BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 37929724)

  • 1. Unveiling the ESR1 Conformational Stability and Screening Potent Inhibitors for Breast Cancer Treatment.
    Sharma K; Panwar U; Madhavi M; Joshi I; Chopra I; Soni L; Khan A; Bhrdwaj A; Parihar AS; Mohan VP; Prajapati L; Sharma R; Agrawal S; Hussain T; Nayarisseri A; Singh SK
    Med Chem; 2024; 20(3):352-368. PubMed ID: 37929724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel natural compound inhibitors targeting estrogen receptor α by an integrated virtual screening strategy.
    Yu E; Xu Y; Shi Y; Yu Q; Liu J; Xu L
    J Mol Model; 2019 Aug; 25(9):278. PubMed ID: 31463793
    [TBL] [Abstract][Full Text] [Related]  

  • 3.
    Bouricha EM; Hakmi M; Akachar J; Zouaidia F; Ibrahimi A
    J Biomol Struct Dyn; 2022 Jul; 40(11):5203-5210. PubMed ID: 33402049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In silico identification of novel inhibitors targeting the DNA-binding domain of the human estrogen receptor alpha.
    Cao H; Sun Y; Wang L; Pan Y; Li Z; Liang Y
    J Steroid Biochem Mol Biol; 2021 Oct; 213():105966. PubMed ID: 34416373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α.
    Singh K; Munuganti RS; Leblanc E; Lin YL; Leung E; Lallous N; Butler M; Cherkasov A; Rennie PS
    Breast Cancer Res; 2015 Feb; 17(1):27. PubMed ID: 25848700
    [TBL] [Abstract][Full Text] [Related]  

  • 6.
    Alamri A; Rauf A; Khalil AA; Alghamdi A; Alafnan A; Alshammari A; Alshammari F; Malik JA; Anwar S
    Biomed Res Int; 2021; 2021():9734279. PubMed ID: 34957309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Designer interface peptide grafts target estrogen receptor alpha dimerization.
    Chakraborty S; Asare BK; Biswas PK; Rajnarayanan RV
    Biochem Biophys Res Commun; 2016 Sep; 478(1):116-122. PubMed ID: 27462021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new class of 1,3,5-triazine-based selective estrogen receptor degraders (SERDs): Lead optimization, molecular docking and dynamic simulation.
    Lu X; Huang A; Xiao M; Sun L; Mao J; Luo G; Xiang H
    Bioorg Chem; 2020 Apr; 97():103666. PubMed ID: 32088420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Designing and optimization of novel human LMTK3 inhibitors against breast cancer - a computational approach.
    Anbarasu K; Jayanthi S
    J Recept Signal Transduct Res; 2017 Feb; 37(1):51-59. PubMed ID: 27056562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of leads targeting ER-α in breast cancer: An in silico exploration from natural domain.
    Ashtekar SS; Bhatia NM; Bhatia MS
    Steroids; 2018 Mar; 131():14-22. PubMed ID: 29307843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of 2,3-diaryl isoquinolinone derivatives as anti-breast cancer agents targeting ERα and VEGFR-2.
    Tang Z; Niu S; Liu F; Lao K; Miao J; Ji J; Wang X; Yan M; Zhang L; You Q; Xiao H; Xiang H
    Bioorg Med Chem Lett; 2014 May; 24(9):2129-33. PubMed ID: 24721727
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamics-Based Discovery of Novel, Potent Benzoic Acid Derivatives as Orally Bioavailable Selective Estrogen Receptor Degraders for ERα+ Breast Cancer.
    Zhang X; Wang Y; Li X; Wu J; Zhao L; Li W; Liu J
    J Med Chem; 2021 Jun; 64(11):7575-7595. PubMed ID: 34056898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in
    Hosfield DJ; Weber S; Li NS; Sauvage M; Joiner CF; Hancock GR; Sullivan EA; Ndukwe E; Han R; Cush S; Lainé M; Mader SC; Greene GL; Fanning SW
    Elife; 2022 May; 11():. PubMed ID: 35575456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational prediction for designing novel ketonic derivatives as potential inhibitors for breast cancer: A trade-off between drug likeness and inhibition potency.
    Muhammad S; Zahir N; Bibi S; Alshahrani MY; Shafiq-urRehman ; Chaudhry AR; Sarwar F; Tousif MI
    Comput Biol Chem; 2024 Apr; 109():108020. PubMed ID: 38286082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2H-chromen-2-one derivatives targeting ERα as anti-breast cancer agents.
    Luo G; Chen M; Lyu W; Zhao R; Xu Q; You Q; Xiang H
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2668-2673. PubMed ID: 28460819
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.
    Lappano R; Santolla MF; Pupo M; Sinicropi MS; Caruso A; Rosano C; Maggiolini M
    Breast Cancer Res; 2012 Jan; 14(1):R12. PubMed ID: 22251451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells.
    Li Z; Levine KM; Bahreini A; Wang P; Chu D; Park BH; Oesterreich S; Lee AV
    Endocrinology; 2018 Jan; 159(1):285-296. PubMed ID: 29029116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel hybrid conjugates with dual estrogen receptor α degradation and histone deacetylase inhibitory activities for breast cancer therapy.
    Zhao C; Tang C; Li C; Ning W; Hu Z; Xin L; Zhou HB; Huang J
    Bioorg Med Chem; 2021 Jun; 40():116185. PubMed ID: 33965842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer.
    Burks HE; Abrams T; Kirby CA; Baird J; Fekete A; Hamann LG; Kim S; Lombardo F; Loo A; Lubicka D; Macchi K; McDonnell DP; Mishina Y; Norris JD; Nunez J; Saran C; Sun Y; Thomsen NM; Wang C; Wang J; Peukert S
    J Med Chem; 2017 Apr; 60(7):2790-2818. PubMed ID: 28296398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In Silico docking studies of selected flavonoids--natural healing agents against breast cancer.
    Suganya J; Radha M; Naorem DL; Nishandhini M
    Asian Pac J Cancer Prev; 2014; 15(19):8155-9. PubMed ID: 25338999
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.