These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 37849894)

  • 1. Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis.
    Fang M; Deibler SK; Nana AL; Vatsavayai SC; Banday S; Zhou Y; Almeida S; Weiss A; Brown RH; Seeley WW; Gao FB; Green MR
    Front Neurosci; 2023; 17():1251228. PubMed ID: 37849894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.
    Zhang Z; Almeida S; Lu Y; Nishimura AL; Peng L; Sun D; Wu B; Karydas AM; Tartaglia MC; Fong JC; Miller BL; Farese RV; Moore MJ; Shaw CE; Gao FB
    PLoS One; 2013; 8(10):e76055. PubMed ID: 24143176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis.
    Mitra J; Hegde ML
    J Exp Neurosci; 2019; 13():1179069519880166. PubMed ID: 31656396
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
    Mitra J; Guerrero EN; Hegde PM; Liachko NF; Wang H; Vasquez V; Gao J; Pandey A; Taylor JP; Kraemer BC; Wu P; Boldogh I; Garruto RM; Mitra S; Rao KS; Hegde ML
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4696-4705. PubMed ID: 30770445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43.
    Donde A; Sun M; Jeong YH; Wen X; Ling J; Lin S; Braunstein K; Nie S; Wang S; Chen L; Wong PC
    Autophagy; 2020 Apr; 16(4):672-682. PubMed ID: 31242080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanisms linking loss of TDP-43 function to amyotrophic lateral sclerosis/frontotemporal dementia-related genes.
    Koike Y
    Neurosci Res; 2024 Nov; 208():1-7. PubMed ID: 38723906
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
    Guerrero EN; Mitra J; Wang H; Rangaswamy S; Hegde PM; Basu P; Rao KS; Hegde ML
    Hum Mol Genet; 2019 Aug; 28(15):2459-2476. PubMed ID: 31067307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.
    Lépine S; Nauleau-Javaudin A; Deneault E; Chen CX; Abdian N; Franco-Flores AK; Haghi G; Castellanos-Montiel MJ; Maussion G; Chaineau M; Durcan TM
    iScience; 2024 Mar; 27(3):109166. PubMed ID: 38433895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
    Konopka A; Whelan DR; Jamali MS; Perri E; Shahheydari H; Toth RP; Parakh S; Robinson T; Cheong A; Mehta P; Vidal M; Ragagnin AMG; Khizhnyak I; Jagaraj CJ; Galper J; Grima N; Deva A; Shadfar S; Nicholson GA; Yang S; Cutts SM; Horejsi Z; Bell TDM; Walker AK; Blair IP; Atkin JD
    Mol Neurodegener; 2020 Sep; 15(1):51. PubMed ID: 32907630
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid in vitro quantification of TDP-43 and FUS mislocalisation for screening of gene variants implicated in frontotemporal dementia and amyotrophic lateral sclerosis.
    Oyston LJ; Ubiparipovic S; Fitzpatrick L; Hallupp M; Boccanfuso LM; Kwok JB; Dobson-Stone C
    Sci Rep; 2021 Jul; 11(1):14881. PubMed ID: 34290285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice.
    McCann EP; Fifita JA; Grima N; Galper J; Mehta P; Freckleton SE; Zhang KY; Henden L; Hogan AL; Chan Moi Fat S; Wu SS; Jagaraj CJ; Berning BA; Williams KL; Twine NA; Bauer D; Piguet O; Hodges J; Kwok JBJ; Halliday GM; Kiernan MC; Atkin J; Rowe DB; Nicholson GA; Walker AK; Blair IP; Yang S
    J Neurol Neurosurg Psychiatry; 2020 Feb; 91(2):162-171. PubMed ID: 31690696
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TDP-43 is a ubiquitylation substrate of the SCF
    Rayner SL; Yang S; Farrawell NE; Jagaraj CJ; Cheng F; Davidson JM; Luu L; Redondo AG; Rábano A; Borrego-Hernández D; Atkin JD; Morsch M; Blair IP; Yerbury JJ; Chung R; Lee A
    Neurobiol Dis; 2022 Jun; 167():105673. PubMed ID: 35231559
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons.
    Ratti A; Gumina V; Lenzi P; Bossolasco P; Fulceri F; Volpe C; Bardelli D; Pregnolato F; Maraschi A; Fornai F; Silani V; Colombrita C
    Neurobiol Dis; 2020 Nov; 145():105051. PubMed ID: 32827688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
    Fazal R; Boeynaems S; Swijsen A; De Decker M; Fumagalli L; Moisse M; Vanneste J; Guo W; Boon R; Vercruysse T; Eggermont K; Swinnen B; Beckers J; Pakravan D; Vandoorne T; Vanden Berghe P; Verfaillie C; Van Den Bosch L; Van Damme P
    EMBO J; 2021 Apr; 40(7):e106177. PubMed ID: 33694180
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
    Montalbano M; McAllen S; Cascio FL; Sengupta U; Garcia S; Bhatt N; Ellsworth A; Heidelman EA; Johnson OD; Doskocil S; Kayed R
    Neurobiol Dis; 2020 Dec; 146():105130. PubMed ID: 33065281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
    Afroz T; Chevalier E; Audrain M; Dumayne C; Ziehm T; Moser R; Egesipe AL; Mottier L; Ratnam M; Neumann M; Havas D; Ollier R; Piorkowska K; Chauhan M; Silva AB; Thapa S; Stöhr J; Bavdek A; Eligert V; Adolfsson O; Nelson PT; Porta S; Lee VM; Pfeifer A; Kosco-Vilbois M; Seredenina T
    Neurobiol Dis; 2023 Apr; 179():106050. PubMed ID: 36809847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A panel of TDP-43-regulated splicing events verifies loss of TDP-43 function in amyotrophic lateral sclerosis brain tissue.
    Cao MC; Ryan B; Wu J; Curtis MA; Faull RLM; Dragunow M; Scotter EL
    Neurobiol Dis; 2023 Sep; 185():106245. PubMed ID: 37527763
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spinal cord extracts of amyotrophic lateral sclerosis spread TDP-43 pathology in cerebral organoids.
    Tamaki Y; Ross JP; Alipour P; Castonguay CÉ; Li B; Catoire H; Rochefort D; Urushitani M; Takahashi R; Sonnen JA; Stifani S; Dion PA; Rouleau GA
    PLoS Genet; 2023 Feb; 19(2):e1010606. PubMed ID: 36745687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
    Chou CC; Zhang Y; Umoh ME; Vaughan SW; Lorenzini I; Liu F; Sayegh M; Donlin-Asp PG; Chen YH; Duong DM; Seyfried NT; Powers MA; Kukar T; Hales CM; Gearing M; Cairns NJ; Boylan KB; Dickson DW; Rademakers R; Zhang YJ; Petrucelli L; Sattler R; Zarnescu DC; Glass JD; Rossoll W
    Nat Neurosci; 2018 Feb; 21(2):228-239. PubMed ID: 29311743
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
    Fang MY; Markmiller S; Vu AQ; Javaherian A; Dowdle WE; Jolivet P; Bushway PJ; Castello NA; Baral A; Chan MY; Linsley JW; Linsley D; Mercola M; Finkbeiner S; Lecuyer E; Lewcock JW; Yeo GW
    Neuron; 2019 Sep; 103(5):802-819.e11. PubMed ID: 31272829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.