BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 37913894)

  • 1. An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies.
    Hasselluhn MC; Schlösser D; Versemann L; Schmidt GE; Ulisse M; Oschwald J; Zhang Z; Hamdan F; Xiao H; Kopp W; Spitalieri J; Kellner C; Schneider C; Reutlinger K; Nagarajan S; Steuber B; Sastra SA; Palermo CF; Appelhans J; Bohnenberger H; Todorovic J; Kostyuchek I; Ströbel P; Bockelmann A; König A; Ammer-Herrmenau C; Schmidleitner L; Kaulfuß S; Wollnik B; Hahn SA; Neesse A; Singh SK; Bastians H; Reichert M; Sax U; Olive KP; Johnsen SA; Schneider G; Ellenrieder V; Hessmann E
    Gastroenterology; 2024 Feb; 166(2):298-312.e14. PubMed ID: 37913894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal Adenocarcinoma.
    Hsieh YY; Liu TP; Chou CJ; Chen HY; Lee KH; Yang PM
    Genes (Basel); 2019 Sep; 10(10):. PubMed ID: 31569425
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and β-catenin signaling in pancreatic ductal adenocarcinoma cells.
    Li L; Li Z; Kong X; Xie D; Jia Z; Jiang W; Cui J; Du Y; Wei D; Huang S; Xie K
    Gastroenterology; 2014 Aug; 147(2):485-97.e18. PubMed ID: 24859161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression.
    Hasselluhn MC; Schmidt GE; Ellenrieder V; Johnsen SA; Hessmann E
    Cell Death Dis; 2019 Jun; 10(6):446. PubMed ID: 31171768
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SMAD4 loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells.
    Chen YW; Hsiao PJ; Weng CC; Kuo KK; Kuo TL; Wu DC; Hung WC; Cheng KH
    BMC Cancer; 2014 Mar; 14():181. PubMed ID: 24625091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.
    Eyres M; Lanfredini S; Xu H; Burns A; Blake A; Willenbrock F; Goldin R; Hughes D; Hughes S; Thapa A; Vavoulis D; Hubert A; D'Costa Z; Sabbagh A; Abraham AG; Blancher C; Jones S; Verrill C; Silva M; Soonawalla Z; Maughan T; Schuh A; Mukherjee S; O'Neill E
    Gastroenterology; 2021 Aug; 161(2):653-668.e16. PubMed ID: 33915173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Upregulated SMAD3 promotes epithelial-mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma.
    Yamazaki K; Masugi Y; Effendi K; Tsujikawa H; Hiraoka N; Kitago M; Shinoda M; Itano O; Tanabe M; Kitagawa Y; Sakamoto M
    Lab Invest; 2014 Jun; 94(6):683-91. PubMed ID: 24709776
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms.
    Yao H; Song W; Cao R; Ye C; Zhang L; Chen H; Wang J; Shi Y; Li R; Li Y; Liu X; Zhou X; Shao R; Li L
    Nat Commun; 2022 Sep; 13(1):5506. PubMed ID: 36127339
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis.
    Yasutome M; Gunn J; Korc M
    Clin Exp Metastasis; 2005; 22(6):461-73. PubMed ID: 16320109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4.
    Bertrand-Chapel A; Caligaris C; Fenouil T; Savary C; Aires S; Martel S; Huchedé P; Chassot C; Chauvet V; Cardot-Ruffino V; Morel AP; Subtil F; Mohkam K; Mabrut JY; Tonon L; Viari A; Cassier P; Hervieu V; Castets M; Mauviel A; Sentis S; Bartholin L
    Commun Biol; 2022 Oct; 5(1):1068. PubMed ID: 36207615
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphatase PPM1A is a novel prognostic marker in pancreatic ductal adenocarcinoma.
    Fan J; Yang MX; Ouyang Q; Fu D; Xu Z; Liu X; Mino-Kenudson M; Geng J; Tang F
    Hum Pathol; 2016 Sep; 55():151-8. PubMed ID: 27195906
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer.
    Liang C; Shi S; Qin Y; Meng Q; Hua J; Hu Q; Ji S; Zhang B; Xu J; Yu XJ
    Gut; 2020 May; 69(5):888-900. PubMed ID: 31611300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
    Nagathihalli NS; Castellanos JA; Shi C; Beesetty Y; Reyzer ML; Caprioli R; Chen X; Walsh AJ; Skala MC; Moses HL; Merchant NB
    Gastroenterology; 2015 Dec; 149(7):1932-1943.e9. PubMed ID: 26255562
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4.
    Xia X; Zhang K; Cen G; Jiang T; Cao J; Huang K; Huang C; Zhao Q; Qiu Z
    Oncotarget; 2015 Aug; 6(25):21046-63. PubMed ID: 26019136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status.
    Liang C; Xu J; Meng Q; Zhang B; Liu J; Hua J; Zhang Y; Shi S; Yu X
    Autophagy; 2020 Mar; 16(3):486-500. PubMed ID: 31177911
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
    Huang W; Navarro-Serer B; Jeong YJ; Chianchiano P; Xia L; Luchini C; Veronese N; Dowiak C; Ng T; Trujillo MA; Huang B; Pflüger MJ; Macgregor-Das AM; Lionheart G; Jones D; Fujikura K; Nguyen-Ngoc KV; Neumann NM; Groot VP; Hasanain A; van Oosten AF; Fischer SE; Gallinger S; Singhi AD; Zureikat AH; Brand RE; Gaida MM; Heinrich S; Burkhart RA; He J; Wolfgang CL; Goggins MG; Thompson ED; Roberts NJ; Ewald AJ; Wood LD
    Cancer Res; 2020 Jul; 80(13):2804-2817. PubMed ID: 32376602
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
    Chen NM; Singh G; Koenig A; Liou GY; Storz P; Zhang JS; Regul L; Nagarajan S; Kühnemuth B; Johnsen SA; Hebrok M; Siveke J; Billadeau DD; Ellenrieder V; Hessmann E
    Gastroenterology; 2015 May; 148(5):1024-1034.e9. PubMed ID: 25623042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.
    McDonald PC; Chafe SC; Brown WS; Saberi S; Swayampakula M; Venkateswaran G; Nemirovsky O; Gillespie JA; Karasinska JM; Kalloger SE; Supuran CT; Schaeffer DF; Bashashati A; Shah SP; Topham JT; Yapp DT; Li J; Renouf DJ; Stanger BZ; Dedhar S
    Gastroenterology; 2019 Sep; 157(3):823-837. PubMed ID: 31078621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SMAD4 endows TGF-β1-induced highly invasive tumor cells with ferroptosis vulnerability in pancreatic cancer.
    Chen HD; Ye Z; Hu HF; Fan GX; Hu YH; Li Z; Li BR; Ji SR; Zhou CJ; Xu XW; Yu XJ; Qin Y
    Acta Pharmacol Sin; 2024 Apr; 45(4):844-856. PubMed ID: 38057506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immunohistochemically detected expression of 3 major genes (CDKN2A/p16, TP53, and SMAD4/DPC4) strongly predicts survival in patients with resectable pancreatic cancer.
    Oshima M; Okano K; Muraki S; Haba R; Maeba T; Suzuki Y; Yachida S
    Ann Surg; 2013 Aug; 258(2):336-46. PubMed ID: 23470568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.