219 related articles for article (PubMed ID: 37902787)
1. Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
Sinatra L; Vogelmann A; Friedrich F; Tararina MA; Neuwirt E; Colcerasa A; König P; Toy L; Yesiloglu TZ; Hilscher S; Gaitzsch L; Papenkordt N; Zhai S; Zhang L; Romier C; Einsle O; Sippl W; Schutkowski M; Gross O; Bendas G; Christianson DW; Hansen FK; Jung M; Schiedel M
J Med Chem; 2023 Nov; 66(21):14787-14814. PubMed ID: 37902787
[TBL] [Abstract][Full Text] [Related]
2. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6.
Skoge RH; Ziegler M
J Cell Sci; 2016 Aug; 129(15):2972-82. PubMed ID: 27311481
[TBL] [Abstract][Full Text] [Related]
3. Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin.
Nahhas F; Dryden SC; Abrams J; Tainsky MA
Mol Cell Biochem; 2007 Sep; 303(1-2):221-30. PubMed ID: 17516032
[TBL] [Abstract][Full Text] [Related]
4. Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS.
Taes I; Timmers M; Hersmus N; Bento-Abreu A; Van Den Bosch L; Van Damme P; Auwerx J; Robberecht W
Hum Mol Genet; 2013 May; 22(9):1783-90. PubMed ID: 23364049
[TBL] [Abstract][Full Text] [Related]
5. Cortactin deacetylation by HDAC6 and SIRT2 regulates neuronal migration and dendrite morphogenesis during cerebral cortex development.
Kim JY; Hwang HG; Lee JY; Kim M; Kim JY
Mol Brain; 2020 Jul; 13(1):105. PubMed ID: 32711564
[TBL] [Abstract][Full Text] [Related]
6. Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels.
Skoge RH; Dölle C; Ziegler M
DNA Repair (Amst); 2014 Nov; 23():33-8. PubMed ID: 24814981
[TBL] [Abstract][Full Text] [Related]
7. MeCP2 deficiency is associated with reduced levels of tubulin acetylation and can be restored using HDAC6 inhibitors.
Gold WA; Lacina TA; Cantrill LC; Christodoulou J
J Mol Med (Berl); 2015 Jan; 93(1):63-72. PubMed ID: 25209898
[TBL] [Abstract][Full Text] [Related]
8. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation.
Haggarty SJ; Koeller KM; Wong JC; Grozinger CM; Schreiber SL
Proc Natl Acad Sci U S A; 2003 Apr; 100(8):4389-94. PubMed ID: 12677000
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction.
Wattanathamsan O; Chantaravisoot N; Wongkongkathep P; Kungsukool S; Chetprayoon P; Chanvorachote P; Vinayanuwattikun C; Pongrakhananon V
J Biomed Sci; 2023 Jan; 30(1):4. PubMed ID: 36639650
[TBL] [Abstract][Full Text] [Related]
10. Structural insights into HDAC6 tubulin deacetylation and its selective inhibition.
Miyake Y; Keusch JJ; Wang L; Saito M; Hess D; Wang X; Melancon BJ; Helquist P; Gut H; Matthias P
Nat Chem Biol; 2016 Sep; 12(9):748-54. PubMed ID: 27454931
[TBL] [Abstract][Full Text] [Related]
11. Histone deacetylase inhibitors that target tubulin.
Schemies J; Sippl W; Jung M
Cancer Lett; 2009 Aug; 280(2):222-32. PubMed ID: 19268440
[TBL] [Abstract][Full Text] [Related]
12. Selective HDAC6 inhibition prevents TNF-α-induced lung endothelial cell barrier disruption and endotoxin-induced pulmonary edema.
Yu J; Ma Z; Shetty S; Ma M; Fu J
Am J Physiol Lung Cell Mol Physiol; 2016 Jul; 311(1):L39-47. PubMed ID: 27190059
[TBL] [Abstract][Full Text] [Related]
13. A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer.
Hoffmann G; Breitenbücher F; Schuler M; Ehrenhofer-Murray AE
J Biol Chem; 2014 Feb; 289(8):5208-16. PubMed ID: 24379401
[TBL] [Abstract][Full Text] [Related]
14. Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes.
Kozlov MV; Kleymenova AA; Konduktorov KA; Malikova AZ; Kochetkov SN
Biochemistry (Mosc); 2014 Jul; 79(7):637-42. PubMed ID: 25108326
[TBL] [Abstract][Full Text] [Related]
15. Acetylation/deacetylation and microtubule associated proteins influence flagellar axonemal stability and sperm motility.
Chawan V; Yevate S; Gajbhiye R; Kulkarni V; Parte P
Biosci Rep; 2020 Dec; 40(12):. PubMed ID: 33200789
[TBL] [Abstract][Full Text] [Related]
16. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
North BJ; Marshall BL; Borra MT; Denu JM; Verdin E
Mol Cell; 2003 Feb; 11(2):437-44. PubMed ID: 12620231
[TBL] [Abstract][Full Text] [Related]
17. Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors.
Yang L; Ma X; Yuan C; He Y; Li L; Fang S; Xia W; He T; Qian S; Xu Z; Li G; Wang Z
Eur J Med Chem; 2017 Jul; 134():230-241. PubMed ID: 28415012
[TBL] [Abstract][Full Text] [Related]
18. Fluorescence Polarization-Based Competition Assays to Evaluate Histone Deacetylase 6 Inhibitors.
Ashraf QF; Quilates EJ; Olaoye OO; de Araujo ED; Gunning PT
Methods Mol Biol; 2023; 2589():481-492. PubMed ID: 36255644
[TBL] [Abstract][Full Text] [Related]
19. HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes.
Noack M; Leyk J; Richter-Landsberg C
Glia; 2014 Apr; 62(4):535-47. PubMed ID: 24464872
[TBL] [Abstract][Full Text] [Related]
20. Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition.
Çetin Ö; Sari S; Erdem-Yurter H; Bora G
Drug Dev Res; 2022 Jun; 83(4):993-1002. PubMed ID: 35266183
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
