BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 37883842)

  • 1. Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency.
    Piroli GG; Manuel AM; McCain RS; Smith HH; Ozohanics O; Mellid S; Cox JH; Cotham WE; Walla MD; Cascón A; Ambrus A; Frizzell N
    Redox Biol; 2023 Nov; 67():102932. PubMed ID: 37883842
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.
    Piroli GG; Manuel AM; Clapper AC; Walla MD; Baatz JE; Palmiter RD; Quintana A; Frizzell N
    Mol Cell Proteomics; 2016 Feb; 15(2):445-61. PubMed ID: 26450614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.
    Kiss G; Konrad C; Doczi J; Starkov AA; Kawamata H; Manfredi G; Zhang SF; Gibson GE; Beal MF; Adam-Vizi V; Chinopoulos C
    FASEB J; 2013 Jun; 27(6):2392-406. PubMed ID: 23475850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines.
    Gibson GE; Xu H; Chen HL; Chen W; Denton TT; Zhang S
    J Neurochem; 2015 Jul; 134(1):86-96. PubMed ID: 25772995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.
    Kiss G; Konrad C; Pour-Ghaz I; Mansour JJ; Németh B; Starkov AA; Adam-Vizi V; Chinopoulos C
    FASEB J; 2014 Apr; 28(4):1682-97. PubMed ID: 24391134
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins.
    Yang L; Shi Q; Ho DJ; Starkov AA; Wille EJ; Xu H; Chen HL; Zhang S; Stack CM; Calingasan NY; Gibson GE; Beal MF
    Neurobiol Dis; 2009 Nov; 36(2):320-30. PubMed ID: 19660549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
    Anderson NM; Qin X; Finan JM; Lam A; Athoe J; Missiaen R; Skuli N; Kennedy A; Saini AS; Tao T; Zhu S; Nissim I; Look AT; Qing G; Simon MC; Feng H
    Cancer Res; 2021 Sep; 81(17):4417-4430. PubMed ID: 34233924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenesis of conserved active site residues of dihydrolipoamide succinyltransferase enhances the accumulation of α-ketoglutarate in Yarrowia lipolytica.
    Guo H; Madzak C; Du G; Zhou J
    Appl Microbiol Biotechnol; 2016 Jan; 100(2):649-59. PubMed ID: 26428234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation.
    Dobolyi A; Bago A; Palkovits M; Nemeria NS; Jordan F; Doczi J; Ambrus A; Adam-Vizi V; Chinopoulos C
    Brain Struct Funct; 2020 Mar; 225(2):639-667. PubMed ID: 31982949
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Brain [U-13 C]glucose metabolism in mice with decreased α-ketoglutarate dehydrogenase complex activity.
    Nilsen LH; Shi Q; Gibson GE; Sonnewald U
    J Neurosci Res; 2011 Dec; 89(12):1997-2007. PubMed ID: 21374701
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Consequences of the α-ketoglutarate dehydrogenase inhibition for neuronal metabolism and survival: implications for neurodegenerative diseases.
    Trofimova LK; Araújo WL; Strokina AA; Fernie AR; Bettendorff L; Bunik VI
    Curr Med Chem; 2012; 19(34):5895-906. PubMed ID: 23061627
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reverse and Forward Electron Flow-Induced H
    Horváth G; Sváb G; Komlódi T; Ravasz D; Kacsó G; Doczi J; Chinopoulos C; Ambrus A; Tretter L
    Antioxidants (Basel); 2022 Jul; 11(8):. PubMed ID: 36009207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle.
    Komlódi T; Tretter L
    Neuropharmacology; 2017 Sep; 123():287-298. PubMed ID: 28495375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition.
    Dumont M; Ho DJ; Calingasan NY; Xu H; Gibson G; Beal MF
    Free Radic Biol Med; 2009 Oct; 47(7):1019-27. PubMed ID: 19596066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Brain regional development of the activity of alpha-ketoglutarate dehydrogenase complex in the rat.
    Buerstatte CR; Behar KL; Novotny EJ; Lai JC
    Brain Res Dev Brain Res; 2000 Dec; 125(1-2):139-45. PubMed ID: 11154769
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain.
    Kayser EB; Sedensky MM; Morgan PG
    PLoS One; 2016; 11(1):e0148219. PubMed ID: 26824698
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease.
    Johnson SC; Kayser EB; Bornstein R; Stokes J; Bitto A; Park KY; Pan A; Sun G; Raftery D; Kaeberlein M; Sedensky MM; Morgan PG
    Mol Genet Metab; 2020 Jun; 130(2):118-132. PubMed ID: 32331968
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Short-term regulation of the alpha-ketoglutarate dehydrogenase complex by energy-linked and some other effectors.
    Strumilo S
    Biochemistry (Mosc); 2005 Jul; 70(7):726-9. PubMed ID: 16097935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors.
    Lai JC; Cooper AJ
    J Neurochem; 1986 Nov; 47(5):1376-86. PubMed ID: 3760866
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts.
    Valsecchi F; Monge C; Forkink M; de Groof AJ; Benard G; Rossignol R; Swarts HG; van Emst-de Vries SE; Rodenburg RJ; Calvaruso MA; Nijtmans LG; Heeman B; Roestenberg P; Wieringa B; Smeitink JA; Koopman WJ; Willems PH
    Biochim Biophys Acta; 2012 Oct; 1817(10):1925-36. PubMed ID: 22430089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.