211 related articles for article (PubMed ID: 37871122)
1. Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo.
Kordus SL; Kroh HK; Rodríguez RC; Shrem RA; Peritore-Galve FC; Shupe JA; Wadzinski BE; Lacy DB; Spiller BW
PLoS Pathog; 2023 Oct; 19(10):e1011496. PubMed ID: 37871122
[TBL] [Abstract][Full Text] [Related]
2. Development and characterization of phage display-derived anti-toxin antibodies neutralizing TcdA and TcdB of
Raeisi H; Azimirad M; Asadzadeh Aghdaei H; Zarnani AH; Abdolalizadeh J; Yadegar A; Zali MR
Microbiol Spectr; 2023 Sep; 11(5):e0531022. PubMed ID: 37668373
[TBL] [Abstract][Full Text] [Related]
3. Neutralizing epitopes on
Chen B; Perry K; Jin R
Front Immunol; 2022; 13():978858. PubMed ID: 36466927
[TBL] [Abstract][Full Text] [Related]
4. Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections.
Carter GP; Chakravorty A; Pham Nguyen TA; Mileto S; Schreiber F; Li L; Howarth P; Clare S; Cunningham B; Sambol SP; Cheknis A; Figueroa I; Johnson S; Gerding D; Rood JI; Dougan G; Lawley TD; Lyras D
mBio; 2015 Jun; 6(3):e00551. PubMed ID: 26037121
[TBL] [Abstract][Full Text] [Related]
5. Study of the frequency of Clostridium difficile tcdA, tcdB, cdtA and cdtB genes in feces of Calves in south west of Iran.
Doosti A; Mokhtari-Farsani A
Ann Clin Microbiol Antimicrob; 2014 Jun; 13():21. PubMed ID: 24903619
[TBL] [Abstract][Full Text] [Related]
6. Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B.
Mansfield MJ; Tremblay BJ; Zeng J; Wei X; Hodgins H; Worley J; Bry L; Dong M; Doxey AC
PLoS Pathog; 2020 Dec; 16(12):e1009181. PubMed ID: 33370413
[TBL] [Abstract][Full Text] [Related]
7. Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models.
Tian JH; Glenn G; Flyer D; Zhou B; Liu Y; Sullivan E; Wu H; Cummings JF; Elllingsworth L; Smith G
Vaccine; 2017 Jul; 35(33):4079-4087. PubMed ID: 28669616
[TBL] [Abstract][Full Text] [Related]
8. Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.
Hernandez LD; Kroh HK; Hsieh E; Yang X; Beaumont M; Sheth PR; DiNunzio E; Rutherford SA; Ohi MD; Ermakov G; Xiao L; Secore S; Karczewski J; Racine F; Mayhood T; Fischer P; Sher X; Gupta P; Lacy DB; Therien AG
J Mol Biol; 2017 Apr; 429(7):1030-1044. PubMed ID: 28232034
[TBL] [Abstract][Full Text] [Related]
9. Use of a neutralizing antibody helps identify structural features critical for binding of
Kroh HK; Chandrasekaran R; Rosenthal K; Woods R; Jin X; Ohi MD; Nyborg AC; Rainey GJ; Warrener P; Spiller BW; Lacy DB
J Biol Chem; 2017 Sep; 292(35):14401-14412. PubMed ID: 28705932
[No Abstract] [Full Text] [Related]
10. Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B.
Simeon R; Jiang M; Chamoun-Emanuelli AM; Yu H; Zhang Y; Meng R; Peng Z; Jakana J; Zhang J; Feng H; Chen Z
PLoS Biol; 2019 Jun; 17(6):e3000311. PubMed ID: 31233493
[TBL] [Abstract][Full Text] [Related]
11. Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile.
Aminzadeh A; Tiwari MK; Mamah Mustapha SS; Navarrete SJ; Henriksen AB; Møller IM; Krogfelt KA; Bjerrum MJ; Jørgensen R
Free Radic Biol Med; 2020 Nov; 160():433-446. PubMed ID: 32860983
[TBL] [Abstract][Full Text] [Related]
12. Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain.
Hussack G; Arbabi-Ghahroudi M; van Faassen H; Songer JG; Ng KK; MacKenzie R; Tanha J
J Biol Chem; 2011 Mar; 286(11):8961-76. PubMed ID: 21216961
[TBL] [Abstract][Full Text] [Related]
13. A neutralizing antibody that blocks delivery of the enzymatic cargo of
Kroh HK; Chandrasekaran R; Zhang Z; Rosenthal K; Woods R; Jin X; Nyborg AC; Rainey GJ; Warrener P; Melnyk RA; Spiller BW; Lacy DB
J Biol Chem; 2018 Jan; 293(3):941-952. PubMed ID: 29180448
[No Abstract] [Full Text] [Related]
14. Human hypervirulent Clostridium difficile strains exhibit increased sporulation as well as robust toxin production.
Merrigan M; Venugopal A; Mallozzi M; Roxas B; Viswanathan VK; Johnson S; Gerding DN; Vedantam G
J Bacteriol; 2010 Oct; 192(19):4904-11. PubMed ID: 20675495
[TBL] [Abstract][Full Text] [Related]
15. Intrarectal instillation of Clostridium difficile toxin A triggers colonic inflammation and tissue damage: development of a novel and efficient mouse model of Clostridium difficile toxin exposure.
Hirota SA; Iablokov V; Tulk SE; Schenck LP; Becker H; Nguyen J; Al Bashir S; Dingle TC; Laing A; Liu J; Li Y; Bolstad J; Mulvey GL; Armstrong GD; MacNaughton WK; Muruve DA; MacDonald JA; Beck PL
Infect Immun; 2012 Dec; 80(12):4474-84. PubMed ID: 23045481
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
Orth P; Xiao L; Hernandez LD; Reichert P; Sheth PR; Beaumont M; Yang X; Murgolo N; Ermakov G; DiNunzio E; Racine F; Karczewski J; Secore S; Ingram RN; Mayhood T; Strickland C; Therien AG
J Biol Chem; 2014 Jun; 289(26):18008-21. PubMed ID: 24821719
[TBL] [Abstract][Full Text] [Related]
17. A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile.
Zhang BZ; Cai J; Yu B; Hua Y; Lau CC; Kao RY; Sze KH; Yuen KY; Huang JD
BMC Infect Dis; 2016 Oct; 16(1):596. PubMed ID: 27770789
[TBL] [Abstract][Full Text] [Related]
18. Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile.
Murase T; Eugenio L; Schorr M; Hussack G; Tanha J; Kitova EN; Klassen JS; Ng KK
J Biol Chem; 2014 Jan; 289(4):2331-43. PubMed ID: 24311789
[TBL] [Abstract][Full Text] [Related]
19. Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from
Paparella AS; Brew I; Hong HA; Ferriera W; Cutting S; Lamiable-Oulaidi F; Popadynec M; Tyler PC; Schramm VL
ACS Infect Dis; 2024 Mar; 10(3):928-937. PubMed ID: 38334357
[No Abstract] [Full Text] [Related]
20. Sequence variation in tcdA and tcdB of Clostridium difficile: ST37 with truncated tcdA is a potential epidemic strain in China.
Du P; Cao B; Wang J; Li W; Jia H; Zhang W; Lu J; Li Z; Yu H; Chen C; Cheng Y
J Clin Microbiol; 2014 Sep; 52(9):3264-70. PubMed ID: 24958798
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]