184 related articles for article (PubMed ID: 37777536)
1. PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development.
Lau HH; Krentz NAJ; Abaitua F; Perez-Alcantara M; Chan JW; Ajeian J; Ghosh S; Lee Y; Yang J; Thaman S; Champon B; Sun H; Jha A; Hoon S; Tan NS; Gardner DS; Kao SL; Tai ES; Gloyn AL; Teo AKK
Nat Commun; 2023 Sep; 14(1):6119. PubMed ID: 37777536
[TBL] [Abstract][Full Text] [Related]
2. PAX4 R192H and P321H polymorphisms in type 2 diabetes and their functional defects.
Sujjitjoon J; Kooptiwut S; Chongjaroen N; Semprasert N; Hanchang W; Chanprasert K; Tangjittipokin W; Yenchitsomanus PT; Plengvidhya N
J Hum Genet; 2016 Nov; 61(11):943-949. PubMed ID: 27334367
[TBL] [Abstract][Full Text] [Related]
3. Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.
Mattis KK; Krentz NAJ; Metzendorf C; Abaitua F; Spigelman AF; Sun H; Ikle JM; Thaman S; Rottner AK; Bautista A; Mazzaferro E; Perez-Alcantara M; Manning Fox JE; Torres JM; Wesolowska-Andersen A; Yu GZ; Mahajan A; Larsson A; MacDonald PE; Davies B; den Hoed M; Gloyn AL
Diabetologia; 2023 Apr; 66(4):674-694. PubMed ID: 36633628
[TBL] [Abstract][Full Text] [Related]
4. The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.
Brun T; Hu He KH; Lupi R; Boehm B; Wojtusciszyn A; Sauter N; Donath M; Marchetti P; Maedler K; Gauthier BR
Hum Mol Genet; 2008 Feb; 17(4):478-89. PubMed ID: 17989064
[TBL] [Abstract][Full Text] [Related]
5. Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression.
Djiotsa J; Verbruggen V; Giacomotto J; Ishibashi M; Manning E; Rinkwitz S; Manfroid I; Voz ML; Peers B
BMC Dev Biol; 2012 Dec; 12():37. PubMed ID: 23244389
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of PAX4 reduces glucagon expression in differentiating hESCs.
Gage BK; Baker RK; Kieffer TJ
Islets; 2014; 6(2):e29236. PubMed ID: 25483960
[TBL] [Abstract][Full Text] [Related]
7. PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment.
Zhang Y; Fava GE; Wang H; Mauvais-Jarvis F; Fonseca VA; Wu H
Mol Ther; 2016 Feb; 24(2):251-260. PubMed ID: 26435408
[TBL] [Abstract][Full Text] [Related]
8. Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.
Bonnavion R; Jaafar R; Kerr-Conte J; Assade F; van Stralen E; Leteurtre E; Pouponnot C; Gargani S; Pattou F; Bertolino P; Cordier-Bussat M; Lu J; Zhang CX
PLoS One; 2013; 8(8):e72194. PubMed ID: 24013263
[TBL] [Abstract][Full Text] [Related]
9. Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes.
Kooptiwut S; Plengvidhya N; Chukijrungroat T; Sujjitjoon J; Semprasert N; Furuta H; Yenchitsomanus PT
J Diabetes Complications; 2012; 26(4):343-7. PubMed ID: 22521316
[TBL] [Abstract][Full Text] [Related]
10. Aberrant mRNA splicing of paired box 4 (PAX4) IVS7-1G>A mutation causing maturity-onset diabetes of the young, type 9.
Sujjitjoon J; Kooptiwut S; Chongjaroen N; Tangjittipokin W; Plengvidhya N; Yenchitsomanus PT
Acta Diabetol; 2016 Apr; 53(2):205-16. PubMed ID: 25951767
[TBL] [Abstract][Full Text] [Related]
11. Pax4 Gene Delivery Improves Islet Transplantation Efficacy by Promoting β Cell Survival and α-to-β Cell Transdifferentiation.
