BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 37851084)

  • 1. Effects of gene polymorphisms on delayed MTX clearance, toxicity, and metabolomic changes after HD-MTX treatment in children with acute lymphoblastic leukemia.
    Zhou Y; He H; Ding L; Wang T; Liu X; Zhang M; Zhang A; Fu J
    Eur J Pediatr; 2024 Feb; 183(2):581-590. PubMed ID: 37851084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.
    Haase R; Elsner K; Merkel N; Stiefel M; Mauz-Körholz C; Kramm CM; Körholz D
    Klin Padiatr; 2012 Apr; 224(3):156-9. PubMed ID: 22513795
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polymorphisms of SLC19A1 80 G>A, MTHFR 677 C>T, and Tandem TS Repeats Influence Pharmacokinetics, Acute Liver Toxicity, and Vomiting in Children With Acute Lymphoblastic Leukemia Treated With High Doses of Methotrexate.
    Cwiklinska M; Czogala M; Kwiecinska K; Madetko-Talowska A; Szafarz M; Pawinska K; Wieczorek A; Klekawka T; Rej M; Stepien K; Halubiec P; Lazarczyk A; Miklusiak K; Bik-Multanowski M; Balwierz W; Skoczen S
    Front Pediatr; 2020; 8():307. PubMed ID: 32612964
    [No Abstract]   [Full Text] [Related]  

  • 4. Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
    Faganel Kotnik B; Grabnar I; Bohanec Grabar P; Dolžan V; Jazbec J
    Eur J Clin Pharmacol; 2011 Oct; 67(10):993-1006. PubMed ID: 21509569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relationship between methylenetetrahydrofolate reductase gene polymorphisms and methotrexate drug metabolism and toxicity.
    Tan Y; Kong Q; Li X; Tang Y; Mai H; Zhen Z; Zhou D; Chen H
    Transl Pediatr; 2023 Jan; 12(1):31-45. PubMed ID: 36798930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia.
    Erčulj N; Kotnik BF; Debeljak M; Jazbec J; Dolžan V
    Leuk Lymphoma; 2012 Jun; 53(6):1096-104. PubMed ID: 22074251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of Folate-Related Gene Polymorphisms on High-Dose Methotrexate-Related Toxicity and Prognosis in Turkish Children with Acute Lymphoblastic Leukemia.
    Yazıcıoğlu B; Kaya Z; Güntekin Ergun S; Perçin F; Koçak Ü; Yenicesu İ; Gürsel T
    Turk J Haematol; 2017 Jun; 34(2):143-150. PubMed ID: 27094381
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High dose methotrexate in adult Egyptian patients with hematological malignancies: impact of ABCB1 3435C > T rs1045642 and MTHFR 677C > T rs1801133 polymorphisms on toxicities and delayed elimination.
    Ebid AIM; Hossam A; El Gammal MM; Soror S; Mangoud NOM; Mahmoud MA
    J Chemother; 2022 Oct; 34(6):381-390. PubMed ID: 34895107
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The influence of MTHFR genetic polymorphisms on methotrexate therapy in pediatric acute lymphoblastic leukemia.
    Shen Y; Wang Z; Zhou F; Jin R
    Open Life Sci; 2021; 16(1):1203-1212. PubMed ID: 34761111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional variants of gene encoding folate metabolizing enzyme and methotrexate-related toxicity in children with acute lymphoblastic leukemia.
    Kałużna E; Strauss E; Zając-Spychała O; Gowin E; Świątek-Kościelna B; Nowak J; Fichna M; Mańkowski P; Januszkiewicz-Lewandowska D
    Eur J Pharmacol; 2015 Dec; 769():93-9. PubMed ID: 26528799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer.
    Hagleitner MM; Coenen MJ; Aplenc R; Patiño-Garcia A; Chiusolo P; Gemmati D; De Mattei M; Ongaro A; Krajinovic M; Hoogerbrugge PM; Vermeulen SH; te Loo DM
    Pharmacogenomics J; 2014 Apr; 14(2):115-9. PubMed ID: 23648444
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia.
    Zgheib NK; Akra-Ismail M; Aridi C; Mahfouz R; Abboud MR; Solh H; Muwakkit SA
    Pharmacogenet Genomics; 2014 Aug; 24(8):387-96. PubMed ID: 25007187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of
    Karschnia P; Kurz SC; Brastianos PK; Winter SF; Gordon A; Jones S; Pisapia M; Nayyar N; Tonn JC; Batchelor TT; Plotkin SR; Dietrich J
    Neurology; 2023 Oct; 101(17):e1741-e1746. PubMed ID: 37527941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methotrexate elimination and toxicity: MTHFR 677C>T polymorphism in patients with primary CNS lymphoma treated with high-dose methotrexate.
    Choi YJ; Park H; Lee JS; Lee JY; Kim S; Kim TW; Park JS; Kim JE; Yoon DH; Suh C
    Hematol Oncol; 2017 Dec; 35(4):504-509. PubMed ID: 27781293
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gene polymorphisms in the folate metabolic pathway and risk of pediatric acute lymphoblastic leukemia: a case-control study in a Chinese population.
    Lv H; Hu SY; Du ZZ; Zhai Z; Cao L; Sun YN; Lu J; Li J; He HL; Chai YH; Wang Y
    Int J Clin Exp Pathol; 2018; 11(3):1724-1731. PubMed ID: 31938276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population.
    Lv S; Fan H; Li J; Yang H; Huang J; Shu X; Zhang L; Xu Y; Li X; Zuo J; Xiao C
    Front Pharmacol; 2018; 9():1390. PubMed ID: 30546311
    [No Abstract]   [Full Text] [Related]  

  • 17. Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR , TYMS, and TCII genes and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.
    Świerkot J; Ślęzak R; Karpiński P; Pawłowska J; Noga L; Szechiński J; Wiland P
    Pol Arch Med Wewn; 2015; 125(3):152-61. PubMed ID: 25599563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of Polymorphisms of ABCB1 and MTHFR on Methotrexate-Related Toxicities in Adults With Hematological Malignancies.
    Han J; Liu L; Meng L; Guo H; Zhang J; Han ZQ; Hong ZY
    Front Oncol; 2021; 11():759805. PubMed ID: 35004279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia.
    Wang SM; Sun LL; Zeng WX; Wu WS; Zhang GL
    Cancer Chemother Pharmacol; 2014 Aug; 74(2):283-9. PubMed ID: 24908438
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxic encephalopathy and delayed MTX clearance after high-dose methotrexate therapy in a child homozygous for the MTHFR C677T polymorphism.
    Müller J; Kralovánszky J; Adleff V; Pap E; Németh K; Komlósi V; Kovács G
    Anticancer Res; 2008; 28(5B):3051-4. PubMed ID: 19031955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.