These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 37824365)

  • 1. Activation/Deactivation Free-Energy Profiles for the β
    Calderón JC; Ibrahim P; Gobbo D; Gervasio FL; Clark T
    J Chem Inf Model; 2023 Oct; 63(20):6332-6343. PubMed ID: 37824365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation.
    Bhattacharya S; Hall SE; Li H; Vaidehi N
    Biophys J; 2008 Mar; 94(6):2027-42. PubMed ID: 18065472
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Understanding the effects on constitutive activation and drug binding of a D130N mutation in the β2 adrenergic receptor via molecular dynamics simulation.
    Zhu Y; Yuan Y; Xiao X; Zhang L; Guo Y; Pu X
    J Mol Model; 2014 Nov; 20(11):2491. PubMed ID: 25342155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations.
    Seifert R; Wenzel-Seifert K; Gether U; Kobilka BK
    J Pharmacol Exp Ther; 2001 Jun; 297(3):1218-26. PubMed ID: 11356949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor.
    Chen Y; Fleetwood O; Pérez-Conesa S; Delemotte L
    J Chem Inf Model; 2021 Dec; 61(12):6024-6037. PubMed ID: 34780174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.
    Katritch V; Reynolds KA; Cherezov V; Hanson MA; Roth CB; Yeager M; Abagyan R
    J Mol Recognit; 2009; 22(4):307-18. PubMed ID: 19353579
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists.
    Swaminath G; Deupi X; Lee TW; Zhu W; Thian FS; Kobilka TS; Kobilka B
    J Biol Chem; 2005 Jun; 280(23):22165-71. PubMed ID: 15817484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of Drug Efficacy Guided by Free Energy Simulations of the β
    Panel N; Vo DD; Kahlous NA; Hübner H; Tiedt S; Matricon P; Pacalon J; Fleetwood O; Kampen S; Luttens A; Delemotte L; Kihlberg J; Gmeiner P; Carlsson J
    Angew Chem Int Ed Engl; 2023 May; 62(22):e202218959. PubMed ID: 36914577
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sustained activation of a G protein-coupled receptor via "anchored" agonist binding. Molecular localization of the salmeterol exosite within the 2-adrenergic receptor.
    Green SA; Spasoff AP; Coleman RA; Johnson M; Liggett SB
    J Biol Chem; 1996 Sep; 271(39):24029-35. PubMed ID: 8798639
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational mapping of the conformational transitions in agonist selective pathways of a G-protein coupled receptor.
    Bhattacharya S; Vaidehi N
    J Am Chem Soc; 2010 Apr; 132(14):5205-14. PubMed ID: 20235532
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Determinants of Neutral Antagonism and Inverse Agonism in the β
    Calderón JC; Ibrahim P; Gobbo D; Gervasio FL; Clark T
    J Chem Inf Model; 2024 Mar; 64(6):2045-2057. PubMed ID: 38447156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane-Facilitated Receptor Access and Binding Mechanisms of Long-Acting
    Szlenk CT; Gc JB; Natesan S
    Mol Pharmacol; 2021 Oct; 100(4):406-427. PubMed ID: 34334369
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GDP Release from the Open Conformation of Gα Requires Allosteric Signaling from the Agonist-Bound Human β
    Kumar V; Hoag H; Sader S; Scorese N; Liu H; Wu C
    J Chem Inf Model; 2020 Aug; 60(8):4064-4075. PubMed ID: 32786510
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DIRECT-ID: An automated method to identify and quantify conformational variations--application to β2 -adrenergic GPCR.
    Lakkaraju SK; Lemkul JA; Huang J; MacKerell AD
    J Comput Chem; 2016 Feb; 37(4):416-25. PubMed ID: 26558323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An insilico approach to high altitude pulmonary edema - Molecular modeling of human beta2 adrenergic receptor and its interaction with Salmeterol & Nifedipine.
    Chandramoorthi GD; Piramanayagam S; Marimuthu P
    J Mol Model; 2008 Sep; 14(9):849-56. PubMed ID: 18512086
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
    Goetz A; Lanig H; Gmeiner P; Clark T
    J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling.
    Fleetwood O; Carlsson J; Delemotte L
    Elife; 2021 Jan; 10():. PubMed ID: 33506760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.
    Tikhonova IG; Selvam B; Ivetac A; Wereszczynski J; McCammon JA
    Biochemistry; 2013 Aug; 52(33):5593-603. PubMed ID: 23879802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. General Metadynamics Protocol To Simulate Activation/Deactivation of Class A GPCRs: Proof of Principle for the Serotonin Receptor.
    Calderón JC; Ibrahim P; Gobbo D; Gervasio FL; Clark T
    J Chem Inf Model; 2023 May; 63(10):3105-3117. PubMed ID: 37161278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor.
    Ghanouni P; Gryczynski Z; Steenhuis JJ; Lee TW; Farrens DL; Lakowicz JR; Kobilka BK
    J Biol Chem; 2001 Jul; 276(27):24433-6. PubMed ID: 11320077
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.