116 related articles for article (PubMed ID: 37955128)
1. Discovery of new VEGFR-2 inhibitors and apoptosis inducer-based thieno[2,3-
El-Metwally SA; Elkady H; Hagras M; Elkaeed EB; Alsfouk BA; Doghish AS; Ibrahim IM; Taghour MS; Husein DZ; Metwaly AM; Eissa IH
Future Med Chem; 2023 Nov; 15(22):2065-2086. PubMed ID: 37955128
[No Abstract] [Full Text] [Related]
2. New Thieno[2,3-d]pyrimidines as Anticancer VEGFR-2 Inhibitors with Apoptosis Induction: Design, Synthesis, and Biological and In Silico Studies.
Sobh EA; Dahab M; Elkaeed E; Alsfouk B; Ibrahim I; Metwaly AM; Eissa I
Med Chem; 2024 May; ():. PubMed ID: 38798211
[TBL] [Abstract][Full Text] [Related]
3. In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2.
El-Metwally SA; Abuelkhir AA; Elkady H; Taghour MS; Ibrahim IM; Husein DZ; Alsfouk AA; Sultan A; Ismail A; Elkhawaga SY; Elkaeed EB; Metwaly AM; Eissa IH
Comput Biol Chem; 2023 Oct; 106():107928. PubMed ID: 37480629
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, anti-proliferative evaluation, docking, and MD simulation studies of new thieno[2,3-
El-Metwally SA; Elkady H; Hagras M; Husein DZ; Ibrahim IM; Taghour MS; El-Mahdy HA; Ismail A; Alsfouk BA; Elkaeed EB; Metwaly AM; Eissa IH
RSC Adv; 2023 Jul; 13(33):23365-23385. PubMed ID: 37545598
[TBL] [Abstract][Full Text] [Related]
5. A novel thieno[2,3-d]pyrimidine derivative inhibiting vascular endothelial growth factor receptor-2: A story of computer-aided drug discovery.
Sobh EA; Dahab MA; Elkaeed EB; Alsfouk BA; Ibrahim IM; Metwaly AM; Eissa IH
Drug Dev Res; 2023 Sep; 84(6):1247-1265. PubMed ID: 37232504
[TBL] [Abstract][Full Text] [Related]
6. Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.
El-Metwally SA; Abou-El-Regal MM; Eissa IH; Mehany ABM; Mahdy HA; Elkady H; Elwan A; Elkaeed EB
Bioorg Chem; 2021 Jul; 112():104947. PubMed ID: 33964580
[TBL] [Abstract][Full Text] [Related]
7. Novel antiproliferative agents bearing substituted thieno[2,3-d]pyrimidine scaffold as dual VEGFR-2 and BRAF kinases inhibitors and apoptosis inducers; design, synthesis and molecular docking.
Hassan RA; Hamed MIA; Abdou AM; El-Dash Y
Bioorg Chem; 2022 Aug; 125():105861. PubMed ID: 35569190
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Potent VEGFR-2 Inhibitors based on Furopyrimidine and Thienopyrimidne Scaffolds as Cancer Targeting Agents.
Aziz MA; Serya RA; Lasheen DS; Abdel-Aziz AK; Esmat A; Mansour AM; Singab AN; Abouzid KA
Sci Rep; 2016 Apr; 6():24460. PubMed ID: 27080011
[TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of novel hexahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as potential anticancer agents with antiangiogenic activity via VEGFR-2 inhibition, and down-regulation of PI3K/AKT/mTOR signaling pathway.
Seif SE; Mahmoud Z; Wardakhan WW; Abdou AM; Hassan RA
Drug Dev Res; 2023 Aug; 84(5):839-860. PubMed ID: 37016480
[TBL] [Abstract][Full Text] [Related]
10. New C2- and N3-Modified Thieno[2,3-d]Pyrimidine Conjugates with Cytotoxicity in the Nanomolar Range.
Mavrova AT; Dimov S; Yancheva D; Rangelov M; Wesselinova D; Naydenova E
Anticancer Agents Med Chem; 2022; 22(6):1201-1212. PubMed ID: 34315388
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.
Yousef RG; Eldehna WM; Elwan A; Abdelaziz AS; Mehany ABM; Gobaara IMM; Alsfouk BA; Elkaeed EB; Metwaly AM; Eissa IH
Molecules; 2022 Jun; 27(13):. PubMed ID: 35807326
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
[TBL] [Abstract][Full Text] [Related]
13. Discovery of potent thieno[2,3-d]pyrimidine VEGFR-2 inhibitors: Design, synthesis and enzyme inhibitory evaluation supported by molecular dynamics simulations.
Elrazaz EZ; Serya RAT; Ismail NSM; Albohy A; Abou El Ella DA; Abouzid KAM
Bioorg Chem; 2021 Aug; 113():105019. PubMed ID: 34091286
[TBL] [Abstract][Full Text] [Related]
14. Discovery of new thieno[2,3-
Sobh EA; Dahab MA; Elkaeed EB; Alsfouk AA; Ibrahim IM; Metwaly AM; Eissa IH
Future Med Chem; 2023 Jul; 15(13):1167-1184. PubMed ID: 37529910
[No Abstract] [Full Text] [Related]
15. Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile.
Mghwary AE; Gedawy EM; Kamal AM; Abuel-Maaty SM
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):838-852. PubMed ID: 30919701
[TBL] [Abstract][Full Text] [Related]
16. Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.
Yousef RG; Ibrahim A; Khalifa MM; Eldehna WM; Gobaara IMM; Mehany ABM; Elkaeed EB; Alsfouk AA; Metwaly AM; Eissa IH
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1389-1403. PubMed ID: 35577416
[TBL] [Abstract][Full Text] [Related]
17. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
Li J; Gu W; Bi X; Li H; Liao C; Liu C; Huang W; Qian H
Bioorg Med Chem; 2017 Dec; 25(24):6674-6679. PubMed ID: 29146452
[TBL] [Abstract][Full Text] [Related]
19. Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors:
Eissa IH; Elkady H; Rashed M; Elwan A; Hagras M; Dahab MA; Taghour MS; Ibrahim IM; Husein DZ; Elkaeed EB; Al-Ghulikah HA; Metwaly AM; Mahdy HA
Heliyon; 2024 Jan; 10(2):e24005. PubMed ID: 38298627
[TBL] [Abstract][Full Text] [Related]
20. EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.
Mourad AAE; Farouk NA; El-Sayed EH; Mahdy ARE
Life Sci; 2021 Jul; 277():119531. PubMed ID: 33887348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