Parajuli KR; Zhang Y; Cao AM; Wang H; Fonseca VA; Wu H
Cell Transplant; 2020; 29():963689720958655. PubMed ID: 33086892
[TBL] [Abstract][Full Text] [Related]
12. Nonsynonymous Variants in
Kwak SH; Chae J; Lee S; Choi S; Koo BK; Yoon JW; Park JH; Cho B; Moon MK; Lim S; Cho YM; Moon S; Kim YJ; Han S; Hwang MY; Cho YS; Lee MS; Jang HC; Kang HM; Park T; Cho NH; Kim K; Kim JI; Park KS
Diabetes; 2018 Sep; 67(9):1892-1902. PubMed ID: 29941447
[TBL] [Abstract][Full Text] [Related]
13. In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.
Hu He KH; Lorenzo PI; Brun T; Jimenez Moreno CM; Aeberhard D; Vallejo Ortega J; Cornu M; Thorel F; Gjinovci A; Thorens B; Herrera PL; Meda P; Wollheim CB; Gauthier BR
Diabetes; 2011 Jun; 60(6):1705-15. PubMed ID: 21521872
[TBL] [Abstract][Full Text] [Related]
14. PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.
Lorenzo PI; Fuente-Martín E; Brun T; Cobo-Vuilleumier N; Jimenez-Moreno CM; G Herrera Gomez I; López Noriega L; Mellado-Gil JM; Martin-Montalvo A; Soria B; Gauthier BR
Sci Rep; 2015 Oct; 5():15672. PubMed ID: 26503027
[TBL] [Abstract][Full Text] [Related]
15. PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
Mellado-Gil JM; Jiménez-Moreno CM; Martin-Montalvo A; Alvarez-Mercado AI; Fuente-Martin E; Cobo-Vuilleumier N; Lorenzo PI; Bru-Tari E; Herrera-Gómez Ide G; López-Noriega L; Pérez-Florido J; Santoyo-López J; Spyrantis A; Meda P; Boehm BO; Quesada I; Gauthier BR
Diabetologia; 2016 Apr; 59(4):755-65. PubMed ID: 26813254
[TBL] [Abstract][Full Text] [Related]
16. Pax4 in Health and Diabetes.
Ko J; Fonseca VA; Wu H
Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37175989
[TBL] [Abstract][Full Text] [Related]
17. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.
Kulzer JR; Stitzel ML; Morken MA; Huyghe JR; Fuchsberger C; Kuusisto J; Laakso M; Boehnke M; Collins FS; Mohlke KL
Am J Hum Genet; 2014 Feb; 94(2):186-97. PubMed ID: 24439111
[TBL] [Abstract][Full Text] [Related]
18. The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus.
Tokuyama Y; Matsui K; Ishizuka T; Egashira T; Kanatsuka A
Metabolism; 2006 Feb; 55(2):213-6. PubMed ID: 16423628
[TBL] [Abstract][Full Text] [Related]
19. The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.
Mellado-Gil JM; Fuente-Martín E; Lorenzo PI; Cobo-Vuilleumier N; López-Noriega L; Martín-Montalvo A; Gómez IGH; Ceballos-Chávez M; Gómez-Jaramillo L; Campos-Caro A; Romero-Zerbo SY; Rodríguez-Comas J; Servitja JM; Rojo-Martinez G; Hmadcha A; Soria B; Bugliani M; Marchetti P; Bérmudez-Silva FJ; Reyes JC; Aguilar-Diosdado M; Gauthier BR
Cell Death Dis; 2018 Feb; 9(3):279. PubMed ID: 29449530
[TBL] [Abstract][Full Text] [Related]
20. A novel PAX4 mutation in a Japanese patient with maturity-onset diabetes of the young.
Jo W; Endo M; Ishizu K; Nakamura A; Tajima T
Tohoku J Exp Med; 2011 Feb; 223(2):113-8. PubMed ID: 21263211
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
