These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models. von Achenbach C; Weller M; Kaulich K; Gramatzki D; Zacher A; Fabbro D; Reifenberger G; Szabó E J Neurochem; 2020 May; 153(4):510-524. PubMed ID: 31618458 [TBL] [Abstract][Full Text] [Related]
3. Crosstalk between PI3K/AKT/mTOR and WNT/β-Catenin signaling in GBM - Could combination therapy checkmate the collusion? Daisy Precilla S; Biswas I; Kuduvalli SS; Anitha TS Cell Signal; 2022 Jul; 95():110350. PubMed ID: 35525406 [TBL] [Abstract][Full Text] [Related]
4. Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding. Sami A; Karsy M Tumour Biol; 2013 Aug; 34(4):1991-2002. PubMed ID: 23625692 [TBL] [Abstract][Full Text] [Related]
5. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Park S; Zhao D; Hatanpaa KJ; Mickey BE; Saha D; Boothman DA; Story MD; Wong ET; Burma S; Georgescu MM; Rangnekar VM; Chauncey SS; Habib AA Cancer Res; 2009 May; 69(10):4107-11. PubMed ID: 19435890 [TBL] [Abstract][Full Text] [Related]
6. PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer. Marquard FE; Jücker M Biochem Pharmacol; 2020 Feb; 172():113729. PubMed ID: 31785230 [TBL] [Abstract][Full Text] [Related]
7. Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma. Jhanwar-Uniyal M; Dominguez JF; Mohan AL; Tobias ME; Gandhi CD Adv Biol Regul; 2022 Jan; 83():100854. PubMed ID: 34996736 [TBL] [Abstract][Full Text] [Related]
8. Hypoxia enhances the migration and invasion of human glioblastoma U87 cells through PI3K/Akt/mTOR/HIF-1α pathway. Huang W; Ding X; Ye H; Wang J; Shao J; Huang T Neuroreport; 2018 Dec; 29(18):1578-1585. PubMed ID: 30371540 [TBL] [Abstract][Full Text] [Related]
9. Inhibiting 4EBP1 in Glioblastoma. Fan QW; Nicolaides TP; Weiss WA Clin Cancer Res; 2018 Jan; 24(1):14-21. PubMed ID: 28696243 [TBL] [Abstract][Full Text] [Related]
10. RES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes. Weinberg MA Anticancer Drugs; 2016 Jul; 27(6):475-87. PubMed ID: 26918392 [TBL] [Abstract][Full Text] [Related]
11. Voxtalisib and low intensity pulsed ultrasound combinatorial effect on glioblastoma multiforme cancer stem cells via PI3K/AKT/mTOR. Tutak I; Ozdil B; Uysal A Pathol Res Pract; 2022 Nov; 239():154145. PubMed ID: 36240647 [TBL] [Abstract][Full Text] [Related]
12. Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma. Barzegar Behrooz A; Talaie Z; Jusheghani F; Łos MJ; Klonisch T; Ghavami S Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163279 [TBL] [Abstract][Full Text] [Related]
13. Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer. Yu L; Wei J; Liu P Semin Cancer Biol; 2022 Oct; 85():69-94. PubMed ID: 34175443 [TBL] [Abstract][Full Text] [Related]
15. Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway. Burris HA Cancer Chemother Pharmacol; 2013 Apr; 71(4):829-42. PubMed ID: 23377372 [TBL] [Abstract][Full Text] [Related]
16. Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer. Moench R; Grimmig T; Kannen V; Tripathi S; Faber M; Moll EM; Chandraker A; Lissner R; Germer CT; Waaga-Gasser AM; Gasser M Oncotarget; 2016 Oct; 7(42):68749-68767. PubMed ID: 27626684 [TBL] [Abstract][Full Text] [Related]
17. The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer. Slomovitz BM; Coleman RL Clin Cancer Res; 2012 Nov; 18(21):5856-64. PubMed ID: 23082003 [TBL] [Abstract][Full Text] [Related]
18. PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma. Li X; Wu C; Chen N; Gu H; Yen A; Cao L; Wang E; Wang L Oncotarget; 2016 May; 7(22):33440-50. PubMed ID: 26967052 [TBL] [Abstract][Full Text] [Related]
19. Defining the role of mTOR pathway in the regulation of stem cells of glioblastoma. Jhanwar-Uniyal M; Gellerson O; Bree J; Das M; Kleinman G; Gandhi CD Adv Biol Regul; 2023 May; 88():100946. PubMed ID: 36658088 [TBL] [Abstract][Full Text] [Related]
20. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]