BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 37887305)

  • 1. lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons.
    Provasek VE; Kodavati M; Guo W; Wang H; Boldogh I; Van Den Bosch L; Britz G; Hegde ML
    Cells; 2023 Oct; 12(20):. PubMed ID: 37887305
    [TBL] [Abstract][Full Text] [Related]  

  • 2. lncRNA Sequencing Reveals Neurodegeneration-associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists In Motor Neurons.
    Provasek VE; Kodavati M; Guo W; Wang H; Boldogh I; Van Den Bosch L; Britz G; Hegde M
    Res Sq; 2023 Jun; ():. PubMed ID: 37461717
    [No Abstract]   [Full Text] [Related]  

  • 3. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
    Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
    Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
    Zhu Y; Burg T; Neyrinck K; Vervliet T; Nami F; Vervoort E; Ahuja K; Sassano ML; Chai YC; Tharkeshwar AK; De Smedt J; Hu H; Bultynck G; Agostinis P; Swinnen JV; Van Den Bosch L; da Costa RFM; Verfaillie C
    Acta Neuropathol; 2024 Jan; 147(1):6. PubMed ID: 38170217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
    Lenzi J; De Santis R; de Turris V; Morlando M; Laneve P; Calvo A; Caliendo V; Chiò A; Rosa A; Bozzoni I
    Dis Model Mech; 2015 Jul; 8(7):755-66. PubMed ID: 26035390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.
    Nishimoto Y; Nakagawa S; Hirose T; Okano HJ; Takao M; Shibata S; Suyama S; Kuwako K; Imai T; Murayama S; Suzuki N; Okano H
    Mol Brain; 2013 Jul; 6():31. PubMed ID: 23835137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
    Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
    Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Generation of two induced pluripotent stem cell lines with heterozygous and homozygous amyotrophic lateral sclerosis-causing mutation P525L (c.1574C > T) in FUS gene.
    Akter M; Cui H; Abir Hosain M; Ding B
    Stem Cell Res; 2023 Jun; 69():103103. PubMed ID: 37116345
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
    Ichiyanagi N; Fujimori K; Yano M; Ishihara-Fujisaki C; Sone T; Akiyama T; Okada Y; Akamatsu W; Matsumoto T; Ishikawa M; Nishimoto Y; Ishihara Y; Sakuma T; Yamamoto T; Tsuiji H; Suzuki N; Warita H; Aoki M; Okano H
    Stem Cell Reports; 2016 Apr; 6(4):496-510. PubMed ID: 26997647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
    Groen EJ; Fumoto K; Blokhuis AM; Engelen-Lee J; Zhou Y; van den Heuvel DM; Koppers M; van Diggelen F; van Heest J; Demmers JA; Kirby J; Shaw PJ; Aronica E; Spliet WG; Veldink JH; van den Berg LH; Pasterkamp RJ
    Hum Mol Genet; 2013 Sep; 22(18):3690-704. PubMed ID: 23681068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis.
    De Santis R; Santini L; Colantoni A; Peruzzi G; de Turris V; Alfano V; Bozzoni I; Rosa A
    Stem Cell Reports; 2017 Nov; 9(5):1450-1462. PubMed ID: 28988989
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.
    Wang L; Yi F; Fu L; Yang J; Wang S; Wang Z; Suzuki K; Sun L; Xu X; Yu Y; Qiao J; Belmonte JCI; Yang Z; Yuan Y; Qu J; Liu GH
    Protein Cell; 2017 May; 8(5):365-378. PubMed ID: 28401346
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11.
    Hedges EC; Topp S; Shaw CE; Nishimura AL
    Stem Cell Res; 2021 Apr; 52():102246. PubMed ID: 33610019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Homozygous ALS-linked FUS P525L mutations cell- autonomously perturb transcriptome profile and chemoreceptor signaling in human iPSC microglia.
    Kerk SY; Bai Y; Smith J; Lalgudi P; Hunt C; Kuno J; Nuara J; Yang T; Lanza K; Chan N; Coppola A; Tang Q; Espert J; Jones H; Fannell C; Zambrowicz B; Chiao E
    Stem Cell Reports; 2022 Mar; 17(3):678-692. PubMed ID: 35120624
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
    Shum C; Hedges EC; Allison J; Lee YB; Arias N; Cocks G; Chandran S; Ruepp MD; Shaw CE; Nishimura AL
    Stem Cell Reports; 2024 Feb; 19(2):187-195. PubMed ID: 38242131
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
    Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
    Akiyama T; Suzuki N; Ishikawa M; Fujimori K; Sone T; Kawada J; Funayama R; Fujishima F; Mitsuzawa S; Ikeda K; Ono H; Shijo T; Osana S; Shirota M; Nakagawa T; Kitajima Y; Nishiyama A; Izumi R; Morimoto S; Okada Y; Kamei T; Nishida M; Nogami M; Kaneda S; Ikeuchi Y; Mitsuhashi H; Nakayama K; Fujii T; Warita H; Okano H; Aoki M
    EBioMedicine; 2019 Jul; 45():362-378. PubMed ID: 31262712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
    Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
    Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
    Guo W; Naujock M; Fumagalli L; Vandoorne T; Baatsen P; Boon R; Ordovás L; Patel A; Welters M; Vanwelden T; Geens N; Tricot T; Benoy V; Steyaert J; Lefebvre-Omar C; Boesmans W; Jarpe M; Sterneckert J; Wegner F; Petri S; Bohl D; Vanden Berghe P; Robberecht W; Van Damme P; Verfaillie C; Van Den Bosch L
    Nat Commun; 2017 Oct; 8(1):861. PubMed ID: 29021520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.