BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 37951450)

  • 1. Design, synthesis and anticancer evaluation of novel arylhydrazones of active methylene compounds.
    Murugesan A; Konda Mani S; Koochakkhani S; Subramanian K; Kandhavelu J; Thiyagarajan R; Gurbanov AV; Mahmudov KT; Kandhavelu M
    Int J Biol Macromol; 2024 Jan; 254(Pt 3):127909. PubMed ID: 37951450
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma.
    Viswanathan A; Kute D; Musa A; Konda Mani S; Sipilä V; Emmert-Streib F; Zubkov FI; Gurbanov AV; Yli-Harja O; Kandhavelu M
    Eur J Med Chem; 2019 Mar; 166():291-303. PubMed ID: 30731398
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Benzenesulfonamide Analogs: Synthesis, Anti-GBM Activity and Pharmacoprofiling.
    Murugesan A; Konda Mani S; Thiyagarajan R; Palanivel S; Gurbanov AV; Zubkov FI; Kandhavelu M
    Int J Mol Sci; 2023 Jul; 24(15):. PubMed ID: 37569654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hydrazide-hydrazones as Small Molecule Tropomyosin Receptor Kina se A (TRKA) Inhibitors: Synthesis, Anticancer Activities,
    Alam MS; Lee DU
    Med Chem; 2022; 19(1):47-63. PubMed ID: 35490310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, anticancer, and docking studies of salicyl-hydrazone analogues: A novel series of small potent tropomyosin receptor kinase A inhibitors.
    Alam MS; Choi SU; Lee DU
    Bioorg Med Chem; 2017 Jan; 25(1):389-396. PubMed ID: 27856237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.
    Olmez I; Zhang Y; Manigat L; Benamar M; Brenneman B; Nakano I; Godlewski J; Bronisz A; Lee J; Abbas T; Abounader R; Purow B
    Cancer Res; 2018 Aug; 78(15):4360-4369. PubMed ID: 29844123
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of aminopyridine derivatives as novel tropomyosin receptor kinase inhibitors.
    Lv R; Wang X; Sun Y; Qin Q; Liu N; Wu T; Sun Y; Yin W; Zhao D; Cheng M
    Arch Pharm (Weinheim); 2023 Mar; 356(3):e2200438. PubMed ID: 36398500
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulating Tumorigenicity and Cancer Metastasis through TRKA Signaling.
    Fan Y; Zhang B; Du X; Wang B; Yan Q; Guo L; Yao W
    Curr Cancer Drug Targets; 2024; 24(3):271-287. PubMed ID: 37670705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological activity of bicyclic carboxamide derivatives as TRK inhibitors.
    Sun M; Cai S; Li P; Zhang F; Zhang H; Zhou J
    Bioorg Med Chem; 2020 Dec; 28(23):115811. PubMed ID: 33069129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and Structure-Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors.
    Duan Y; Wang J; Zhu S; Tu ZC; Zhang Z; Chan S; Ding K
    Eur J Med Chem; 2020 Oct; 203():112552. PubMed ID: 32702585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TrkA overexpression in non-tumorigenic human breast cell lines confers oncogenic and metastatic properties.
    Kyker-Snowman K; Hughes RM; Yankaskas CL; Cravero K; Karthikeyan S; Button B; Waters I; Rosen DM; Dennison L; Hunter N; Donaldson J; Christenson ES; Konstantopoulos K; Hurley PJ; Croessmann S; Park BH
    Breast Cancer Res Treat; 2020 Feb; 179(3):631-642. PubMed ID: 31823098
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6
    Pan S; Zhang L; Luo X; Nan J; Yang W; Bin H; Li Y; Huang Q; Wang T; Pan Z; Mu B; Wang F; Tian C; Liu Y; Li L; Yang S
    J Med Chem; 2022 Feb; 65(3):2035-2058. PubMed ID: 35080890
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural characterization of nonactive site, TrkA-selective kinase inhibitors.
    Su HP; Rickert K; Burlein C; Narayan K; Bukhtiyarova M; Hurzy DM; Stump CA; Zhang X; Reid J; Krasowska-Zoladek A; Tummala S; Shipman JM; Kornienko M; Lemaire PA; Krosky D; Heller A; Achab A; Chamberlin C; Saradjian P; Sauvagnat B; Yang X; Ziebell MR; Nickbarg E; Sanders JM; Bilodeau MT; Carroll SS; Lumb KJ; Soisson SM; Henze DA; Cooke AJ
    Proc Natl Acad Sci U S A; 2017 Jan; 114(3):E297-E306. PubMed ID: 28039433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitogenesis in glioblastoma multiforme cell lines: a role for NGF and its TrkA receptors.
    Singer HS; Hansen B; Martinie D; Karp CL
    J Neurooncol; 1999; 45(1):1-8. PubMed ID: 10728904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
    Ardini E; Bosotti R; Borgia AL; De Ponti C; Somaschini A; Cammarota R; Amboldi N; Raddrizzani L; Milani A; Magnaghi P; Ballinari D; Casero D; Gasparri F; Banfi P; Avanzi N; Saccardo MB; Alzani R; Bandiera T; Felder E; Donati D; Pesenti E; Sartore-Bianchi A; Gambacorta M; Pierotti MA; Siena S; Veronese S; Galvani A; Isacchi A
    Mol Oncol; 2014 Dec; 8(8):1495-507. PubMed ID: 24962792
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of macrocyclic derivatives as TRK inhibitors.
    Li P; Cai S; Zhao T; Xu L; Guan D; Li J; Zhou J; Zhang H
    Bioorg Med Chem Lett; 2021 Dec; 53():128409. PubMed ID: 34628036
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel in-cell ELISA method for screening of compounds inhibiting TRKA phosphorylation, using KM12 cell line harboring TRKA rearrangement.
    Pandre MK; Shaik S; Satya Pratap VVV; Yadlapalli P; Yanamandra M; Mitra S
    Anal Biochem; 2018 Mar; 545():78-83. PubMed ID: 29360440
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyrizolo[1,5-a]pyrimidine derivatives of the second-generation TRK inhibitor: Design, synthesis and biological evaluation.
    Fan Y; Zhang Y; Liu Y; Jiang H; Zhou Y; Tang C; Fan W
    Bioorg Med Chem Lett; 2022 May; 63():128646. PubMed ID: 35231576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of WO2015042088 A1 - a novel urea-based scaffold for TrkA inhibition.
    Bernard-Gauthier V; Schirrmacher R
    Expert Opin Ther Pat; 2016; 26(2):291-5. PubMed ID: 26561352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autophagic cell death induced by TrkA receptor activation in human glioblastoma cells.
    Hansen K; Wagner B; Hamel W; Schweizer M; Haag F; Westphal M; Lamszus K
    J Neurochem; 2007 Oct; 103(1):259-75. PubMed ID: 17635673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.