Nalawansha DA; Li K; Hines J; Crews CM
J Am Chem Soc; 2022 Mar; 144(12):5594-5605. PubMed ID: 35311258
[TBL] [Abstract][Full Text] [Related]
13. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin.
Matsuura K; Huang NJ; Cocce K; Zhang L; Kornbluth S
Oncogene; 2017 Mar; 36(12):1698-1706. PubMed ID: 27721409
[TBL] [Abstract][Full Text] [Related]
14. Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy.
Liu TT; Yang H; Zhuo FF; Yang Z; Zhao MM; Guo Q; Liu Y; Liu D; Zeng KW; Tu PF
EBioMedicine; 2022 Dec; 86():104353. PubMed ID: 36375317
[TBL] [Abstract][Full Text] [Related]
15. Structure of the human UBR5 E3 ubiquitin ligase.
Wang F; He Q; Zhan W; Yu Z; Finkin-Groner E; Ma X; Lin G; Li H
Structure; 2023 May; 31(5):541-552.e4. PubMed ID: 37040767
[TBL] [Abstract][Full Text] [Related]
16. [Induced degradation of proteins by PROTACs and other strategies: towards promising drugs].
Reboud-Ravaux M
Biol Aujourdhui; 2021; 215(1-2):25-43. PubMed ID: 34397373
[TBL] [Abstract][Full Text] [Related]
17. VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases.
Nakagawa T; Mondal K; Swanson PC
BMC Mol Biol; 2013 Sep; 14():22. PubMed ID: 24028781
[TBL] [Abstract][Full Text] [Related]
18. Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities
Singh S; Ng J; Nayak D; Sivaraman J
J Biol Chem; 2019 Dec; 294(52):19934-19949. PubMed ID: 31732561
[TBL] [Abstract][Full Text] [Related]
19. Emerging roles of the HECT E3 ubiquitin ligases in gastric cancer.
Sun A; Tian X; Chen Y; Yang W; Lin Q
Pathol Oncol Res; 2023; 29():1610931. PubMed ID: 36825281
[TBL] [Abstract][Full Text] [Related]
20. Building ubiquitination machineries: E3 ligase multi-subunit assembly and substrate targeting by PROTACs and molecular glues.
Ramachandran S; Ciulli A
Curr Opin Struct Biol; 2021 Apr; 67():110-119. PubMed ID: 33271439
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]