BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 37862053)

  • 1. Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
    Gomez K; Allen HN; Duran P; Loya-Lopez S; Calderon-Rivera A; Moutal A; Tang C; Nelson TS; Perez-Miller S; Khanna R
    Pain; 2024 Apr; 165(4):866-883. PubMed ID: 37862053
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
    Dustrude ET; Wilson SM; Ju W; Xiao Y; Khanna R
    J Biol Chem; 2013 Aug; 288(34):24316-31. PubMed ID: 23836888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intranasal CRMP2-Ubc9 inhibitor regulates Na V 1.7 to alleviate trigeminal neuropathic pain.
    Loya-Lopez SI; Allen HN; Duran P; Calderon-Rivera A; Gomez K; Kumar U; Shields R; Zeng R; Dwivedi A; Saurabh S; Korczeniewska OA; Khanna R
    Pain; 2024 Mar; 165(3):573-588. PubMed ID: 37751532
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Non-SUMOylated CRMP2 decreases Na
    Gomez K; Ran D; Madura CL; Moutal A; Khanna R
    Mol Brain; 2021 Jan; 14(1):20. PubMed ID: 33478555
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain.
    François-Moutal L; Dustrude ET; Wang Y; Brustovetsky T; Dorame A; Ju W; Moutal A; Perez-Miller S; Brustovetsky N; Gokhale V; Khanna M; Khanna R
    Pain; 2018 Oct; 159(10):2115-2127. PubMed ID: 29847471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intranasal CRMP2-Ubc9 Inhibitor Regulates Na
    Loya-Lopez SI; Allen HN; Duran P; Calderon-Rivera A; Gomez K; Kumar U; Shields R; Zeng R; Dwivedi A; Saurabh S; Korczeniewska OA; Khanna R
    bioRxiv; 2023 Jul; ():. PubMed ID: 37502910
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
    Braden K; Stratton HJ; Salvemini D; Khanna R
    Neurobiol Pain; 2022; 11():100082. PubMed ID: 35024498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TNF-α mediated upregulation of Na
    de Macedo FHP; Aires RD; Fonseca EG; Ferreira RCM; Machado DPD; Chen L; Zhang FX; Souza IA; Lemos VS; Romero TRL; Moutal A; Khanna R; Zamponi GW; Cruz JS
    Mol Brain; 2019 Dec; 12(1):117. PubMed ID: 31888677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons.
    Ju W; Li Q; Wilson SM; Brittain JM; Meroueh L; Khanna R
    Channels (Austin); 2013; 7(3):153-9. PubMed ID: 23510938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conditional knockout of CRMP2 in neurons, but not astrocytes, disrupts spinal nociceptive neurotransmission to control the initiation and maintenance of chronic neuropathic pain.
    Boinon L; Yu J; Madura CL; Chefdeville A; Feinstein DL; Moutal A; Khanna R
    Pain; 2022 Feb; 163(2):e368-e381. PubMed ID: 35029600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific Nav1.7 regulation in the pathogenesis of chronic neuropathic pain.
    Moutal A; Cai S; Yu J; Stratton HJ; Chefdeville A; Gomez K; Ran D; Madura CL; Boinon L; Soto M; Zhou Y; Shan Z; Chew LA; Rodgers KE; Khanna R
    Pain; 2020 Nov; 161(11):2629-2651. PubMed ID: 32569093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Upregulation of interleukin-6 on Ca
    Liu Q; Chen W; Fan X; Wang J; Fu S; Cui S; Liao F; Cai J; Wang X; Huang Y; Su L; Zhong L; Yi M; Liu F; Wan Y
    Exp Neurol; 2019 Jul; 317():226-243. PubMed ID: 30872136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of hyperpolarization-activated, cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic pain.
    Wan Y
    Sheng Li Xue Bao; 2008 Oct; 60(5):579-80. PubMed ID: 18958363
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide.
    Moutal A; Yang X; Li W; Gilbraith KB; Luo S; Cai S; François-Moutal L; Chew LA; Yeon SK; Bellampalli SS; Qu C; Xie JY; Ibrahim MM; Khanna M; Park KD; Porreca F; Khanna R
    Pain; 2017 Dec; 158(12):2301-2319. PubMed ID: 28809766
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SENP1-Mediated deSUMOylation Regulates the Tumor Remodeling of Glioma Stem Cells Under Hypoxic Stress.
    Wen P; Li H; Liu L; Liu X; Xu Z; Dong J
    Technol Cancer Res Treat; 2024; 23():15330338241257490. PubMed ID: 38803001
    [No Abstract]   [Full Text] [Related]  

  • 16. Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.
    Moutal A; Wang Y; Yang X; Ji Y; Luo S; Dorame A; Bellampalli SS; Chew LA; Cai S; Dustrude ET; Keener JE; Marty MT; Vanderah TW; Khanna R
    Pain; 2017 Nov; 158(11):2203-2221. PubMed ID: 28767512
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain.
    Moutal A; Luo S; Largent-Milnes TM; Vanderah TW; Khanna R
    Neurobiol Pain; 2019; 5():. PubMed ID: 31080913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.
    Xie JY; Chew LA; Yang X; Wang Y; Qu C; Wang Y; Federici LM; Fitz SD; Ripsch MS; Due MR; Moutal A; Khanna M; White FA; Vanderah TW; Johnson PL; Porreca F; Khanna R
    Pain; 2016 Sep; 157(9):2124-2140. PubMed ID: 27537210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons.
    Loya-López SI; Duran P; Ran D; Calderon-Rivera A; Gomez K; Moutal A; Khanna R
    Neurobiol Pain; 2022; 12():100109. PubMed ID: 36531612
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.
    Zhang XF; Shieh CC; Chapman ML; Matulenko MA; Hakeem AH; Atkinson RN; Kort ME; Marron BE; Joshi S; Honore P; Faltynek CR; Krafte DS; Jarvis MF
    Neuropharmacology; 2010 Sep; 59(3):201-7. PubMed ID: 20566409
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.