BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 3778522)

  • 1. Morpholino derivatives of benzyl-benzodioxole, a study of structural requirements for drug interactions at the colchicine/podophyllotoxin binding site of tubulin.
    Batra JK; Jurd L; Hamel E
    Biochem Pharmacol; 1986 Nov; 35(22):4013-8. PubMed ID: 3778522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
    Batra JK; Jurd L; Hamel E
    Mol Pharmacol; 1985 Jan; 27(1):94-102. PubMed ID: 3965931
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.
    Batra JK; Kang GJ; Jurd L; Hamel E
    Biochem Pharmacol; 1988 Jul; 37(13):2595-602. PubMed ID: 3390218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effects of 6-benzyl-1,3-benzodioxole derivatives on the alkylation of tubulin.
    Roach MC; Trcka PP; Jurd L; Luduena RF
    Mol Pharmacol; 1987 Sep; 32(3):432-6. PubMed ID: 3670279
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polymerization of tubulin in the presence of colchicine or podophyllotoxin. Formation of a ribbon structure induced by guanylyl-5'-methylene diphosphonate.
    Sandoval IV; Weber K
    J Mol Biol; 1979 Oct; 134(1):159-72. PubMed ID: 537060
    [No Abstract]   [Full Text] [Related]  

  • 7. Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure. Interactions with tubulin.
    Hamel E; Ho HH; Kang GJ; Lin CM
    Biochem Pharmacol; 1988 Jun; 37(12):2445-9. PubMed ID: 3390207
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of inhibitors of tubulin polymerization on GTP hydrolysis.
    Lin CM; Hamel E
    J Biol Chem; 1981 Sep; 256(17):9242-5. PubMed ID: 6114958
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of 2-diazo-3,3,3-trifluopropanoyl derivatives of colchicine and podophyllotoxin as photoaffinity labels: reactivity, photochemistry, and tubulin binding.
    Hahn KM; Hastie SB; Sundberg RJ
    Photochem Photobiol; 1992 Jan; 55(1):17-27. PubMed ID: 1603847
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Lin CM; Ho HH; Pettit GR; Hamel E
    Biochemistry; 1989 Aug; 28(17):6984-91. PubMed ID: 2819042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin.
    Gupta S; Das L; Datta AB; Poddar A; Janik ME; Bhattacharyya B
    Biochemistry; 2006 May; 45(20):6467-75. PubMed ID: 16700557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Correlation of tubulin-binding and antitumor activities of podophyllotoxin analogs.
    Kelleher JK
    Cancer Treat Rep; 1978 Oct; 62(10):1443-7. PubMed ID: 101303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin.
    Sackett DL
    Pharmacol Ther; 1993 Aug; 59(2):163-228. PubMed ID: 8278462
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drugs that inhibit tubulin polymerization: the particular case of podophyllotoxin and analogues.
    Desbène S; Giorgi-Renault S
    Curr Med Chem Anticancer Agents; 2002 Jan; 2(1):71-90. PubMed ID: 12678752
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.
    Batra JK; Powers LJ; Hess FD; Hamel E
    Cancer Res; 1986 Apr; 46(4 Pt 2):1889-93. PubMed ID: 3948171
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
    Lin CM; Kang GJ; Roach MC; Jiang JB; Hesson DP; Luduena RF; Hamel E
    Mol Pharmacol; 1991 Nov; 40(5):827-32. PubMed ID: 1944246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Podophyllotoxin as a probe for the colchicine binding site of tubulin.
    Cortese F; Bhattacharyya B; Wolff J
    J Biol Chem; 1977 Feb; 252(4):1134-40. PubMed ID: 14143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin decay.
    Prasad V; Chaudhuri AR; Curcio M; Tomita I; Mizuhashi F; Murata K; Ludueña RF
    J Protein Chem; 1998 Oct; 17(7):663-8. PubMed ID: 9853681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.
    Zhao W; He L; Xiang TL; Tang YJ
    Eur J Med Chem; 2019 May; 170():73-86. PubMed ID: 30878833
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tubulin binding affinities of podophyllotoxin and colchicine analogues.
    Kelleher JK
    Mol Pharmacol; 1977 Mar; 13(2):232-41. PubMed ID: 854021
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.