BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 37831762)

  • 1. Molecular basis of ClC-6 function and its impairment in human disease.
    Zhang B; Zhang S; Polovitskaya MM; Yi J; Ye B; Li R; Huang X; Yin J; Neuens S; Balfroid T; Soblet J; Vens D; Aeby A; Li X; Cai J; Song Y; Li Y; Tartaglia M; Li Y; Jentsch TJ; Yang M; Liu Z
    Sci Adv; 2023 Oct; 9(41):eadg4479. PubMed ID: 37831762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Recurrent Gain-of-Function Mutation in CLCN6, Encoding the ClC-6 Cl
    Polovitskaya MM; Barbini C; Martinelli D; Harms FL; Cole FS; Calligari P; Bocchinfuso G; Stella L; Ciolfi A; Niceta M; Rizza T; Shinawi M; Sisco K; Johannsen J; Denecke J; Carrozzo R; Wegner DJ; Kutsche K; Tartaglia M; Jentsch TJ
    Am J Hum Genet; 2020 Dec; 107(6):1062-1077. PubMed ID: 33217309
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered voltage-dependence of slowly activating chloride-proton antiport by late endosomal ClC-6 explains distinct neurological disorders.
    Zifarelli G; Pusch M; Fong P
    J Physiol; 2022 May; 600(9):2147-2164. PubMed ID: 35262198
    [TBL] [Abstract][Full Text] [Related]  

  • 4. West Syndrome Caused By a Chloride/Proton Exchange-Uncoupling CLCN6 Mutation Related to Autophagic-Lysosomal Dysfunction.
    He H; Cao X; Yin F; Wu T; Stauber T; Peng J
    Mol Neurobiol; 2021 Jun; 58(6):2990-2999. PubMed ID: 33590434
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl-/1H+ exchanger ClC-7/Ostm1.
    Ludwig CF; Ullrich F; Leisle L; Stauber T; Jentsch TJ
    J Biol Chem; 2013 Oct; 288(40):28611-9. PubMed ID: 23983121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease.
    Jentsch TJ; Pusch M
    Physiol Rev; 2018 Jul; 98(3):1493-1590. PubMed ID: 29845874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.
    Leisle L; Ludwig CF; Wagner FA; Jentsch TJ; Stauber T
    EMBO J; 2011 Jun; 30(11):2140-52. PubMed ID: 21527911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutamate 268 regulates transport probability of the anion/proton exchanger ClC-5.
    Grieschat M; Alekov AK
    J Biol Chem; 2012 Mar; 287(11):8101-9. PubMed ID: 22267722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular mechanisms of ion conduction in ClC-type chloride channels: lessons from disease-causing mutations.
    Fahlke C
    Kidney Int; 2000 Mar; 57(3):780-6. PubMed ID: 10720929
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1.
    Schrecker M; Korobenko J; Hite RK
    Elife; 2020 Aug; 9():. PubMed ID: 32749217
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Secondary water pore formation for proton transport in a ClC exchanger revealed by an atomistic molecular-dynamics simulation.
    Ko YJ; Jo WH
    Biophys J; 2010 May; 98(10):2163-9. PubMed ID: 20483324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of Dent's disease mutations of CLC-5 reveals a correlation between functional and cell biological consequences and protein structure.
    Smith AJ; Reed AA; Loh NY; Thakker RV; Lippiat JD
    Am J Physiol Renal Physiol; 2009 Feb; 296(2):F390-7. PubMed ID: 19019917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Electro-steric opening of the CLC-2 chloride channel gate.
    De Jesús-Pérez JJ; Méndez-Maldonado GA; López-Romero AE; Esparza-Jasso D; González-Hernández IL; De la Rosa V; Gastélum-Garibaldi R; Sánchez-Rodríguez JE; Arreola J
    Sci Rep; 2021 Jun; 11(1):13127. PubMed ID: 34162897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of ClC-2 gating by intracellular ATP.
    Stölting G; Teodorescu G; Begemann B; Schubert J; Nabbout R; Toliat MR; Sander T; Nürnberg P; Lerche H; Fahlke C
    Pflugers Arch; 2013 Oct; 465(10):1423-37. PubMed ID: 23632988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
    Weinert S; Gimber N; Deuschel D; Stuhlmann T; Puchkov D; Farsi Z; Ludwig CF; Novarino G; López-Cayuqueo KI; Planells-Cases R; Jentsch TJ
    EMBO J; 2020 May; 39(9):e103358. PubMed ID: 32118314
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins.
    Scheel O; Zdebik AA; Lourdel S; Jentsch TJ
    Nature; 2005 Jul; 436(7049):424-7. PubMed ID: 16034422
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ClC-5: Physiological role and biophysical mechanisms.
    Pusch M; Zifarelli G
    Cell Calcium; 2015 Jul; 58(1):57-66. PubMed ID: 25443653
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proton block of the CLC-5 Cl-/H+ exchanger.
    Picollo A; Malvezzi M; Accardi A
    J Gen Physiol; 2010 Jun; 135(6):653-9. PubMed ID: 20513761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation.
    Imbrici P; Maggi L; Mangiatordi GF; Dinardo MM; Altamura C; Brugnoni R; Alberga D; Pinter GL; Ricci G; Siciliano G; Micheli R; Annicchiarico G; Lattanzi G; Nicolotti O; Morandi L; Bernasconi P; Desaphy JF; Mantegazza R; Camerino DC
    J Physiol; 2015 Sep; 593(18):4181-99. PubMed ID: 26096614
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker.
    Dave S; Sheehan JH; Meiler J; Strange K
    Channels (Austin); 2010; 4(4):289-301. PubMed ID: 20581474
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.