BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 37792675)

  • 1. Dynamic ultrasound molecular-targeted imaging of senescence in evaluation of lapatinib resistance in HER2-positive breast cancer.
    Chen X; Li Y; Zhou Z; Zhang Y; Chang L; Gao X; Li Q; Luo H; Westover KD; Zhu J; Wei X
    Cancer Med; 2023 Oct; 12(19):19904-19920. PubMed ID: 37792675
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer.
    Takeda T; Yamamoto H; Kanzaki H; Suzawa K; Yoshioka T; Tomida S; Cui X; Murali R; Namba K; Sato H; Torigoe H; Watanabe M; Shien K; Soh J; Asano H; Tsukuda K; Kitamura Y; Miyoshi S; Sendo T; Toyooka S
    PLoS One; 2017; 12(2):e0171356. PubMed ID: 28158234
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HER3 PET Imaging Identifies Dynamic Changes in HER3 in Response to HER2 Inhibition with Lapatinib.
    Wehrenberg-Klee E; Sinevici N; Nesti S; Kalomeris T; Austin E; Larimer B; Mahmood U
    Mol Imaging Biol; 2021 Dec; 23(6):930-940. PubMed ID: 34101105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lapatinib inhibits doxorubicin induced migration of HER2-positive breast cancer cells.
    Chintalaramulu N; Vadivelu R; Nguyen NT; Cock IE
    Inflammopharmacology; 2020 Oct; 28(5):1375-1386. PubMed ID: 32378049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoproteomic analysis reveals PAK2 as a therapeutic target for lapatinib resistance in HER2-positive breast cancer cells.
    Chang Y; Park KH; Lee JE; Han KC
    Biochem Biophys Res Commun; 2018 Oct; 505(1):187-193. PubMed ID: 30243723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL.
    Eustace AJ; Conlon NT; McDermott MSJ; Browne BC; O'Leary P; Holmes FA; Espina V; Liotta LA; O'Shaughnessy J; Gallagher C; O'Driscoll L; Rani S; Madden SF; O'Brien NA; Ginther C; Slamon D; Walsh N; Gallagher WM; Zagozdzon R; Watson WR; O'Donovan N; Crown J
    BMC Cancer; 2018 Oct; 18(1):965. PubMed ID: 30305055
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CDK12 inhibition enhances sensitivity of HER2+ breast cancers to HER2-tyrosine kinase inhibitor via suppressing PI3K/AKT.
    Li H; Wang J; Yi Z; Li C; Wang H; Zhang J; Wang T; Nan P; Lin F; Xu D; Qian H; Ma F
    Eur J Cancer; 2021 Mar; 145():92-108. PubMed ID: 33429148
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer.
    Sanz-Moreno A; Palomeras S; Pedersen K; Morancho B; Pascual T; Galván P; Benítez S; Gomez-Miragaya J; Ciscar M; Jimenez M; Pernas S; Petit A; Soler-Monsó MT; Viñas G; Alsaleem M; Rakha EA; Green AR; Santamaria PG; Mulder C; Lemeer S; Arribas J; Prat A; Puig T; Gonzalez-Suarez E
    Breast Cancer Res; 2021 Mar; 23(1):42. PubMed ID: 33785053
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the EphB4 receptor tyrosine kinase sensitizes HER2-positive breast cancer cells to Lapatinib.
    Ding J; Yao Y; Huang G; Wang X; Yi J; Zhang N; Liu C; Wang K; Zhang Y; Wang M; Liu P; Ye M; Li M; Cheng H
    Cancer Lett; 2020 Apr; 475():53-64. PubMed ID: 32006616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer.
    Sethunath V; Hu H; De Angelis C; Veeraraghavan J; Qin L; Wang N; Simon LM; Wang T; Fu X; Nardone A; Pereira R; Nanda S; Griffith OL; Tsimelzon A; Shaw C; Chamness GC; Reis-Filho JS; Weigelt B; Heiser LM; Hilsenbeck SG; Huang S; Rimawi MF; Gray JW; Osborne CK; Schiff R
    Mol Cancer Res; 2019 Nov; 17(11):2318-2330. PubMed ID: 31420371
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.
    McDermott MS; Browne BC; Conlon NT; O'Brien NA; Slamon DJ; Henry M; Meleady P; Clynes M; Dowling P; Crown J; O'Donovan N
    Mol Cancer; 2014 Jun; 13():157. PubMed ID: 24958351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies.
    Tracey N; Creedon H; Kemp AJ; Culley J; Muir M; Klinowska T; Brunton VG
    Breast Cancer Res Treat; 2020 Feb; 179(3):543-555. PubMed ID: 31705351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: ALTERNATIVE.
    Johnston SRD; Hegg R; Im SA; Park IH; Burdaeva O; Kurteva G; Press MF; Tjulandin S; Iwata H; Simon SD; Kenny S; Sarp S; Izquierdo MA; Williams LS; Gradishar WJ
    J Clin Oncol; 2018 Mar; 36(8):741-748. PubMed ID: 29244528
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer.
    Franco YL; Ramakrishnan V; Vaidya TR; Mody H; Perez L; Ait-Oudhia S
    J Pharmacokinet Pharmacodyn; 2021 Apr; 48(2):273-293. PubMed ID: 33389550
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Construction of Nucleolin-Targeted Lipid Nanobubbles and Contrast-Enhanced Ultrasound Molecular Imaging in Triple-Negative Breast Cancer.
    Fang K; Wang L; Huang H; Lan M; Shen D; Dong S; Guo Y
    Pharm Res; 2020 Jul; 37(7):145. PubMed ID: 32666304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells.
    McDermott MSJ; Conlon N; Browne BC; Szabo A; Synnott NC; O'Brien NA; Duffy MJ; Crown J; O'Donovan N
    Cancers (Basel); 2019 Feb; 11(2):. PubMed ID: 30743996
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis.
    Fleeman N; Bagust A; Boland A; Dickson R; Dundar Y; Moonan M; Oyee J; Blundell M; Davis H; Armstrong A; Thorp N
    Health Technol Assess; 2011; 15(42):1-93, iii-iv. PubMed ID: 22152751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. miR-221 confers lapatinib resistance by negatively regulating p27
    Huynh TK; Huang CH; Chen JY; Yao JH; Yang YS; Wei YL; Chen HF; Chen CH; Tu CY; Hsu YM; Liu LC; Huang WC
    Cancer Sci; 2021 Oct; 112(10):4234-4245. PubMed ID: 34382727
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer.
    Alexander PB; Chen R; Gong C; Yuan L; Jasper JS; Ding Y; Markowitz GJ; Yang P; Xu X; McDonnell DP; Song E; Wang XF
    J Biol Chem; 2017 Jan; 292(2):748-759. PubMed ID: 27903634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of EnR stress by Melatonin enhances the cytotoxic effect of Lapatinib in HER2-positive breast cancer.
    Sang X; Li L; Rui C; Liu Y; Liu Z; Tao Z; Cheng H; Liu P
    Cancer Lett; 2021 Oct; 518():82-93. PubMed ID: 34153400
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.