172 related articles for article (PubMed ID: 37870431)
1. Synthesis and Conformational Analysis of FR901464-Based RNA Splicing Modulators and Their Synergism in Drug-Resistant Cancers.
Beard JP; Bressin RK; Markaj PL; Schmitz JC; Koide K
J Med Chem; 2023 Nov; 66(21):14497-14512. PubMed ID: 37870431
[TBL] [Abstract][Full Text] [Related]
2. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells.
Albert BJ; McPherson PA; O'Brien K; Czaicki NL; Destefino V; Osman S; Li M; Day BW; Grabowski PJ; Moore MJ; Vogt A; Koide K
Mol Cancer Ther; 2009 Aug; 8(8):2308-18. PubMed ID: 19671752
[TBL] [Abstract][Full Text] [Related]
3. Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464.
Osman S; Albert BJ; Wang Y; Li M; Czaicki NL; Koide K
Chemistry; 2011 Jan; 17(3):895-904. PubMed ID: 21226105
[TBL] [Abstract][Full Text] [Related]
4. The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Finci LI; Zhang X; Huang X; Zhou Q; Tsai J; Teng T; Agrawal A; Chan B; Irwin S; Karr C; Cook A; Zhu P; Reynolds D; Smith PG; Fekkes P; Buonamici S; Larsen NA
Genes Dev; 2018 Feb; 32(3-4):309-320. PubMed ID: 29491137
[TBL] [Abstract][Full Text] [Related]
5. Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Teng T; Tsai JH; Puyang X; Seiler M; Peng S; Prajapati S; Aird D; Buonamici S; Caleb B; Chan B; Corson L; Feala J; Fekkes P; Gerard B; Karr C; Korpal M; Liu X; T Lowe J; Mizui Y; Palacino J; Park E; Smith PG; Subramanian V; Wu ZJ; Zou J; Yu L; Chicas A; Warmuth M; Larsen N; Zhu P
Nat Commun; 2017 May; 8():15522. PubMed ID: 28541300
[TBL] [Abstract][Full Text] [Related]
6. Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells.
Gao Y; Trivedi S; Ferris RL; Koide K
Sci Rep; 2014 Aug; 4():6098. PubMed ID: 25139387
[TBL] [Abstract][Full Text] [Related]
7. Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs.
Effenberger KA; Anderson DD; Bray WM; Prichard BE; Ma N; Adams MS; Ghosh AK; Jurica MS
J Biol Chem; 2014 Jan; 289(4):1938-47. PubMed ID: 24302718
[TBL] [Abstract][Full Text] [Related]
8. Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue.
Albert BJ; Sivaramakrishnan A; Naka T; Czaicki NL; Koide K
J Am Chem Soc; 2007 Mar; 129(9):2648-59. PubMed ID: 17279752
[TBL] [Abstract][Full Text] [Related]
9. Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae.
Hansen SR; Nikolai BJ; Spreacker PJ; Carrocci TJ; Hoskins AA
Cell Chem Biol; 2019 Mar; 26(3):443-448.e3. PubMed ID: 30639260
[TBL] [Abstract][Full Text] [Related]
10. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
Loerch S; Leach JR; Horner SW; Maji D; Jenkins JL; Pulvino MJ; Kielkopf CL
J Biol Chem; 2019 Feb; 294(8):2892-2902. PubMed ID: 30567737
[TBL] [Abstract][Full Text] [Related]
11. PHD finger protein 5A promoted lung adenocarcinoma progression via alternative splicing.
Mao S; Li Y; Lu Z; Che Y; Huang J; Lei Y; Wang Y; Liu C; Wang X; Zheng S; Sun N; He J
Cancer Med; 2019 May; 8(5):2429-2441. PubMed ID: 30932358
[TBL] [Abstract][Full Text] [Related]
12. Research progress and therapeutic prospect of PHF5A acting as a new target for malignant tumors.
Li M; Cheng Q; Wang X; Yang Y
Zhejiang Da Xue Xue Bao Yi Xue Ban; 2022 Nov; 51(5):647-655. PubMed ID: 36581580
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and antiproliferative activity of a tetrahydrofuran analog of FR901464.
Pohorilets I; Beard JP; Driscoll JL; Schmitz JC; Koide K
Bioorg Med Chem Lett; 2024 May; 104():129739. PubMed ID: 38599298
[TBL] [Abstract][Full Text] [Related]
14. Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells.
Gao Y; Koide K
ACS Chem Biol; 2013 May; 8(5):895-900. PubMed ID: 23485022
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of Splicing Factor 3b Subunit 1 (SF3B1) Reduced Cell Proliferation, Induced Apoptosis and Resulted in Cell Cycle Arrest by Regulating Homeobox A10 (HOXA10) Splicing in AGS and MKN28 Human Gastric Cancer Cells.
Zhang Y; Yuan Z; Jiang Y; Shen R; Gu M; Xu W; Gu X
Med Sci Monit; 2020 Jan; 26():e919460. PubMed ID: 31927557
[TBL] [Abstract][Full Text] [Related]
16. Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.
Sciarrillo R; Wojtuszkiewicz A; El Hassouni B; Funel N; Gandellini P; Lagerweij T; Buonamici S; Blijlevens M; Zeeuw van der Laan EA; Zaffaroni N; Deraco M; Kusamura S; Würdinger T; Peters GJ; Molthoff CFM; Jansen G; Kaspers GJL; Cloos J; Giovannetti E
EBioMedicine; 2019 Jan; 39():215-225. PubMed ID: 30581150
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of SF3B1 by molecules targeting the spliceosome results in massive aberrant exon skipping.
Wu G; Fan L; Edmonson MN; Shaw T; Boggs K; Easton J; Rusch MC; Webb TR; Zhang J; Potter PM
RNA; 2018 Aug; 24(8):1056-1066. PubMed ID: 29844105
[TBL] [Abstract][Full Text] [Related]
18. Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation.
Butt H; Bazin J; Alshareef S; Eid A; Benhamed M; Reddy ASN; Crespi M; Mahfouz MM
Commun Biol; 2021 May; 4(1):529. PubMed ID: 33953336
[TBL] [Abstract][Full Text] [Related]
19. Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.
Arai K; Buonamici S; Chan B; Corson L; Endo A; Gerard B; Hao MH; Karr C; Kira K; Lee L; Liu X; Lowe JT; Luo T; Marcaurelle LA; Mizui Y; Nevalainen M; O'Shea MW; Park ES; Perino SA; Prajapati S; Shan M; Smith PG; Tivitmahaisoon P; Wang JY; Warmuth M; Wu KM; Yu L; Zhang H; Zheng GZ; Keaney GF
Org Lett; 2014 Nov; 16(21):5560-3. PubMed ID: 25376106
[TBL] [Abstract][Full Text] [Related]
20. Investigating the Molecular Mechanism of H3B-8800: A Splicing Modulator Inducing Preferential Lethality in Spliceosome-Mutant Cancers.
Spinello A; Borišek J; Malcovati L; Magistrato A
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681880
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]