BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 37897437)

  • 1. Deciphering Interactions between Potential Inhibitors and the
    Lima Costa AH; Bezerra KS; de Lima Neto JX; Oliveira JIN; Galvão DS; Fulco UL
    J Phys Chem B; 2023 Nov; 127(44):9461-9475. PubMed ID: 37897437
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recent advances on patents of
    Gehlot P; Vyas VK
    Expert Opin Ther Pat; 2023; 33(9):579-596. PubMed ID: 37942637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.
    Ross LS; Gamo FJ; Lafuente-Monasterio MJ; Singh OM; Rowland P; Wiegand RC; Wirth DF
    J Biol Chem; 2014 Jun; 289(26):17980-95. PubMed ID: 24782313
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
    Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
    Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dihydroorotate dehydrogenase: A drug target for the development of antimalarials.
    Singh A; Maqbool M; Mobashir M; Hoda N
    Eur J Med Chem; 2017 Jan; 125():640-651. PubMed ID: 27721149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
    Azeredo LFSP; Coutinho JP; Jabor VAP; Feliciano PR; Nonato MC; Kaiser CR; Menezes CMS; Hammes ASO; Caffarena ER; Hoelz LVB; de Souza NB; Pereira GAN; Cerávolo IP; Krettli AU; Boechat N
    Eur J Med Chem; 2017 Jan; 126():72-83. PubMed ID: 27744189
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of 3,4-Dihydro-2
    Hartuti ED; Sakura T; Tagod MSO; Yoshida E; Wang X; Mochizuki K; Acharjee R; Matsuo Y; Tokumasu F; Mori M; Waluyo D; Shiomi K; Nozaki T; Hamano S; Shiba T; Kita K; Inaoka DK
    Int J Mol Sci; 2021 Jul; 22(13):. PubMed ID: 34281290
    [No Abstract]   [Full Text] [Related]  

  • 8. A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds.
    Sharma M; Pandey V; Poli G; Tuccinardi T; Lolli ML; Vyas VK
    Bioorg Chem; 2024 May; 146():107249. PubMed ID: 38493638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of the Intramolecular Hydrogen Bond on the Active Metabolite Analogs of Leflunomide for Blocking the Plasmodium falciparum Dihydroorotate Dehydrogenase Enzyme: QTAIM, NBO, and Docking Study.
    Heidarian R; Zahedi-Tabrizi M
    Curr Comput Aided Drug Des; 2021; 17(3):480-491. PubMed ID: 32459610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum.
    Dickerman BK; Elsworth B; Cobbold SA; Nie CQ; McConville MJ; Crabb BS; Gilson PR
    Sci Rep; 2016 Nov; 6():37502. PubMed ID: 27874068
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of dual-target natural antimalarial agents against DHODH and PMT of
    Elamin EM; Eshage SE; Mohmmode SM; Mukhtar RM; Mahjoub M; Sadelin E; Shoaib TH; Edris A; Elshamly EM; Makki AA; Ashour A; Sherif AE; Osman W; Ibrahim SRM; Mohamed GA; Alzain AA
    SAR QSAR Environ Res; 2023; 34(9):709-728. PubMed ID: 37665563
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity.
    Kokkonda S; Deng X; White KL; Coteron JM; Marco M; de Las Heras L; White J; El Mazouni F; Tomchick DR; Manjalanagara K; Rudra KR; Chen G; Morizzi J; Ryan E; Kaminsky W; Leroy D; Martínez-Martínez MS; Jimenez-Diaz MB; Bazaga SF; Angulo-Barturen I; Waterson D; Burrows JN; Matthews D; Charman SA; Phillips MA; Rathod PK
    J Med Chem; 2016 Jun; 59(11):5416-31. PubMed ID: 27127993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance.
    Mandt REK; Luth MR; Tye MA; Mazitschek R; Ottilie S; Winzeler EA; Lafuente-Monasterio MJ; Gamo FJ; Wirth DF; Lukens AK
    Elife; 2023 Sep; 12():. PubMed ID: 37737220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. QSAR study on the antimalarial activity of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors.
    Hou X; Chen X; Zhang M; Yan A
    SAR QSAR Environ Res; 2016; 27(2):101-24. PubMed ID: 26911561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
    Pippione AC; Sainas S; Goyal P; Fritzson I; Cassiano GC; Giraudo A; Giorgis M; Tavella TA; Bagnati R; Rolando B; Caing-Carlsson R; Costa FTM; Andrade CH; Al-Karadaghi S; Boschi D; Friemann R; Lolli ML
    Eur J Med Chem; 2019 Feb; 163():266-280. PubMed ID: 30529545
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CF
    Agoni C; Salifu EY; Munsamy G; Olotu FA; Soliman M
    Chem Biodivers; 2019 Dec; 16(12):e1900365. PubMed ID: 31589372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones.
    Clark RD; Morris DN; Chinigo G; Lawless MS; Prudhomme J; Le Roch KG; Lafuente MJ; Ferrer S; Gamo FJ; Gadwood R; Woltosz WS
    J Comput Aided Mol Des; 2020 Nov; 34(11):1117-1132. PubMed ID: 32833084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
    Palmer MJ; Deng X; Watts S; Krilov G; Gerasyuto A; Kokkonda S; El Mazouni F; White J; White KL; Striepen J; Bath J; Schindler KA; Yeo T; Shackleford DM; Mok S; Deni I; Lawong A; Huang A; Chen G; Wang W; Jayaseelan J; Katneni K; Patil R; Saunders J; Shahi SP; Chittimalla R; Angulo-Barturen I; Jiménez-Díaz MB; Wittlin S; Tumwebaze PK; Rosenthal PJ; Cooper RA; Aguiar ACC; Guido RVC; Pereira DB; Mittal N; Winzeler EA; Tomchick DR; Laleu B; Burrows JN; Rathod PK; Fidock DA; Charman SA; Phillips MA
    J Med Chem; 2021 May; 64(9):6085-6136. PubMed ID: 33876936
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds.
    Deng X; Gujjar R; El Mazouni F; Kaminsky W; Malmquist NA; Goldsmith EJ; Rathod PK; Phillips MA
    J Biol Chem; 2009 Sep; 284(39):26999-7009. PubMed ID: 19640844
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
    White J; Dhingra SK; Deng X; El Mazouni F; Lee MCS; Afanador GA; Lawong A; Tomchick DR; Ng CL; Bath J; Rathod PK; Fidock DA; Phillips MA
    ACS Infect Dis; 2019 Jan; 5(1):90-101. PubMed ID: 30375858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.