BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 37866161)

  • 1. The SGK3-Catalase antioxidant signaling axis drives cervical cancer growth and therapy resistance.
    Wang M; Liu J; Liao X; Yi Y; Xue Y; Yang L; Cheng H; Liu P
    Redox Biol; 2023 Nov; 67():102931. PubMed ID: 37866161
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional role of SGK3 in PI3K/Pten driven liver tumor development.
    Cao H; Xu Z; Wang J; Cigliano A; Pilo MG; Ribback S; Zhang S; Qiao Y; Che L; Pascale RM; Calvisi DF; Chen X
    BMC Cancer; 2019 Apr; 19(1):343. PubMed ID: 30975125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.
    Bago R; Malik N; Munson MJ; Prescott AR; Davies P; Sommer E; Shpiro N; Ward R; Cross D; Ganley IG; Alessi DR
    Biochem J; 2014 Nov; 463(3):413-27. PubMed ID: 25177796
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.
    Pokorny D; Truebestein L; Fleming KD; Burke JE; Leonard TA
    J Biol Chem; 2021 Aug; 297(2):100919. PubMed ID: 34181950
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks.
    Malik N; Macartney T; Hornberger A; Anderson KE; Tovell H; Prescott AR; Alessi DR
    Biochem J; 2018 Jan; 475(1):117-135. PubMed ID: 29150437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
    Jiang W; He T; Liu S; Zheng Y; Xiang L; Pei X; Wang Z; Yang H
    J Hematol Oncol; 2018 Dec; 11(1):139. PubMed ID: 30547809
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of WNT/β-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations.
    Park YL; Kim HP; Cho YW; Min DW; Cheon SK; Lim YJ; Song SH; Kim SJ; Han SW; Park KJ; Kim TY
    Int J Cancer; 2019 Jan; 144(2):389-401. PubMed ID: 29978469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SGK3 sustains ERα signaling and drives acquired aromatase inhibitor resistance through maintaining endoplasmic reticulum homeostasis.
    Wang Y; Zhou D; Phung S; Warden C; Rashid R; Chan N; Chen S
    Proc Natl Acad Sci U S A; 2017 Feb; 114(8):E1500-E1508. PubMed ID: 28174265
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.
    Wang Y; Xu W; Zhou D; Neckers L; Chen S
    J Biol Chem; 2014 Feb; 289(8):4815-26. PubMed ID: 24379398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.
    Arjumand W; Merry CD; Wang C; Saba E; McIntyre JB; Fang S; Kornaga E; Ghatage P; Doll CM; Lees-Miller SP
    Oncotarget; 2016 Dec; 7(50):82424-82439. PubMed ID: 27489350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.
    Gasser JA; Inuzuka H; Lau AW; Wei W; Beroukhim R; Toker A
    Mol Cell; 2014 Nov; 56(4):595-607. PubMed ID: 25458846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serine/Threonine-Protein Kinase 3 Facilitates Myocardial Repair After Cardiac Injury Possibly Through the Glycogen Synthase Kinase-3β/β-Catenin Pathway.
    Li YF; Wei TW; Fan Y; Shan TK; Sun JT; Chen BR; Wang ZM; Gu LF; Yang TT; Liu L; Du C; Ma Y; Wang H; Sun R; Wei YY; Chen F; Guo XJ; Kong XQ; Wang LS
    J Am Heart Assoc; 2021 Nov; 10(22):e022802. PubMed ID: 34726469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader.
    Tovell H; Testa A; Zhou H; Shpiro N; Crafter C; Ciulli A; Alessi DR
    ACS Chem Biol; 2019 Sep; 14(9):2024-2034. PubMed ID: 31461270
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells.
    Wang Y; Zhou D; Phung S; Masri S; Smith D; Chen S
    Mol Endocrinol; 2011 Jan; 25(1):72-82. PubMed ID: 21084382
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer.
    Wang H; Huang F; Zhang Z; Wang P; Luo Y; Li H; Li N; Wang J; Zhou J; Wang Y; Li S
    Int J Biol Sci; 2019; 15(5):929-941. PubMed ID: 31182914
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
    Malik N; Nirujogi RS; Peltier J; Macartney T; Wightman M; Prescott AR; Gourlay R; Trost M; Alessi DR; Karapetsas A
    Biochem J; 2019 Oct; 476(20):3081-3107. PubMed ID: 31665227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.
    Bago R; Sommer E; Castel P; Crafter C; Bailey FP; Shpiro N; Baselga J; Cross D; Eyers PA; Alessi DR
    EMBO J; 2016 Sep; 35(17):1902-22. PubMed ID: 27481935
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells.
    Kim HJ; Lee SY; Kim CY; Kim YH; Ju W; Kim SC
    Oncotarget; 2017 Jan; 8(4):6608-6622. PubMed ID: 28036259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3.
    Tessier M; Woodgett JR
    J Biol Chem; 2006 Aug; 281(33):23978-89. PubMed ID: 16790420
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer.
    Wang M; Xue Y; Shen L; Qin P; Sang X; Tao Z; Yi J; Wang J; Liu P; Cheng H
    Redox Biol; 2019 Jun; 24():101225. PubMed ID: 31136958
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.