These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 37945897)

  • 21. Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification.
    Yang D; Ye F; Teijaro CN; Hwang D; Annaval T; Adhikari A; Li G; Yan X; Gui C; Rader C; Shen B
    Org Lett; 2022 Feb; 24(5):1219-1223. PubMed ID: 35084871
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pathway Retrofitting Yields Insights into the Biosynthesis of Anthraquinone-Fused Enediynes.
    Ma GL; Tran HT; Low ZJ; Candra H; Pang LM; Cheang QW; Fang M; Liang ZX
    J Am Chem Soc; 2021 Aug; 143(30):11500-11509. PubMed ID: 34293863
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.
    Annaval T; Rudolf JD; Chang CY; Lohman JR; Kim Y; Bigelow L; Jedrzejczak R; Babnigg G; Joachimiak A; Phillips GN; Shen B
    ACS Omega; 2017 Aug; 2(8):5159-5169. PubMed ID: 28884166
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes.
    Horsman GP; Chen Y; Thorson JS; Shen B
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11331-5. PubMed ID: 20534556
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Relative Reactivity of Benzothiophene-Fused Enediynes in the Bergman Cyclization.
    Lyapunova AG; Danilkina NA; Rumyantsev AM; Khlebnikov AF; Chislov MV; Starova GL; Sambuk EV; Govdi AI; Bräse S; Balova IA
    J Org Chem; 2018 Mar; 83(5):2788-2801. PubMed ID: 29402088
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Liposome-Encapsulated Tiancimycin A Is Active against Melanoma and Metastatic Breast Tumors: The Effect of cRGD Modification of the Liposomal Carrier and Tiancimycin A Dose on Drug Activity and Toxicity.
    Feng X; Liu H; Pan J; Xiong Y; Zhu X; Yan X; Duan Y; Huang Y
    Mol Pharm; 2022 Apr; 19(4):1078-1090. PubMed ID: 35290067
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.
    Yan X; Chen JJ; Adhikari A; Yang D; Crnovcic I; Wang N; Chang CY; Rader C; Shen B
    Org Lett; 2017 Nov; 19(22):6192-6195. PubMed ID: 29086572
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina.
    Kosgei AJ; Miller MD; Bhardwaj M; Xu W; Thorson JS; Van Lanen SG; Phillips GN
    Acta Crystallogr F Struct Biol Commun; 2022 Jan; 78(Pt 1):1-7. PubMed ID: 34981769
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics.
    Horsman GP; Lechner A; Ohnishi Y; Moore BS; Shen B
    Biochemistry; 2013 Aug; 52(31):5217-24. PubMed ID: 23844627
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures.
    Belecki K; Crawford JM; Townsend CA
    J Am Chem Soc; 2009 Sep; 131(35):12564-6. PubMed ID: 19689130
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate.
    Gui C; Kalkreuter E; Lauterbach L; Yang D; Shen B
    Nat Chem Biol; 2024 Jun; ():. PubMed ID: 38831037
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The synthesis and evaluation of 10- and 12-membered ring benzofused enediyne amino acids.
    Du Y; Creighton CJ; Yan Z; Gauthier DA; Dahl JP; Zhao B; Belkowski SM; Reitz AB
    Bioorg Med Chem; 2005 Nov; 13(21):5936-48. PubMed ID: 16140539
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and reactivity of cinnoline-fused cyclic enediyne.
    Vinogradova OV; Balova IA; Popik VV
    J Org Chem; 2011 Aug; 76(16):6937-41. PubMed ID: 21718062
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Towards photoswitchable enediyne antibiotics: single and two-photon triggering of bergman cyclization.
    Polukhtine A; Karpov G; Popik VV
    Curr Top Med Chem; 2008; 8(6):460-9. PubMed ID: 18397169
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships.
    Steele AD; Kiefer AF; Hwang D; Yang D; Teijaro CN; Adhikari A; Rader C; Shen B
    J Med Chem; 2023 Jan; 66(2):1562-1573. PubMed ID: 36599039
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.
    Li Y; Chooi YH; Sheng Y; Valentine JS; Tang Y
    J Am Chem Soc; 2011 Oct; 133(39):15773-85. PubMed ID: 21866960
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of the Biosynthetic Pathway of Beticolin 1 Reveals a Novel Non-Heme Iron-Dependent Oxygenase for Anthraquinone Ring Cleavage.
    Hou X; Xu H; Deng Z; Yan Y; Yuan Z; Liu X; Su Z; Yang S; Zhang Y; Rao Y
    Angew Chem Int Ed Engl; 2022 Sep; 61(37):e202208772. PubMed ID: 35862137
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027.
    Chang CY; Lohman JR; Huang T; Michalska K; Bigelow L; Rudolf JD; Jedrzejczak R; Yan X; Ma M; Babnigg G; Joachimiak A; Phillips GN; Shen B
    Biochemistry; 2018 Jun; 57(23):3278-3288. PubMed ID: 29533601
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of pentaene polyols by the activation of an enediyne gene cluster: biosynthetic implications for 9-membered enediyne core structures.
    Pan J; Tan Q; Zhu S; Yan X; Li Y; Zhuang Z; Zhu X; Duan Y; Huang Y
    Chem Sci; 2022 Nov; 13(45):13475-13481. PubMed ID: 36507168
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cofactor-independent C-C bond cleavage reactions catalyzed by the AlpJ family of oxygenases in atypical angucycline biosynthesis.
    Gao J; Li L; Shen S; Ai G; Wang B; Guo F; Yang T; Han H; Xu Z; Pan G; Fan K
    Beilstein J Org Chem; 2024; 20():1198-1206. PubMed ID: 38887580
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.