183 related articles for article (PubMed ID: 37906393)
1. Combining network pharmacology and experimental verification to reveal the mechanism of Chaigui granules in the treatment of depression through PI3K/Akt/mTOR signaling pathways.
Tian JS; Wu ZN; Wu D; Yang C; Gao Y; Yan DL; Qin XM
Metab Brain Dis; 2023 Dec; 38(8):2849-2864. PubMed ID: 37906393
[TBL] [Abstract][Full Text] [Related]
2. Isorhynchophylline exerts antidepressant-like effects in mice
Xian YF; Ip SP; Li HQ; Qu C; Su ZR; Chen JN; Lin ZX
FASEB J; 2019 Sep; 33(9):10393-10408. PubMed ID: 31233346
[TBL] [Abstract][Full Text] [Related]
3. The involvement of PI3K/Akt/mTOR/GSK3β signaling pathways in the antidepressant-like effect of AZD6765.
Neis VB; Moretti M; Rosa PB; Dalsenter YO; Werle I; Platt N; Kaufmann FN; Rosado AF; Besen MH; Rodrigues ALS
Pharmacol Biochem Behav; 2020 Nov; 198():173020. PubMed ID: 32861641
[TBL] [Abstract][Full Text] [Related]
4. Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice.
Ludka FK; Constantino LC; Dal-Cim T; Binder LB; Zomkowski A; Rodrigues AL; Tasca CI
J Psychiatr Res; 2016 Nov; 82():50-7. PubMed ID: 27468164
[TBL] [Abstract][Full Text] [Related]
5. PI3K/AKT/mTOR signaling-mediated neuropeptide VGF in the hippocampus of mice is involved in the rapid onset antidepressant-like effects of GLYX-13.
Lu Y; Wang C; Xue Z; Li C; Zhang J; Zhao X; Liu A; Wang Q; Zhou W
Int J Neuropsychopharmacol; 2014 Dec; 18(5):. PubMed ID: 25542689
[TBL] [Abstract][Full Text] [Related]
6. The effects and mechanisms of modified Xiaoyaosan on chronic unpredictable mild stress (CUMS)-induced depressive mice based on network pharmacology.
Liu Y; Guo D; Yu B; Zeng T; Jiao FL; Bi YM
J Ethnopharmacol; 2024 Apr; 324():117754. PubMed ID: 38232859
[TBL] [Abstract][Full Text] [Related]
7. Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Lin S; Chen Z; Wu Z; Fei F; Xu Z; Tong Y; Sun W; Wang P
Neurochem Res; 2024 Feb; 49(2):477-491. PubMed ID: 37935859
[TBL] [Abstract][Full Text] [Related]
8. The anti-depression effect and potential mechanism of the petroleum ether fraction of CDB: Integrated network pharmacology and metabolomics.
Zeng J; Chen L; Peng X; Luan F; Hu J; Xie Z; Xie H; Liu R; Lv H; Zeng N
Heliyon; 2024 Apr; 10(7):e28582. PubMed ID: 38586416
[TBL] [Abstract][Full Text] [Related]
9. IGF-1 defends against chronic-stress induced depression in rat models of chronic unpredictable mild stress through the PI3K/Akt/FoxO3a pathway.
Kuang WH; Dong ZQ; Tian LT; Li J
Kaohsiung J Med Sci; 2018 Jul; 34(7):370-376. PubMed ID: 30063009
[TBL] [Abstract][Full Text] [Related]
10. Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway.
Yao C; Zhang Y; Sun X; Pei H; Wei S; Wang M; Chang Q; Liu X; Jiang N
Biomed Pharmacother; 2023 Aug; 164():114459. PubMed ID: 37245336
[TBL] [Abstract][Full Text] [Related]
11. Xiaoyaosan ethyl acetate fraction alleviates depression-like behaviors in CUMS mice by promoting hippocampal neurogenesis via modulating the IGF-1Rβ/PI3K/Akt signaling pathway.
Zeng J; Ji Y; Luan F; Hu J; Rui Y; Liu Y; Rao Z; Liu R; Zeng N
J Ethnopharmacol; 2022 Apr; 288():115005. PubMed ID: 35051601
[TBL] [Abstract][Full Text] [Related]
12. Network Pharmacology and Experimental Evidence: PI3K/AKT Signaling Pathway is Involved in the Antidepressive Roles of Chaihu Shugan San.
Zhang S; Lu Y; Chen W; Shi W; Zhao Q; Zhao J; Li L
Drug Des Devel Ther; 2021; 15():3425-3441. PubMed ID: 34385814
[TBL] [Abstract][Full Text] [Related]
13. Metabolomics Based on Peripheral Blood Mononuclear Cells to Dissect the Mechanisms of Chaigui Granules for Treating Depression.
Huang D; Wang L; Wu Y; Qin X; Du G; Zhou Y
ACS Omega; 2022 Mar; 7(10):8466-8482. PubMed ID: 35309492
[TBL] [Abstract][Full Text] [Related]
14. Uncovering the active components, prospective targets, and molecular mechanism of Baihe Zhimu decoction for treating depression using network pharmacology-based analysis.
Wang HQ; Liu HT; Wang L; Min L; Chen B; Li H
J Ethnopharmacol; 2021 Dec; 281():114586. PubMed ID: 34464700
[TBL] [Abstract][Full Text] [Related]
15. Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation.
Xu M; Zhai W; Zhang Y; Pan J; Li J; Huang S
BMC Complement Med Ther; 2023 May; 23(1):156. PubMed ID: 37173696
[TBL] [Abstract][Full Text] [Related]
16. A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
Lin F; Zhang G; Yang X; Wang M; Wang R; Wan M; Wang J; Wu B; Yan T; Jia Y
J Ethnopharmacol; 2023 Mar; 303():115933. PubMed ID: 36403742
[TBL] [Abstract][Full Text] [Related]
17. Resveratrol exerts a protective effect in chronic unpredictable mild stress-induced depressive-like behavior: involvement of the AKT/GSK3β signaling pathway in hippocampus.
Shen J; Qu C; Xu L; Sun H; Zhang J
Psychopharmacology (Berl); 2019 Feb; 236(2):591-602. PubMed ID: 30374891
[TBL] [Abstract][Full Text] [Related]
18. Matrine Exerts Antidepressant-Like Effects on Mice: Role of the Hippocampal PI3K/Akt/mTOR Signaling.
Wu Z; You Z; Chen P; Chen C; Chen F; Shen J; Xu H
Int J Neuropsychopharmacol; 2018 Aug; 21(8):764-776. PubMed ID: 29668939
[TBL] [Abstract][Full Text] [Related]
19. Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
Wang J; Chen R; Liu C; Wu X; Zhang Y
Eur J Pharmacol; 2021 Oct; 909():174396. PubMed ID: 34332921
[TBL] [Abstract][Full Text] [Related]
20. Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice.
Su P; Wu M; Yin X; Li M; Li Y; Bai M; Wang B; Xu E
J Ethnopharmacol; 2023 Oct; 315():116659. PubMed ID: 37263314
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]