BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 37877348)

  • 1. Restoration of p53 functions by suppression of mortalin-p53 sequestration: an emerging target in cancer therapy.
    Shankaranarayana AH; Meduri B; Pujar GV; Hariharapura RC; Sethu AK; Singh M; Bidye D
    Future Med Chem; 2023 Nov; 15(22):2087-2112. PubMed ID: 37877348
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mortalin - a multipotent chaperone regulating cellular processes ranging from viral infection to neurodegeneration.
    Flachbartová Z; Kovacech B
    Acta Virol; 2013; 57(1):3-15. PubMed ID: 23530819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells.
    Sane S; Abdullah A; Boudreau DA; Autenried RK; Gupta BK; Wang X; Wang H; Schlenker EH; Zhang D; Telleria C; Huang L; Chauhan SC; Rezvani K
    Cell Death Dis; 2014 Mar; 5(3):e1118. PubMed ID: 24625977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells.
    Starenki D; Hong SK; Lloyd RV; Park JI
    Oncogene; 2015 Aug; 34(35):4624-34. PubMed ID: 25435367
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.
    Gestl EE; Anne Böttger S
    Biochem Biophys Res Commun; 2012 Jun; 423(2):411-6. PubMed ID: 22683628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas.
    Klaus C; Kaemmerer E; Reinartz A; Schneider U; Plum P; Jeon MK; Hose J; Hartmann F; Schnölzer M; Wagner N; Kopitz J; Gassler N
    Cell Tissue Res; 2014 Jul; 357(1):267-78. PubMed ID: 24770931
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mortalin (HSPA9) facilitates
    Wu PK; Hong SK; Chen W; Becker AE; Gundry RL; Lin CW; Shao H; Gestwicki JE; Park JI
    Sci Signal; 2020 Mar; 13(622):. PubMed ID: 32156782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
    Starenki D; Sosonkina N; Hong SK; Lloyd RV; Park JI
    Int J Mol Sci; 2019 Apr; 20(9):. PubMed ID: 31027376
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and functional characterization of nuclear mortalin in human carcinogenesis.
    Ryu J; Kaul Z; Yoon AR; Liu Y; Yaguchi T; Na Y; Ahn HM; Gao R; Choi IK; Yun CO; Kaul SC; Wadhwa R
    J Biol Chem; 2014 Sep; 289(36):24832-44. PubMed ID: 25012652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability.
    Wu PK; Hong SK; Starenki D; Oshima K; Shao H; Gestwicki JE; Tsai S; Park JI
    Oncogene; 2020 May; 39(21):4257-4270. PubMed ID: 32291414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein.
    Wadhwa R; Yaguchi T; Hasan MK; Mitsui Y; Reddel RR; Kaul SC
    Exp Cell Res; 2002 Apr; 274(2):246-53. PubMed ID: 11900485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mortalin/HSPA9-mediated switch in tumor-suppressive signaling of Raf/MEK/extracellular signal-regulated kinase.
    Wu PK; Hong SK; Veeranki S; Karkhanis M; Starenki D; Plaza JA; Park JI
    Mol Cell Biol; 2013 Oct; 33(20):4051-67. PubMed ID: 23959801
    [TBL] [Abstract][Full Text] [Related]  

  • 13. METTL3-mediated HSPA9 m6A modification promotes malignant transformation and inhibits cellular senescence by regulating exosomal mortalin protein in cervical cancer.
    Ao K; Yin M; Lyu X; Xiao Y; Chen X; Zhong S; Wen X; Yuan J; Ye M; Zhang J; Li X; Hao Y; Guo X
    Cancer Lett; 2024 Apr; 587():216658. PubMed ID: 38253218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53.
    Ramraj SK; Elayapillai SP; Pelikan RC; Zhao YD; Isingizwe ZR; Kennedy AL; Lightfoot SA; Benbrook DM
    Int J Cancer; 2020 Aug; 147(4):1086-1097. PubMed ID: 31845320
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells.
    Butler C; Dunmire M; Choi J; Szalai G; Johnson A; Lei W; Chen X; Liu L; Li W; Walter MJ; Liu T
    Cell Stress Chaperones; 2024 Apr; 29(2):300-311. PubMed ID: 38508444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model.
    Walker C; Böttger S; Low B
    Am J Pathol; 2006 May; 168(5):1526-30. PubMed ID: 16651619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Abrogating the Interaction Between p53 and Mortalin (Grp75/HSPA9/mtHsp70) for Cancer Therapy: The Story so far.
    Elwakeel A
    Front Cell Dev Biol; 2022; 10():879632. PubMed ID: 35493098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Withanone binds to mortalin and abrogates mortalin-p53 complex: computational and experimental evidence.
    Grover A; Priyandoko D; Gao R; Shandilya A; Widodo N; Bisaria VS; Kaul SC; Wadhwa R; Sundar D
    Int J Biochem Cell Biol; 2012 Mar; 44(3):496-504. PubMed ID: 22155302
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides.
    Kaul SC; Aida S; Yaguchi T; Kaur K; Wadhwa R
    J Biol Chem; 2005 Nov; 280(47):39373-9. PubMed ID: 16176931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins--identification of additional interacting regions.
    Iosefson O; Azem A
    FEBS Lett; 2010 Mar; 584(6):1080-4. PubMed ID: 20153329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.