BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 37897437)

  • 21. Recent developments in the medicinal chemistry and therapeutic potential of dihydroorotate dehydrogenase (DHODH) inhibitors.
    Vyas VK; Ghate M
    Mini Rev Med Chem; 2011 Oct; 11(12):1039-55. PubMed ID: 21861807
    [TBL] [Abstract][Full Text] [Related]  

  • 22. In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model.
    Mandt REK; Lafuente-Monasterio MJ; Sakata-Kato T; Luth MR; Segura D; Pablos-Tanarro A; Viera S; Magan N; Ottilie S; Winzeler EA; Lukens AK; Gamo FJ; Wirth DF
    Sci Transl Med; 2019 Dec; 11(521):. PubMed ID: 31801884
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors.
    Deng X; Kokkonda S; El Mazouni F; White J; Burrows JN; Kaminsky W; Charman SA; Matthews D; Rathod PK; Phillips MA
    J Med Chem; 2014 Jun; 57(12):5381-94. PubMed ID: 24801997
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives.
    Xu M; Zhu J; Diao Y; Zhou H; Ren X; Sun D; Huang J; Han D; Zhao Z; Zhu L; Xu Y; Li H
    J Med Chem; 2013 Oct; 56(20):7911-24. PubMed ID: 24073986
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice.
    Gujjar R; Marwaha A; El Mazouni F; White J; White KL; Creason S; Shackleford DM; Baldwin J; Charman WN; Buckner FS; Charman S; Rathod PK; Phillips MA
    J Med Chem; 2009 Apr; 52(7):1864-72. PubMed ID: 19296651
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
    Kokkonda S; Deng X; White KL; El Mazouni F; White J; Shackleford DM; Katneni K; Chiu FCK; Barker H; McLaren J; Crighton E; Chen G; Angulo-Barturen I; Jimenez-Diaz MB; Ferrer S; Huertas-Valentin L; Martinez-Martinez MS; Lafuente-Monasterio MJ; Chittimalla R; Shahi SP; Wittlin S; Waterson D; Burrows JN; Matthews D; Tomchick D; Rathod PK; Palmer MJ; Charman SA; Phillips MA
    J Med Chem; 2020 May; 63(9):4929-4956. PubMed ID: 32248693
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979.
    Pramisandi A; Dobashi K; Mori M; Nonaka K; Matsumoto A; Tokiwa T; Higo M; Kristiningrum ; Amalia E; Nurkanto A; Inaoka DK; Waluyo D; Kita K; Nozaki T; Ōmura S; Shiomi K
    J Gen Appl Microbiol; 2020 Nov; 66(5):273-278. PubMed ID: 32669511
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase.
    Lang L; Hu Q; Wang J; Liu Z; Huang J; Lu W; Huang Y
    Chem Biol Drug Des; 2018 Jul; 92(1):1324-1332. PubMed ID: 29582555
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis, Design, and Structure⁻Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of
    Xu L; Li W; Diao Y; Sun H; Li H; Zhu L; Zhou H; Zhao Z
    Molecules; 2018 May; 23(6):. PubMed ID: 29794978
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum.
    Ross LS; Lafuente-Monasterio MJ; Sakata-Kato T; Mandt REK; Gamo FJ; Wirth DF; Lukens AK
    ACS Infect Dis; 2018 Apr; 4(4):508-515. PubMed ID: 29336544
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase.
    Boa AN; Canavan SP; Hirst PR; Ramsey C; Stead AM; McConkey GA
    Bioorg Med Chem; 2005 Mar; 13(6):1945-67. PubMed ID: 15727850
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Novel inhibitors of the Plasmodium falciparum electron transport chain.
    Stocks PA; Barton V; Antoine T; Biagini GA; Ward SA; O'Neill PM
    Parasitology; 2014 Jan; 141(1):50-65. PubMed ID: 24401337
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Gentisyl alcohol and homogentisic acid: Plasmodium falciparum dihydroorotate dehydrogenase inhibitors isolated from fungi.
    Pramisandi A; Kurnia K; Chrisnayanti E; Bernawati P; Dobashi K; Mori M; Mahsunah AH; Nonaka K; Matsumoto A; Kristiningrum ; Hidayati DN; Dewi D; Prabandari EE; Amalia E; Rahmawati Y; Nurkanto A; Inaoka DK; Waluyo D; Kita K; Nozaki T; Ōmura S; Shiomi K
    J Gen Appl Microbiol; 2021 Jul; 67(3):114-117. PubMed ID: 33814517
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In-Silico molecular docking and simulation studies on novel chalcone and flavone hybrid derivatives with 1, 2, 3-triazole linkage as vital inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
    Thillainayagam M; Malathi K; Ramaiah S
    J Biomol Struct Dyn; 2018 Nov; 36(15):3993-4009. PubMed ID: 29132266
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening.
    Pavadai E; El Mazouni F; Wittlin S; de Kock C; Phillips MA; Chibale K
    J Chem Inf Model; 2016 Mar; 56(3):548-62. PubMed ID: 26915022
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
    Silveira FF; de Souza JO; Hoelz LVB; Campos VR; Jabor VAP; Aguiar ACC; Nonato MC; Albuquerque MG; Guido RVC; Boechat N; Pinheiro LCS
    Eur J Med Chem; 2021 Jan; 209():112941. PubMed ID: 33158577
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor.
    Hurt DE; Widom J; Clardy J
    Acta Crystallogr D Biol Crystallogr; 2006 Mar; 62(Pt 3):312-23. PubMed ID: 16510978
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Tetrahydro-1H,5H-pyrazolo[1,2-a]pyrazole-1-carboxylates as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
    Strašek N; Lavrenčič L; Oštrek A; Slapšak D; Grošelj U; Klemenčič M; Brodnik Žugelj H; Wagger J; Novinec M; Svete J
    Bioorg Chem; 2019 Aug; 89():102982. PubMed ID: 31132601
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Chemometric modeling, docking and in silico design of triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors as antimalarials.
    Ojha PK; Roy K
    Eur J Med Chem; 2010 Oct; 45(10):4645-56. PubMed ID: 20708304
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In silico identification of novel inhibitors against Plasmodium falciparum dihydroorate dehydrogenase.
    Wadood A; Ulhaq ZU
    J Mol Graph Model; 2013 Mar; 40():40-7. PubMed ID: 23353582
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.