These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 37865287)

  • 1. Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
    Broggini L; Barzago MM; Speranzini V; Schulte T; Sonzini F; Giono M; Romeo M; Milani P; Caminito S; Mazzini G; Rognoni P; Merlini G; Pappone C; Anastasia L; Nuvolone M; Palladini G; Diomede L; Ricagno S
    J Mol Biol; 2023 Dec; 435(24):168320. PubMed ID: 37865287
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cu(II) Binding Increases the Soluble Toxicity of Amyloidogenic Light Chains.
    Russo R; Romeo M; Schulte T; Maritan M; Oberti L; Barzago MM; Barbiroli A; Pappone C; Anastasia L; Palladini G; Diomede L; Ricagno S
    Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35055136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
    Swuec P; Lavatelli F; Tasaki M; Paissoni C; Rognoni P; Maritan M; Brambilla F; Milani P; Mauri P; Camilloni C; Palladini G; Merlini G; Ricagno S; Bolognesi M
    Nat Commun; 2019 Mar; 10(1):1269. PubMed ID: 30894521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils-A metric for predicting amyloid propensity.
    Martin EB; Williams A; Wooliver C; Heidel RE; Adams S; Dunlap J; Ramirez-Alvarado M; Blancas-Mejia LM; Lands RH; Kennel SJ; Wall JS
    PLoS One; 2017; 12(3):e0174152. PubMed ID: 28350808
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.
    Morgan GJ; Kelly JW
    J Mol Biol; 2016 Oct; 428(21):4280-4297. PubMed ID: 27569045
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains.
    Maritan M; Romeo M; Oberti L; Sormanni P; Tasaki M; Russo R; Ambrosetti A; Motta P; Rognoni P; Mazzini G; Barbiroli A; Palladini G; Vendruscolo M; Diomede L; Bolognesi M; Merlini G; Lavatelli F; Ricagno S
    J Mol Biol; 2020 Feb; 432(4):845-860. PubMed ID: 31874151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells.
    Imperlini E; Gnecchi M; Rognoni P; Sabidò E; Ciuffreda MC; Palladini G; Espadas G; Mancuso FM; Bozzola M; Malpasso G; Valentini V; Palladini G; Orrù S; Ferraro G; Milani P; Perlini S; Salvatore F; Merlini G; Lavatelli F
    Sci Rep; 2017 Nov; 7(1):15661. PubMed ID: 29142197
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Domain Interactions Determine the Amyloidogenicity of Antibody Light Chain Mutants.
    Weber B; Hora M; Kazman P; Pradhan T; Rührnößl F; Reif B; Buchner J
    J Mol Biol; 2020 Nov; 432(23):6187-6199. PubMed ID: 33058870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis.
    Lavatelli F; Imperlini E; Orrù S; Rognoni P; Sarnataro D; Palladini G; Malpasso G; Soriano ME; Di Fonzo A; Valentini V; Gnecchi M; Perlini S; Salvatore F; Merlini G
    FASEB J; 2015 Nov; 29(11):4614-28. PubMed ID: 26220173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.
    Guan J; Mishra S; Shi J; Plovie E; Qiu Y; Cao X; Gianni D; Jiang B; Del Monte F; Connors LH; Seldin DC; Lavatelli F; Rognoni P; Palladini G; Merlini G; Falk RH; Semigran MJ; Dec GW; Macrae CA; Liao R
    Basic Res Cardiol; 2013 Sep; 108(5):378. PubMed ID: 23982491
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A constant domain mutation in a patient-derived antibody light chain reveals principles of AL amyloidosis.
    Rottenaicher GJ; Absmeier RM; Meier L; Zacharias M; Buchner J
    Commun Biol; 2023 Feb; 6(1):209. PubMed ID: 36823438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular Mechanism of Pathogenesis and Treatment Strategies for AL Amyloidosis.
    Ikura H; Endo J; Kitakata H; Moriyama H; Sano M; Fukuda K
    Int J Mol Sci; 2022 Jun; 23(11):. PubMed ID: 35683015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
    Oberti L; Rognoni P; Barbiroli A; Lavatelli F; Russo R; Maritan M; Palladini G; Bolognesi M; Merlini G; Ricagno S
    Sci Rep; 2017 Dec; 7(1):16809. PubMed ID: 29196671
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis.
    Diomede L; Rognoni P; Lavatelli F; Romeo M; del Favero E; Cantù L; Ghibaudi E; di Fonzo A; Corbelli A; Fiordaliso F; Palladini G; Valentini V; Perfetti V; Salmona M; Merlini G
    Blood; 2014 Jun; 123(23):3543-52. PubMed ID: 24665135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains.
    O'Nuallain B; Allen A; Kennel SJ; Weiss DT; Solomon A; Wall JS
    Biochemistry; 2007 Feb; 46(5):1240-7. PubMed ID: 17260953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exploring the sequence features determining amyloidosis in human antibody light chains.
    Rawat P; Prabakaran R; Kumar S; Gromiha MM
    Sci Rep; 2021 Jul; 11(1):13785. PubMed ID: 34215782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
    Kazman P; Vielberg MT; Pulido Cendales MD; Hunziger L; Weber B; Hegenbart U; Zacharias M; Köhler R; Schönland S; Groll M; Buchner J
    Elife; 2020 Mar; 9():. PubMed ID: 32151314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation.
    Peterle D; Klimtchuk ES; Wales TE; Georgescauld F; Connors LH; Engen JR; Gursky O
    J Mol Biol; 2021 Dec; 433(24):167310. PubMed ID: 34678302
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of domain interactions in the aggregation of full-length immunoglobulin light chains.
    Rennella E; Morgan GJ; Kelly JW; Kay LE
    Proc Natl Acad Sci U S A; 2019 Jan; 116(3):854-863. PubMed ID: 30598439
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2A4 binds soluble and insoluble light chain aggregates from AL amyloidosis patients and promotes clearance of amyloid deposits by phagocytosis
    Renz M; Torres R; Dolan PJ; Tam SJ; Tapia JR; Li L; Salmans JR; Barbour RM; Shughrue PJ; Nijjar T; Schenk D; Kinney GG; Zago W
    Amyloid; 2016 Sep; 23(3):168-177. PubMed ID: 27494229
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.