BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 37781951)

  • 1. Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth.
    Nakahara R; Aki S; Sugaya M; Hirose H; Kato M; Maeda K; Sakamoto DM; Kojima Y; Nishida M; Ando R; Muramatsu M; Pan M; Tsuchida R; Matsumura Y; Yanai H; Takano H; Yao R; Sando S; Shibuya M; Sakai J; Kodama T; Kidoya H; Shimamura T; Osawa T
    EMBO J; 2023 Nov; 42(22):e114032. PubMed ID: 37781951
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.
    Kuan YC; Takahashi Y; Maruyama T; Shimizu M; Yamauchi Y; Sato R
    J Biol Chem; 2020 Mar; 295(12):3918-3928. PubMed ID: 32054686
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.
    Guo C; Chi Z; Jiang D; Xu T; Yu W; Wang Z; Chen S; Zhang L; Liu Q; Guo X; Zhang X; Li W; Lu L; Wu Y; Song BL; Wang D
    Immunity; 2018 Nov; 49(5):842-856.e7. PubMed ID: 30366764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Leishmania donovani activates SREBP2 to modulate macrophage membrane cholesterol and mitochondrial oxidants for establishment of infection.
    Mukherjee M; Basu Ball W; Das PK
    Int J Biochem Cell Biol; 2014 Oct; 55():196-208. PubMed ID: 25218172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation.
    Li LC; Varghese Z; Moorhead JF; Lee CT; Chen JB; Ruan XZ
    Am J Physiol Heart Circ Physiol; 2013 Mar; 304(6):H874-84. PubMed ID: 23335792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis.
    Dickson AS; Pauzaite T; Arnaiz E; Ortmann BM; West JA; Volkmar N; Martinelli AW; Li Z; Wit N; Vitkup D; Kaser A; Lehner PJ; Nathan JA
    Nat Commun; 2023 Aug; 14(1):4816. PubMed ID: 37558666
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unspliced XBP1 contributes to cholesterol biosynthesis and tumorigenesis by stabilizing SREBP2 in hepatocellular carcinoma.
    Wei M; Nurjanah U; Herkilini A; Huang C; Li Y; Miyagishi M; Wu S; Kasim V
    Cell Mol Life Sci; 2022 Aug; 79(9):472. PubMed ID: 35933495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis.
    Kober DL; Xu S; Li S; Bajaj B; Liang G; Rosenbaum DM; Radhakrishnan A
    Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28080-28091. PubMed ID: 33106423
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.
    Kondo A; Yamamoto S; Nakaki R; Shimamura T; Hamakubo T; Sakai J; Kodama T; Yoshida T; Aburatani H; Osawa T
    Cell Rep; 2017 Feb; 18(9):2228-2242. PubMed ID: 28249167
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.
    Gu D; Zhou F; You H; Gao J; Kang T; Dixit D; Wu Q; Yang K; Ci S; Shan D; Fan X; Yuan W; Zhang Q; Lu C; Li D; Zhao N; Shi Z; Gao W; Lin F; Man J; Wang Q; Qian X; Mack SC; Tao W; Agnihotri S; Zhang N; You Y; Rich JN; Zhang J; Wang X
    Neuro Oncol; 2023 Sep; 25(9):1578-1591. PubMed ID: 36934350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dietary palm oil enhances Sterol regulatory element-binding protein 2-mediated cholesterol biosynthesis through inducing endoplasmic reticulum stress in muscle of large yellow croaker (
    Zhao Z; Li B; Chen Q; Xiang X; Xu X; Han S; Lai W; Li Y; Xu W; Mai K; Ai Q
    Br J Nutr; 2024 Feb; 131(4):553-566. PubMed ID: 37699661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis.
    Gopoju R; Panangipalli S; Kotamraju S
    Free Radic Biol Med; 2018 Apr; 118():85-97. PubMed ID: 29499335
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Difference in LDL receptor feedback regulation in macrophages and vascular smooth muscle cells: foam cell transformation under inflammatory stress.
    Ye Q; Lei H; Fan Z; Zheng W; Zheng S
    Inflammation; 2014 Apr; 37(2):555-65. PubMed ID: 24297394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epithelial Cholesterol Deficiency Attenuates Human Antigen R-linked Pro-inflammatory Stimulation via an SREBP2-linked Circuit.
    Park SH; Kim J; Yu M; Park JH; Kim YS; Moon Y
    J Biol Chem; 2016 Nov; 291(47):24641-24656. PubMed ID: 27703009
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inflammatory stress signaling via NF-
    Fowler JWM; Zhang R; Tao B; Boutagy NE; Sessa WC
    Elife; 2022 Aug; 11():. PubMed ID: 35959888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GPHR-mediated acidification of the Golgi lumen is essential for cholesterol biosynthesis in the brain.
    Sou YS; Yamaguchi J; Kameda H; Masuda K; Maeda Y; Uchiyama Y; Koike M
    FEBS Lett; 2022 Nov; 596(22):2873-2888. PubMed ID: 36056653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.
    Benatzy Y; Palmer MA; Lütjohann D; Ohno RI; Kampschulte N; Schebb NH; Fuhrmann DC; Snodgrass RG; Brüne B
    Redox Biol; 2024 Jun; 72():103149. PubMed ID: 38581859
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbon dioxide regulates cholesterol levels through SREBP2.
    Bolshette N; Ezagouri S; Dandavate V; Karavaeva I; Golik M; Wang H; Espenshade PJ; Osborne TF; Han X; Asher G
    PLoS Biol; 2023 Nov; 21(11):e3002367. PubMed ID: 37967106
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
    Zeng L; Liao H; Liu Y; Lee TS; Zhu M; Wang X; Stemerman MB; Zhu Y; Shyy JY
    J Biol Chem; 2004 Nov; 279(47):48801-7. PubMed ID: 15358760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SREBP2/Rab11s/GLUT1/6 network regulates proliferation and migration of glioblastoma.
    Cheng C; Tu J; Hu Z; Chen Y; Wang Y; Zhang T; Zhang C; Li C; Wang Y; Niu C
    Pathol Res Pract; 2022 Dec; 240():154176. PubMed ID: 36327817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.