BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 37890199)

  • 1. The discovery of water-soluble indazole derivatives as potent microtubule polymerization inhibitors.
    Cui YJ; Zhou Y; Zhang XW; Dou BK; Ma CC; Zhang J
    Eur J Med Chem; 2023 Dec; 262():115870. PubMed ID: 37890199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
    Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Indazole-based microtubule-targeting agents as potential candidates for anticancer drugs discovery.
    Pal D; Song IH; Dashrath Warkad S; Song KS; Seong Yeom G; Saha S; Shinde PB; Balasaheb Nimse S
    Bioorg Chem; 2022 May; 122():105735. PubMed ID: 35298962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
    Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.
    Song J; Wang SH; Song CH; Zhang WX; Zhu JX; Tian XY; Fu XJ; Xu Y; Jin CY; Zhang SY
    Eur J Med Chem; 2022 Oct; 240():114583. PubMed ID: 35834904
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis.
    Deng S; Banerjee S; Chen H; Pochampally S; Wang Y; Yun MK; White SW; Parmar K; Meibohm B; Hartman KL; Wu Z; Miller DD; Li W
    Cancer Lett; 2023 Feb; 555():216046. PubMed ID: 36596380
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
    Lin S; Du T; Zhang J; Wu D; Tian H; Zhang K; Jiang L; Lu D; Sheng L; Li Y; Ji M; Chen X; Xu H
    J Med Chem; 2022 Dec; 65(24):16372-16391. PubMed ID: 36511661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
    Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
    Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities.
    Song J; Guan YF; Liu WB; Song CH; Tian XY; Zhu T; Fu XJ; Qi YQ; Zhang SY
    Eur J Med Chem; 2022 Aug; 238():114467. PubMed ID: 35605363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
    Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
    Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
    Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G; Wang Y; Li L; Ren Y; Deng X; Liu J; Wang W; Luo M; Liu S; Chen J
    Eur J Med Chem; 2020 Sep; 202():112519. PubMed ID: 32650183
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Novel
    Leng J; Zhao Y; Sheng P; Xia Y; Chen T; Zhao S; Xie S; Yan X; Wang X; Yin Y; Kong L
    J Med Chem; 2022 Dec; 65(24):16774-16800. PubMed ID: 36471625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and biological evaluation of 4,6-pyrimidine analogues with potential anticancer agents as novel colchicine binding site inhibitors.
    Zhang J; Tan L; Wu C; Li Y; Chen H; Liu Y; Wang Y
    Eur J Med Chem; 2023 Feb; 248():115085. PubMed ID: 36621138
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SAR Investigation and Discovery of Water-Soluble 1-Methyl-1,4-dihydroindeno[1,2-
    Cui YJ; Liu C; Ma CC; Ji YT; Yao YL; Tang LQ; Zhang CM; Wu JD; Liu ZP
    J Med Chem; 2020 Dec; 63(23):14840-14866. PubMed ID: 33201714
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.
    Li CM; Lu Y; Chen J; Costello TA; Narayanan R; Dalton MN; Snyder LM; Ahn S; Li W; Miller DD; Dalton JT
    Pharm Res; 2012 Nov; 29(11):3053-63. PubMed ID: 22760659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
    Guo Q; Zhang H; Deng Y; Zhai S; Jiang Z; Zhu D; Wang L
    Eur J Med Chem; 2020 Jun; 196():112328. PubMed ID: 32320841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells.
    Wu H; Wang LS; Li P; Yu J; Cheng S; Yu G; Ahmad M; Meng XL; Luo H; Xu BX
    Eur J Med Chem; 2023 Aug; 256():115470. PubMed ID: 37201429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of novel 2-(trifluoromethyl)quinolin-4-amine derivatives as potent antitumor agents with microtubule polymerization inhibitory activity.
    Liu K; Mo M; Yu G; Yu J; Song SM; Cheng S; Li HM; Meng XL; Zeng XP; Xu GC; Luo H; Xu BX
    Bioorg Chem; 2023 Oct; 139():106727. PubMed ID: 37451147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.