BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 37949065)

  • 1. Stress-induced β cell early senescence confers protection against type 1 diabetes.
    Lee H; Sahin GS; Chen CW; Sonthalia S; Cañas SM; Oktay HZ; Duckworth AT; Brawerman G; Thompson PJ; Hatzoglou M; Eizirik DL; Engin F
    Cell Metab; 2023 Dec; 35(12):2200-2215.e9. PubMed ID: 37949065
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.
    Lee H; Lee YS; Harenda Q; Pietrzak S; Oktay HZ; Schreiber S; Liao Y; Sonthalia S; Ciecko AE; Chen YG; Keles S; Sridharan R; Engin F
    Cell Metab; 2020 Apr; 31(4):822-836.e5. PubMed ID: 32220307
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.
    Morita S; Villalta SA; Feldman HC; Register AC; Rosenthal W; Hoffmann-Petersen IT; Mehdizadeh M; Ghosh R; Wang L; Colon-Negron K; Meza-Acevedo R; Backes BJ; Maly DJ; Bluestone JA; Papa FR
    Cell Metab; 2017 Apr; 25(4):883-897.e8. PubMed ID: 28380378
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes.
    Brozzi F; Eizirik DL
    Ups J Med Sci; 2016 May; 121(2):133-9. PubMed ID: 26899404
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Beta cell specific cannabinoid 1 receptor deletion counteracts progression to hyperglycemia in non-obese diabetic mice.
    Aseer KR; Mazucanti CH; O'Connell JF; González-Mariscal I; Verma A; Yao Q; Dunn C; Liu QR; Egan JM; Doyle ME
    Mol Metab; 2024 Apr; 82():101906. PubMed ID: 38423253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.
    Green-Mitchell SM; Tersey SA; Cole BK; Ma K; Kuhn NS; Cunningham TD; Maybee NA; Chakrabarti SK; McDuffie M; Taylor-Fishwick DA; Mirmira RG; Nadler JL; Morris MA
    PLoS One; 2013; 8(2):e56763. PubMed ID: 23437231
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes.
    Nigi L; Brusco N; Grieco GE; Licata G; Krogvold L; Marselli L; Gysemans C; Overbergh L; Marchetti P; Mathieu C; Dahl Jørgensen K; Sebastiani G; Dotta F
    Front Endocrinol (Lausanne); 2020; 11():630. PubMed ID: 33042009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA damage to β cells in culture recapitulates features of senescent β cells that accumulate in type 1 diabetes.
    Brawerman G; Pipella J; Thompson PJ
    Mol Metab; 2022 Aug; 62():101524. PubMed ID: 35660116
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes.
    Thompson PJ; Shah A; Apostolopolou H; Bhushan A
    Int J Mol Sci; 2019 Sep; 20(19):. PubMed ID: 31561444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis.
    Sahin GS; Lee H; Engin F
    Mol Metab; 2021 Dec; 54():101365. PubMed ID: 34728341
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes.
    Herlea-Pana O; Eeda V; Undi RB; Lim HY; Wang W
    Front Endocrinol (Lausanne); 2021; 12():749879. PubMed ID: 34675883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.
    Chan JY; Luzuriaga J; Maxwell EL; West PK; Bensellam M; Laybutt DR
    Mol Cell Endocrinol; 2015 Sep; 413():189-201. PubMed ID: 26135354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.
    Sala E; Vived C; Luna J; Saavedra-Ávila NA; Sengupta U; Castaño AR; Villar-Pazos S; Haba L; Verdaguer J; Ropero AB; Stratmann T; Pizarro J; Vázquez-Carrera M; Nadal A; Lahti JM; Mora C
    Front Immunol; 2021; 12():634797. PubMed ID: 33664748
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.
    Syed I; Rubin de Celis MF; Mohan JF; Moraes-Vieira PM; Vijayakumar A; Nelson AT; Siegel D; Saghatelian A; Mathis D; Kahn BB
    J Clin Invest; 2019 Aug; 129(9):3717-3731. PubMed ID: 31380811
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice.
    Kornete M; Beauchemin H; Polychronakos C; Piccirillo CA
    Autoimmunity; 2013 Jun; 46(4):259-68. PubMed ID: 23256897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
    Brozzi F; Gerlo S; Grieco FA; Nardelli TR; Lievens S; Gysemans C; Marselli L; Marchetti P; Mathieu C; Tavernier J; Eizirik DL
    J Biol Chem; 2014 Jul; 289(30):20677-93. PubMed ID: 24936061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Compound A attenuates proinflammatory cytokine-induced endoplasmic reticulum stress in beta cells and displays beneficial therapeutic effects in a mouse model of autoimmune diabetes.
    Andreone L; Fuertes F; Sétula C; Barcala Tabarrozzi AE; Orellano MS; Dewey RA; Bottino R; De Bosscher K; Perone MJ
    Cell Mol Life Sci; 2022 Nov; 79(12):587. PubMed ID: 36370223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.
    Brozzi F; Gerlo S; Grieco FA; Juusola M; Balhuizen A; Lievens S; Gysemans C; Bugliani M; Mathieu C; Marchetti P; Tavernier J; Eizirik DL
    J Biol Chem; 2016 Jun; 291(23):12040-56. PubMed ID: 27044747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells.
    Colli ML; Paula FM; Marselli L; Marchetti P; Roivainen M; Eizirik DL; Op de Beeck A
    J Innate Immun; 2019; 11(4):375-390. PubMed ID: 30799417
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes.
    Syed F; Singhal D; Raedschelders K; Krishnan P; Bone RN; McLaughlin MR; Van Eyk JE; Mirmira RG; Yang ML; Mamula MJ; Wu H; Liu X; Evans-Molina C
    EBioMedicine; 2023 Jan; 87():104379. PubMed ID: 36463755
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.