BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 37830570)

  • 1. Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant Smoothened and GLI into Glioma Primary Cilia.
    Shi P; Tian J; Mallinger JC; Ling D; Deleyrolle LP; McIntyre JC; Caspary T; Breunig JJ; Sarkisian MR
    Cells; 2023 Sep; 12(19):. PubMed ID: 37830570
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.
    Larkins CE; Aviles GD; East MP; Kahn RA; Caspary T
    Mol Biol Cell; 2011 Dec; 22(23):4694-703. PubMed ID: 21976698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.
    Nozaki S; Katoh Y; Terada M; Michisaka S; Funabashi T; Takahashi S; Kontani K; Nakayama K
    J Cell Sci; 2017 Feb; 130(3):563-576. PubMed ID: 27927754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
    Bay SN; Long AB; Caspary T
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1570-1575. PubMed ID: 29378965
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TULP3 is required for localization of membrane-associated proteins ARL13B and INPP5E to primary cilia.
    Han S; Miyoshi K; Shikada S; Amano G; Wang Y; Yoshimura T; Katayama T
    Biochem Biophys Res Commun; 2019 Jan; 509(1):227-234. PubMed ID: 30583862
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
    Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
    PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
    Fujisawa S; Qiu H; Nozaki S; Chiba S; Katoh Y; Nakayama K
    Biol Open; 2021 Sep; 10(9):. PubMed ID: 34447983
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
    Schembs L; Willems A; Hasenpusch-Theil K; Cooper JD; Whiting K; Burr K; Bøstrand SMK; Selvaraj BT; Chandran S; Theil T
    Cell Rep; 2022 May; 39(7):110811. PubMed ID: 35584663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.
    Arensdorf AM; Dillard ME; Menke JM; Frank MW; Rock CO; Ogden SK
    Cell Rep; 2017 Jun; 19(10):2074-2087. PubMed ID: 28591579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
    Chong YC; Mann RK; Zhao C; Kato M; Beachy PA
    Genes Dev; 2015 Feb; 29(3):262-76. PubMed ID: 25644602
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance.
    Ferent J; Constable S; Gigante ED; Yam PT; Mariani LE; Legué E; Liem KF; Caspary T; Charron F
    Cell Rep; 2019 Dec; 29(11):3356-3366.e3. PubMed ID: 31825820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.
    Qin J; Lin Y; Norman RX; Ko HW; Eggenschwiler JT
    Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1456-61. PubMed ID: 21209331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.
    Kim J; Kato M; Beachy PA
    Proc Natl Acad Sci U S A; 2009 Dec; 106(51):21666-71. PubMed ID: 19996169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
    Barakat B; Yu L; Lo C; Vu D; De Luca E; Cain JE; Martelotto LG; Dedhar S; Sadler AJ; Wang D; Watkins DN; Hannigan GE
    EMBO Rep; 2013 Sep; 14(9):837-44. PubMed ID: 23877428
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis.
    Yang S; Wang C
    Bone; 2012 Sep; 51(3):407-17. PubMed ID: 22771375
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms.
    Rosengren T; Larsen LJ; Pedersen LB; Christensen ST; Møller LB
    Cell Mol Life Sci; 2018 Jul; 75(14):2663-2680. PubMed ID: 29396625
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bi-allelic Variations of SMO in Humans Cause a Broad Spectrum of Developmental Anomalies Due to Abnormal Hedgehog Signaling.
    Le TL; Sribudiani Y; Dong X; Huber C; Kois C; Baujat G; Gordon CT; Mayne V; Galmiche L; Serre V; Goudin N; Zarhrate M; Bole-Feysot C; Masson C; Nitschké P; Verheijen FW; Pais L; Pelet A; Sadedin S; Pugh JA; Shur N; White SM; El Chehadeh S; Christodoulou J; Cormier-Daire V; Hofstra RMW; Lyonnet S; Tan TY; Attié-Bitach T; Kerstjens-Frederikse WS; Amiel J; Thomas S
    Am J Hum Genet; 2020 Jun; 106(6):779-792. PubMed ID: 32413283
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ERICH3 in Primary Cilia Regulates Cilium Formation and the Localisations of Ciliary Transport and Sonic Hedgehog Signaling Proteins.
    Alsolami M; Kuhns S; Alsulami M; Blacque OE
    Sci Rep; 2019 Nov; 9(1):16519. PubMed ID: 31712586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry.
    Qiu H; Fujisawa S; Nozaki S; Katoh Y; Nakayama K
    Biol Open; 2021 Jan; 10(1):. PubMed ID: 33372066
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.