BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 37954584)

  • 1. IRAK-4 inhibition: emavusertib for the treatment of lymphoid and myeloid malignancies.
    Parrondo RD; Iqbal M; Von Roemeling R; Von Roemeling C; Tun HW
    Front Immunol; 2023; 14():1239082. PubMed ID: 37954584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
    Choudhary GS; Pellagatti A; Agianian B; Smith MA; Bhagat TD; Gordon-Mitchell S; Sahu S; Pandey S; Shah N; Aluri S; Aggarwal R; Aminov S; Schwartz L; Steeples V; Booher RN; Ramachandra M; Samson M; Carbajal M; Pradhan K; Bowman TV; Pillai MM; Will B; Wickrema A; Shastri A; Bradley RK; Martell RE; Steidl UG; Gavathiotis E; Boultwood J; Starczynowski DT; Verma A
    Elife; 2022 Aug; 11():. PubMed ID: 36040792
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Bruton's tyrosine kinase in B cells and malignancies.
    Pal Singh S; Dammeijer F; Hendriks RW
    Mol Cancer; 2018 Feb; 17(1):57. PubMed ID: 29455639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia.
    Rushworth SA; Murray MY; Zaitseva L; Bowles KM; MacEwan DJ
    Blood; 2014 Feb; 123(8):1229-38. PubMed ID: 24307721
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML.
    Li S; Wu B; Zheng X; Wang C; Zhao J; Sun H; Sun X; Tang Z; Yuan H; Chen L; Ma X
    Bioorg Chem; 2021 Jan; 106():104385. PubMed ID: 33272709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting IRAK4 with Emavusertib in Lymphoma Models with Secondary Resistance to PI3K and BTK Inhibitors.
    Guidetti F; Arribas AJ; Sartori G; Spriano F; Barnabei L; Tarantelli C; Von Roemeling R; Martinez E; Zucca E; Bertoni F
    J Clin Med; 2023 Jan; 12(2):. PubMed ID: 36675328
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.
    Yang G; Zhou Y; Liu X; Xu L; Cao Y; Manning RJ; Patterson CJ; Buhrlage SJ; Gray N; Tai YT; Anderson KC; Hunter ZR; Treon SP
    Blood; 2013 Aug; 122(7):1222-32. PubMed ID: 23836557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors.
    Zhang Z; Zhang D; Liu Y; Yang D; Ran F; Wang ML; Zhao G
    Arch Pharm (Weinheim); 2018 Jul; 351(7):e1700369. PubMed ID: 29741794
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Bruton's tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages.
    Ping L; Ding N; Shi Y; Feng L; Li J; Liu Y; Lin Y; Shi C; Wang X; Pan Z; Song Y; Zhu J
    Oncotarget; 2017 Jun; 8(24):39218-39229. PubMed ID: 28424405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bruton's tyrosine kinase inhibitors in B-cell non-Hodgkin's lymphomas.
    Alinari L; Quinion C; Blum KA
    Clin Pharmacol Ther; 2015 May; 97(5):469-77. PubMed ID: 25670208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ibrutinib and indolent B-cell lymphomas.
    Akinleye A; Furqan M; Adekunle O
    Clin Lymphoma Myeloma Leuk; 2014 Aug; 14(4):253-60. PubMed ID: 24445187
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia.
    Pillinger G; Abdul-Aziz A; Zaitseva L; Lawes M; MacEwan DJ; Bowles KM; Rushworth SA
    Sci Rep; 2015 Aug; 5():12949. PubMed ID: 26292723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma.
    Ding N; Li X; Shi Y; Ping L; Wu L; Fu K; Feng L; Zheng X; Song Y; Pan Z; Zhu J
    Oncotarget; 2015 Jun; 6(17):15122-36. PubMed ID: 25944695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy.
    Kelly PN; Romero DL; Yang Y; Shaffer AL; Chaudhary D; Robinson S; Miao W; Rui L; Westlin WF; Kapeller R; Staudt LM
    J Exp Med; 2015 Dec; 212(13):2189-201. PubMed ID: 26621451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia.
    Wu H; Hu C; Wang A; Weisberg EL; Chen Y; Yun CH; Wang W; Liu Y; Liu X; Tian B; Wang J; Zhao Z; Liang Y; Li B; Wang L; Wang B; Chen C; Buhrlage SJ; Qi Z; Zou F; Nonami A; Li Y; Fernandes SM; Adamia S; Stone RM; Galinsky IA; Wang X; Yang G; Griffin JD; Brown JR; Eck MJ; Liu J; Gray NS; Liu Q
    Leukemia; 2016 Jan; 30(1):173-81. PubMed ID: 26165234
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.
    Oellerich T; Mohr S; Corso J; Beck J; Döbele C; Braun H; Cremer A; Münch S; Wicht J; Oellerich MF; Bug G; Bohnenberger H; Perske C; Schütz E; Urlaub H; Serve H
    Blood; 2015 Mar; 125(12):1936-47. PubMed ID: 25605370
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The future of B-cell lymphoma therapy: the B-cell receptor and its downstream pathways.
    Kenkre VP; Kahl BS
    Curr Hematol Malig Rep; 2012 Sep; 7(3):216-20. PubMed ID: 22688757
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Current Status of Bruton's Tyrosine Kinase Inhibitor Development and Use in B-Cell Malignancies.
    Aw A; Brown JR
    Drugs Aging; 2017 Jul; 34(7):509-527. PubMed ID: 28536906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
    Smith MA; Choudhary GS; Pellagatti A; Choi K; Bolanos LC; Bhagat TD; Gordon-Mitchell S; Von Ahrens D; Pradhan K; Steeples V; Kim S; Steidl U; Walter M; Fraser IDC; Kulkarni A; Salomonis N; Komurov K; Boultwood J; Verma A; Starczynowski DT
    Nat Cell Biol; 2019 May; 21(5):640-650. PubMed ID: 31011167
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting Bruton's tyrosine kinase in B cell malignancies.
    Hendriks RW; Yuvaraj S; Kil LP
    Nat Rev Cancer; 2014 Apr; 14(4):219-32. PubMed ID: 24658273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.