154 related articles for article (PubMed ID: 37901516)
1. Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-
Yang X; Ong HW; Dickmander RJ; Smith JL; Brown JW; Tao W; Chang E; Moorman NJ; Axtman AD; Willson TM
ACS Omega; 2023 Oct; 8(42):39546-39561. PubMed ID: 37901516
[TBL] [Abstract][Full Text] [Related]
2. Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2A.
Yang X; Ong HW; Dickmander RJ; Smith JL; Brown JW; Tao W; Chang E; Moorman NJ; Axtman AD; Willson TM
bioRxiv; 2023 Jul; ():. PubMed ID: 37292607
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity.
Asressu KH; Smith JL; Dickmander RJ; Moorman NJ; Wellnitz J; Popov KI; Axtman AD; Willson TM
Pharmaceuticals (Basel); 2024 Feb; 17(3):. PubMed ID: 38543092
[TBL] [Abstract][Full Text] [Related]
4. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor.
Krämer A; Kurz CG; Berger BT; Celik IE; Tjaden A; Greco FA; Knapp S; Hanke T
Eur J Med Chem; 2020 Dec; 208():112770. PubMed ID: 32883634
[TBL] [Abstract][Full Text] [Related]
5. Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3.
Galal KA; Krämer A; Strickland BG; Smith JL; Dickmander RJ; Moorman NJ; Willson TM
bioRxiv; 2023 Dec; ():. PubMed ID: 38106118
[TBL] [Abstract][Full Text] [Related]
6. Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3.
Galal KA; Krämer A; Strickland BG; Smith JL; Dickmander RJ; Moorman NJ; Willson TM
Bioorg Med Chem Lett; 2024 Feb; 99():129617. PubMed ID: 38199328
[TBL] [Abstract][Full Text] [Related]
7. Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Asquith CRM; Bennett JM; Su L; Laitinen T; Elkins JM; Pickett JE; Wells CI; Li Z; Willson TM; Zuercher WJ
Molecules; 2019 Nov; 24(22):. PubMed ID: 31698822
[TBL] [Abstract][Full Text] [Related]
8. Development of a potent and selective chemical probe for the pleiotropic kinase CK2.
Wells CI; Drewry DH; Pickett JE; Tjaden A; Krämer A; Müller S; Gyenis L; Menyhart D; Litchfield DW; Knapp S; Axtman AD
Cell Chem Biol; 2021 Apr; 28(4):546-558.e10. PubMed ID: 33484635
[TBL] [Abstract][Full Text] [Related]
9. Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases.
Ploemen JH; van Ommen B; Bogaards JJ; van Bladeren PJ
Xenobiotica; 1993 Aug; 23(8):913-23. PubMed ID: 8284946
[TBL] [Abstract][Full Text] [Related]
10. Discovery and Optimization of a Novel 2
Wei Y; Tang Y; Zhou Y; Yang Y; Cui Y; Wang X; Wang Y; Liu Y; Liu N; Wang Q; Li C; Ruan H; Zhou H; Wei M; Yang G; Yang C
J Med Chem; 2021 Jul; 64(13):9078-9099. PubMed ID: 34129329
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate.
Ploemen JH; van Ommen B; van Bladeren PJ
Biochem Pharmacol; 1990 Oct; 40(7):1631-5. PubMed ID: 2222516
[TBL] [Abstract][Full Text] [Related]
12. Reaction Phenotyping of Low-Turnover Compounds in Long-Term Hepatocyte Cultures Through Persistent Selective Inhibition of Cytochromes P450.
Smith S; Lyman M; Ma B; Tweedie D; Menzel K
Drug Metab Dispos; 2021 Nov; 49(11):995-1002. PubMed ID: 34407991
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of glutathione S-transferase activity in human melanoma cells by alpha,beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal.
Iersel ML; Ploemen JP; Struik I; van Amersfoort C; Keyzer AE; Schefferlie JG; van Bladeren PJ
Chem Biol Interact; 1996 Oct; 102(2):117-32. PubMed ID: 8950226
[TBL] [Abstract][Full Text] [Related]
14. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
Traxler P; Bold G; Frei J; Lang M; Lydon N; Mett H; Buchdunger E; Meyer T; Mueller M; Furet P
J Med Chem; 1997 Oct; 40(22):3601-16. PubMed ID: 9357527
[TBL] [Abstract][Full Text] [Related]
15. Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms.
Leung L; Yang X; Strelevitz TJ; Montgomery J; Brown MF; Zientek MA; Banfield C; Gilbert AM; Thorarensen A; Dowty ME
Drug Metab Dispos; 2017 Jan; 45(1):1-7. PubMed ID: 27784718
[TBL] [Abstract][Full Text] [Related]
16. Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions.
Potęga A; Kosno M; Mazerska Z
J Pharm Anal; 2021 Dec; 11(6):791-798. PubMed ID: 35028185
[TBL] [Abstract][Full Text] [Related]
17. Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-
Naglah AM; Askar AA; Hassan AS; Khatab TK; Al-Omar MA; Bhat MA
Molecules; 2020 Mar; 25(6):. PubMed ID: 32245177
[TBL] [Abstract][Full Text] [Related]
18. Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry.
Yamazaki H; Kuribayashi S; Inoue T; Tateno C; Nishikura Y; Oofusa K; Harada D; Naito S; Horie T; Ohta S
Chem Res Toxicol; 2010 Jan; 23(1):152-8. PubMed ID: 19928966
[TBL] [Abstract][Full Text] [Related]
19. Isoenzyme selective irreversible inhibition of rat and human glutathione S-transferases by ethacrynic acid and two brominated derivatives.
Ploemen JH; Bogaards JJ; Veldink GA; van Ommen B; Jansen DH; van Bladeren PJ
Biochem Pharmacol; 1993 Feb; 45(3):633-9. PubMed ID: 8442764
[TBL] [Abstract][Full Text] [Related]
20. Interactions of glutathione S-transferase-pi with ethacrynic acid and its glutathione conjugate.
Awasthi S; Srivastava SK; Ahmad F; Ahmad H; Ansari GA
Biochim Biophys Acta; 1993 Jul; 1164(2):173-8. PubMed ID: 8329448
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
