215 related articles for article (PubMed ID: 37956301)
1. Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction.
Lundahl MN; Yang H; Broderick WE; Hoffman BM; Broderick JB
Proc Natl Acad Sci U S A; 2023 Nov; 120(47):e2314696120. PubMed ID: 37956301
[TBL] [Abstract][Full Text] [Related]
2. ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S]
Yang H; Ho MB; Lundahl MN; Mosquera MA; Broderick WE; Broderick JB; Hoffman BM
J Am Chem Soc; 2024 Feb; 146(6):3710-3720. PubMed ID: 38308759
[No Abstract] [Full Text] [Related]
3.
Lundahl MN; Sarksian R; Yang H; Jodts RJ; Pagnier A; Smith DF; Mosquera MA; van der Donk WA; Hoffman BM; Broderick WE; Broderick JB
J Am Chem Soc; 2022 Mar; 144(11):5087-5098. PubMed ID: 35258967
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of Radical Initiation in the Radical S-Adenosyl-l-methionine Superfamily.
Broderick WE; Hoffman BM; Broderick JB
Acc Chem Res; 2018 Nov; 51(11):2611-2619. PubMed ID: 30346729
[TBL] [Abstract][Full Text] [Related]
5. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
Byer AS; Yang H; McDaniel EC; Kathiresan V; Impano S; Pagnier A; Watts H; Denler C; Vagstad AL; Piel J; Duschene KS; Shepard EM; Shields TP; Scott LG; Lilla EA; Yokoyama K; Broderick WE; Hoffman BM; Broderick JB
J Am Chem Soc; 2018 Jul; 140(28):8634-8638. PubMed ID: 29954180
[TBL] [Abstract][Full Text] [Related]
6. Glycyl radical activating enzymes: structure, mechanism, and substrate interactions.
Shisler KA; Broderick JB
Arch Biochem Biophys; 2014 Mar; 546():64-71. PubMed ID: 24486374
[TBL] [Abstract][Full Text] [Related]
7. Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.
Moody JD; Hill S; Lundahl MN; Saxton AJ; Galambas A; Broderick WE; Lawrence CM; Broderick JB
J Biol Chem; 2023 Jun; 299(6):104791. PubMed ID: 37156396
[TBL] [Abstract][Full Text] [Related]
8. Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.
Pagnier A; Yang H; Jodts RJ; James CD; Shepard EM; Impano S; Broderick WE; Hoffman BM; Broderick JB
J Am Chem Soc; 2020 Oct; 142(43):18652-18660. PubMed ID: 32966073
[TBL] [Abstract][Full Text] [Related]
9. Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme.
Walsby CJ; Hong W; Broderick WE; Cheek J; Ortillo D; Broderick JB; Hoffman BM
J Am Chem Soc; 2002 Mar; 124(12):3143-51. PubMed ID: 11902903
[TBL] [Abstract][Full Text] [Related]
10. An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme.
Walsby CJ; Ortillo D; Broderick WE; Broderick JB; Hoffman BM
J Am Chem Soc; 2002 Sep; 124(38):11270-1. PubMed ID: 12236732
[TBL] [Abstract][Full Text] [Related]
11. Radical SAM enzymes: Nature's choice for radical reactions.
Broderick JB; Broderick WE; Hoffman BM
FEBS Lett; 2023 Jan; 597(1):92-101. PubMed ID: 36251330
[TBL] [Abstract][Full Text] [Related]
12. Photoinduced Electron Transfer in a Radical SAM Enzyme Generates an
Yang H; Impano S; Shepard EM; James CD; Broderick WE; Broderick JB; Hoffman BM
J Am Chem Soc; 2019 Oct; 141(40):16117-16124. PubMed ID: 31509404
[TBL] [Abstract][Full Text] [Related]
13. Pyruvate formate-lyase activating enzyme: elucidation of a novel mechanism for glycyl radical formation.
Buis JM; Broderick JB
Arch Biochem Biophys; 2005 Jan; 433(1):288-96. PubMed ID: 15581584
[TBL] [Abstract][Full Text] [Related]
14. Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
Horitani M; Shisler K; Broderick WE; Hutcheson RU; Duschene KS; Marts AR; Hoffman BM; Broderick JB
Science; 2016 May; 352(6287):822-5. PubMed ID: 27174986
[TBL] [Abstract][Full Text] [Related]
15. Coordination of adenosylmethionine to a unique iron site of the [4Fe-4S] of pyruvate formate-lyase activating enzyme: a Mössbauer spectroscopic study.
Krebs C; Broderick WE; Henshaw TF; Broderick JB; Huynh BH
J Am Chem Soc; 2002 Feb; 124(6):912-3. PubMed ID: 11829592
[TBL] [Abstract][Full Text] [Related]
16. Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme.
Cosper MM; Cosper NJ; Hong W; Shokes JE; Broderick WE; Broderick JB; Johnson MK; Scott RA
Protein Sci; 2003 Jul; 12(7):1573-7. PubMed ID: 12824504
[TBL] [Abstract][Full Text] [Related]
17. Mechanism of Radical Initiation in the Radical SAM Enzyme Superfamily.
Hoffman BM; Broderick WE; Broderick JB
Annu Rev Biochem; 2023 Jun; 92():333-349. PubMed ID: 37018846
[TBL] [Abstract][Full Text] [Related]
18. Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme.
Shisler KA; Hutcheson RU; Horitani M; Duschene KS; Crain AV; Byer AS; Shepard EM; Rasmussen A; Yang J; Broderick WE; Vey JL; Drennan CL; Hoffman BM; Broderick JB
J Am Chem Soc; 2017 Aug; 139(34):11803-11813. PubMed ID: 28768413
[TBL] [Abstract][Full Text] [Related]
19. The iron-sulfur cluster of pyruvate formate-lyase activating enzyme in whole cells: cluster interconversion and a valence-localized [4Fe-4S]2+ state.
Yang J; Naik SG; Ortillo DO; García-Serres R; Li M; Broderick WE; Huynh BH; Broderick JB
Biochemistry; 2009 Oct; 48(39):9234-41. PubMed ID: 19711960
[TBL] [Abstract][Full Text] [Related]
20. Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo
Sayler RI; Stich TA; Joshi S; Cooper N; Shaw JT; Begley TP; Tantillo DJ; Britt RD
ACS Cent Sci; 2019 Nov; 5(11):1777-1785. PubMed ID: 31807679
[No Abstract] [Full Text] [Related]
[Next] [New Search]
