152 related articles for article (PubMed ID: 37805163)
1. Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Zhou Y; Guo Y; Ran M; Shan W; Granchi C; Giovannetti E; Minutolo F; Peters GJ; Tam KY
Cancer Lett; 2023 Nov; 577():216425. PubMed ID: 37805163
[TBL] [Abstract][Full Text] [Related]
2. Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models.
Guo Y; Lu X; Zhou Y; Chen WH; Tam KY
Exp Cell Res; 2023 Dec; 433(2):113830. PubMed ID: 37913974
[TBL] [Abstract][Full Text] [Related]
3. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
[TBL] [Abstract][Full Text] [Related]
4. Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity.
Kwak CH; Jin L; Han JH; Han CW; Kim E; Cho M; Chung TW; Bae SJ; Jang SB; Ha KT
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825675
[TBL] [Abstract][Full Text] [Related]
5. PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway.
Pai S; Yadav VK; Kuo KT; Pikatan NW; Lin CS; Chien MH; Lee WH; Hsiao M; Chiu SC; Yeh CT; Tsai JT
Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768921
[No Abstract] [Full Text] [Related]
6. Blocking circ-CNST suppresses malignant behaviors of osteosarcoma cells and inhibits glycolysis through circ-CNST-miR-578-LDHA/PDK1 ceRNA networks.
Hu R; Chen S; Yan J
J Orthop Surg Res; 2021 May; 16(1):300. PubMed ID: 33962616
[TBL] [Abstract][Full Text] [Related]
7. Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression.
Yang ES; Do Y; Cheon SY; Kim B; Ling J; Cho MK; Kim T; Bae SJ; Ha KT
Oncol Rep; 2023 Apr; 49(4):. PubMed ID: 36825595
[TBL] [Abstract][Full Text] [Related]
8. Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and reactive oxygen species production.
Newington JT; Rappon T; Albers S; Wong DY; Rylett RJ; Cumming RC
J Biol Chem; 2012 Oct; 287(44):37245-58. PubMed ID: 22948140
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer.
Yang Z; Zhang SL; Hu X; Tam KY
Eur J Pharmacol; 2018 Nov; 838():41-52. PubMed ID: 30213498
[TBL] [Abstract][Full Text] [Related]
10. Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models.
Guo Y; Zhou Y; Wu P; Ran M; Xu N; Shan W; Sha O; Tam KY
Chem Biol Interact; 2023 Jun; 378():110467. PubMed ID: 37004952
[TBL] [Abstract][Full Text] [Related]
11. Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway.
Sun Y; Chen Y; Xu M; Liu C; Shang H; Wang C
Biomed Res Int; 2020; 2020():9243681. PubMed ID: 32685545
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells.
Zhang W; Wang C; Hu X; Lian Y; Ding C; Ming L
Oncol Rep; 2022 Apr; 47(4):. PubMed ID: 35191522
[TBL] [Abstract][Full Text] [Related]
13. Targeting the monocarboxylate transporter MCT2 and lactate dehydrogenase A LDHA in cancer cells with FX-11 and AR-C155858 inhibitors.
Alobaidi B; Hashimi SM; Alqosaibi AI; AlQurashi N; Alhazmi S
Eur Rev Med Pharmacol Sci; 2023 Jul; 27(14):6605-6617. PubMed ID: 37522672
[TBL] [Abstract][Full Text] [Related]
14. A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells.
Kawano Y; Sasano T; Arima Y; Kushima S; Tsujita K; Matsuoka M; Hata H
Biochem Biophys Res Commun; 2022 Jan; 587():153-159. PubMed ID: 34875534
[TBL] [Abstract][Full Text] [Related]
15. LncRNA FAM83A-AS1 facilitates tumor proliferation and the migration via the HIF-1α/ glycolysis axis in lung adenocarcinoma.
Chen Z; Hu Z; Sui Q; Huang Y; Zhao M; Li M; Liang J; Lu T; Zhan C; Lin Z; Sun F; Wang Q; Tan L
Int J Biol Sci; 2022; 18(2):522-535. PubMed ID: 35002507
[No Abstract] [Full Text] [Related]
16. Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.
Anwar S; Shamsi A; Mohammad T; Islam A; Hassan MI
Biochim Biophys Acta Rev Cancer; 2021 Aug; 1876(1):188568. PubMed ID: 34023419
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of pyruvate dehydrogenase kinase‑1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming.
Xu H; He Y; Ma J; Zhao Y; Liu Y; Sun L; Su J
Int J Oncol; 2020 Sep; 57(3):733-742. PubMed ID: 32705170
[TBL] [Abstract][Full Text] [Related]
18. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
Zhu S; Chen W; Wang J; Qi L; Pan H; Feng Z; Tian D
Theranostics; 2021; 11(7):3359-3375. PubMed ID: 33537092
[No Abstract] [Full Text] [Related]
19. SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.
Xu L; Li Y; Zhou L; Dorfman RG; Liu L; Cai R; Jiang C; Tang D; Wang Y; Zou X; Wang L; Zhang M
Cancer Med; 2019 May; 8(5):2380-2391. PubMed ID: 30993888
[TBL] [Abstract][Full Text] [Related]
20. Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation.
Xiang S; Huang D; He Q; Li J; Tam KY; Zhang SL; He Y
Eur J Med Chem; 2020 Oct; 203():112579. PubMed ID: 32688200
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]